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The map label for this gene is aroA [H]

Identifier: 161525429

GI number: 161525429

Start: 2472585

End: 2473889

Strand: Reverse

Name: aroA [H]

Synonym: Bmul_2259

Alternate gene names: 161525429

Gene position: 2473889-2472585 (Counterclockwise)

Preceding gene: 161525430

Following gene: 161525428

Centisome position: 71.74

GC content: 69.04

Gene sequence:

>1305_bases
ATGGACTATCTCGATCTCGGCCCGTATTCCAGTGCGTCGGGCACCGTGCGCCTGCCCGGCTCGAAGAGCATCTCGAACCG
CGTGCTGCTGCTCGCCGCGCTCGCCGAAGGCGACACGACGATCACGAACCTGCTCGATTCCGACGATACGCGCGTGATGC
TCGACGCGCTCGGCAAGCTCGGCGTGAAGCTCGCGCGCGATGGCGACACGTGTGTCGTCACCGGCACGCGCGGCGCGTTT
ACCGCGAAGACGGCCGATCTGTTCCTCGGCAATGCGGGCACGGCCGTGCGGCCGCTGACGGCGGCGCTCGCGATCAACGG
CGGCGACTATCGCGTGCACGGCGTGCCGCGCATGCACGAGCGGCCGATCGGCGATCTCGTCGACGGGCTGCGTCAGATCG
GCGCGCAGATCGACTACGAGCAGAACGAAGGCTTTCCGCCGCTGCGGATCCGGCCCGCGACGATCTCGGTCGACGCGCCG
ATCCGCGTGCGCGGCGACGTGTCGAGCCAGTTCCTCACCGCGCTGCTGATGACGCTGCCGCTCGTGAAGGCGAAGGACGG
CCGCAGCATCGTCGAGATCGACGGCGAACTGATCTCGAAGCCGTACATCGACATCACGATCCGGCTGATGGCGCGCTTCG
GCGTGAACGTCGAGCGCGAAGGCTGGCAGCGCTTCACGGTGCCGGCCGGCGTGCGCTACCGCTCGCCGGGGCGGATCATG
GTGGAGGGCGATGCGTCGTCGGCGTCGTACTTCCTCGCGGCCGGTGCGCTCGGCGGCGGCCCGCTGCGCGTCGAGGGCGT
CGGGCGCGCGAGCATCCAGGGCGACGTGGGCTTCGCCCACGCGCTGATGCAGATGGGCGCGAACGTGACGATGGGCGACG
ACTGGATCGAGGTGCGCGGCATCGGCCACGACCACGGCAAGCTCGAGCCGATCGACATGGACTTCAATCTGATTCCCGAC
GCGGCGATGACGATCGCGGTCGCGGCGCTGTTCGCGAACGGCACGAGCACGCTGCGCAACATCGCGAGCTGGCGCGTGAA
GGAAACCGACCGCATCGCCGCGATGGCGACCGAACTGCGCAAGGTCGGCGCGACCGTCGAGGAGGGCGCCGACTATCTCG
TCGTCACGCCGCCCGCGGCGCTCACGCCGAACGCCGCGATCGACACGTACGACGATCACCGGATGGCGATGTGCTTCTCG
CTCGTCAGCCTCGGCGGCGTGCCCGTGCGGATCAACGATCCGAAGTGCGTCGGCAAGACGTTCCCCGACTATTTCGACCG
CTTCGCCGCGCTCGCGAAGGCCTGA

Upstream 100 bases:

>100_bases
GAAGCGGTGTTCACGCGCTCGCGCGCGGCGCGCCGTGCATGGCAGGAGCGCGGCGCCAAGCCCGCTGCCGAAGCGGACAA
GCAATAACAGGACGATTCCC

Downstream 100 bases:

>100_bases
CCGACTGACCTGATGAAATCGACCCGACCCTTTCACCCGACCCCCGTCATCACGATCGACGGCCCGACCGCTTCCGGCAA
GGGCACCGTCGCGGCGCTGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAF
TAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYEQNEGFPPLRIRPATISVDAP
IRVRGDVSSQFLTALLMTLPLVKAKDGRSIVEIDGELISKPYIDITIRLMARFGVNVEREGWQRFTVPAGVRYRSPGRIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFAHALMQMGANVTMGDDWIEVRGIGHDHGKLEPIDMDFNLIPD
AAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAALTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA

Sequences:

>Translated_434_residues
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAF
TAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYEQNEGFPPLRIRPATISVDAP
IRVRGDVSSQFLTALLMTLPLVKAKDGRSIVEIDGELISKPYIDITIRLMARFGVNVEREGWQRFTVPAGVRYRSPGRIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFAHALMQMGANVTMGDDWIEVRGIGHDHGKLEPIDMDFNLIPD
AAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAALTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA
>Mature_434_residues
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKLGVKLARDGDTCVVTGTRGAF
TAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHERPIGDLVDGLRQIGAQIDYEQNEGFPPLRIRPATISVDAP
IRVRGDVSSQFLTALLMTLPLVKAKDGRSIVEIDGELISKPYIDITIRLMARFGVNVEREGWQRFTVPAGVRYRSPGRIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFAHALMQMGANVTMGDDWIEVRGIGHDHGKLEPIDMDFNLIPD
AAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELRKVGATVEEGADYLVVTPPAALTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFDRFAALAKA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=437, Percent_Identity=57.4370709382151, Blast_Score=460, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320332, Length=449, Percent_Identity=38.7527839643653, Blast_Score=249, Evalue=6e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46303; Mature: 46303

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEEHHHHHHHC
GVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHE
CEEEECCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAQIDYEQNEGFPPLRIRPATISVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCEEEECCCHHHHHHHHHHHHC
LVKAKDGRSIVEIDGELISKPYIDITIRLMARFGVNVEREGWQRFTVPAGVRYRSPGRIM
CEECCCCCEEEEECHHHHCCCCCEEEEEEHHHHCCCEECCCCEEEECCCCCEECCCCEEE
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFAHALMQMGANVTMGDDWIEVRG
EECCCCCCEEEEEECCCCCCCEEEEECCCEEECCCHHHHHHHHHCCCCEEECCCEEEEEE
IGHDHGKLEPIDMDFNLIPDAAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELR
CCCCCCCCEEECCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
KVGATVEEGADYLVVTPPAALTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKT
HHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCC
FPDYFDRFAALAKA
CHHHHHHHHHHHCC
>Mature Secondary Structure
MDYLDLGPYSSASGTVRLPGSKSISNRVLLLAALAEGDTTITNLLDSDDTRVMLDALGKL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEEHHHHHHHC
GVKLARDGDTCVVTGTRGAFTAKTADLFLGNAGTAVRPLTAALAINGGDYRVHGVPRMHE
CEEEECCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAQIDYEQNEGFPPLRIRPATISVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCEEEECCCHHHHHHHHHHHHC
LVKAKDGRSIVEIDGELISKPYIDITIRLMARFGVNVEREGWQRFTVPAGVRYRSPGRIM
CEECCCCCEEEEECHHHHCCCCCEEEEEEHHHHCCCEECCCCEEEECCCCCEECCCCEEE
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFAHALMQMGANVTMGDDWIEVRG
EECCCCCCEEEEEECCCCCCCEEEEECCCEEECCCHHHHHHHHHCCCCEEECCCEEEEEE
IGHDHGKLEPIDMDFNLIPDAAMTIAVAALFANGTSTLRNIASWRVKETDRIAAMATELR
CCCCCCCCEEECCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
KVGATVEEGADYLVVTPPAALTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKT
HHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCC
FPDYFDRFAALAKA
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA