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The map label for this gene is udg [H]

Identifier: 161525423

GI number: 161525423

Start: 2466463

End: 2467863

Strand: Reverse

Name: udg [H]

Synonym: Bmul_2253

Alternate gene names: 161525423

Gene position: 2467863-2466463 (Counterclockwise)

Preceding gene: 161525424

Following gene: 161525422

Centisome position: 71.56

GC content: 66.31

Gene sequence:

>1401_bases
ATGAAAATCACCATCATCGGCACGGGCTACGTCGGCCTCGTCACGGGCGCGTGTCTCGCGGAGATCGGCCACGACGTCTT
CTGTCTCGACGTCGATCCGCGCAAGATCGAGATCCTCAACAACGGCGGCGTGCCGATCCACGAACCGGGGCTGCTCGAGA
TCATCGCGCGCAACCGCTCGGCCGGACGCCTGCGTTTTTCGACCGATATCGAGGCCAGCGTCGCGCACGGCGAGATCCAG
TTCATCGCGGTCGGCACGCCGCCCGACGAAGACGGCTCGGCCGACCTGCAATACGTGCTCGAAGCCGCGCGCAACATCGG
CCGTCACATGACCGGCTTCAAGGTGATCGTCGACAAGTCGACGGTGCCCGTCGGCACCGCGCAGCGCGTGCGCGGCGTCG
TCGAGGAAGCGCTCGCCGCACGCGGCCTCGCGGGCAGCGTCGCGCATCGCTTCTCGGTCGTATCGAATCCCGAGTTCCTG
AAGGAAGGTGCGGCGGTCGACGACTTCATGCGTCCGGACCGCATCATCATCGGCGTCGACGACGACGAGACGGGCACGGT
CGCGCGCGAGAAGATGAAGAAGCTCTACGCGCCGTTCAACCGCAATCACGAGCGCACGATCTACATGGACGTGCGTTCCG
CCGAATTCTCGAAATACGCGGCGAACGCGATGCTTGCGACGCGCATCTCGTTCATGAACGAGATGTCGAATCTCGCCGAC
AAGGTCGGCGCCGACATCGAGGCCGTGCGCCGCGGCATCGGTTCGGATCCGCGCATCGGCTATCACTTCCTGTACGCGGG
TGTCGGCTATGGCGGTTCGTGCTTCCCGAAGGACGTGCAGGCGCTGATCCGCACCGCCGGTGAAAACGGCCAGCCGCTGC
GCATTCTCGAAGCGGTCGAAGCGGCCAACCATGCGCAGAAGGACGTGCTGATCGGCAAGATCGAGCGGCGTTTCGGCGCG
GATCTGAGCGGGCGCGAATTCGCCGTCTGGGGGCTCGCGTTCAAGCCCAACACCGACGACATGCGCGAGGCGCCGAGCCG
CCGTCTGATCGCGGCGCTGCTCGCGCGCGGCGCGACCGTGCGCGCCTACGATCCGGTCGCGCTCGACGAGGCGCGGCGCG
TGTTCGCGCTCGACCTCGGCGAAGGCTCGGACGCGCTCGCGCGGCTGCACTTCGTCGACACGCAGGACGCGGCGGTCATC
GGCGCGGACGCGCTCGTGATCGTCACCGAATGGAAGGAATTCAAGAGTCCGGATTTCACGCGCCTGAAGGCCGAACTGAA
GGCACCGGTGATTTTCGACGGGCGCAACCTGTACGAGCCCGACGCAATGGCCGAGCTCGGCATCGATTACTACGCGATCG
GGCGCCCCCATCTCGACCCGCAGGCCCACTCCCATGGATGA

Upstream 100 bases:

>100_bases
TGCCGGGCTGATCCCGGCCACGGCGCCGACGCATCGCGGTCGTCGCCGGGCGAAGCCCGGCGGCCAAGTTAGTCTATTAC
CGGGAAGCACCGGAACATCT

Downstream 100 bases:

>100_bases
ACGCACGATGACCACGCTTCGCGAAGTCGTTCCGGTTCCGCGCGACCAGATTGCTCGATCGCGCGTGCTCGTCGTCGGCG
ACGTGATGCTCGACCGCTAC

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIEILNNGGVPIHEPGLLEIIARNRSAGRLRFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTAQRVRGVVEEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVDDFMRPDRIIIGVDDDETGTVAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIERRFGA
DLSGREFAVWGLAFKPNTDDMREAPSRRLIAALLARGATVRAYDPVALDEARRVFALDLGEGSDALARLHFVDTQDAAVI
GADALVIVTEWKEFKSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPHLDPQAHSHG

Sequences:

>Translated_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIEILNNGGVPIHEPGLLEIIARNRSAGRLRFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTAQRVRGVVEEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVDDFMRPDRIIIGVDDDETGTVAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIERRFGA
DLSGREFAVWGLAFKPNTDDMREAPSRRLIAALLARGATVRAYDPVALDEARRVFALDLGEGSDALARLHFVDTQDAAVI
GADALVIVTEWKEFKSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPHLDPQAHSHG
>Mature_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIEILNNGGVPIHEPGLLEIIARNRSAGRLRFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTAQRVRGVVEEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVDDFMRPDRIIIGVDDDETGTVAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIERRFGA
DLSGREFAVWGLAFKPNTDDMREAPSRRLIAALLARGATVRAYDPVALDEARRVFALDLGEGSDALARLHFVDTQDAAVI
GADALVIVTEWKEFKSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPHLDPQAHSHG

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=35.031847133758, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI296040438, Length=373, Percent_Identity=35.1206434316354, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI296040443, Length=315, Percent_Identity=36.5079365079365, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1788340, Length=381, Percent_Identity=28.3464566929134, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI48994968, Length=427, Percent_Identity=27.8688524590164, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=477, Percent_Identity=35.2201257861635, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=35.3813559322034, Blast_Score=251, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50725; Mature: 50725

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIEILNNGGVPIHEPGLLEIIARNRS
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHEEEECCCC
AGRLRFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKS
CCEEEEECCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTAQRVRGVVEEALAARGLAGSVAHRFSVVSNPEFLKEGAAVDDFMRPDRIIIGVD
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHCCCCEEEEECC
DDETGTVAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AANHAQKDVLIGKIERRFGADLSGREFAVWGLAFKPNTDDMREAPSRRLIAALLARGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVALDEARRVFALDLGEGSDALARLHFVDTQDAAVIGADALVIVTEWKEFKSPDFT
EECCCCCHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEECCCEEEEEEECHHHCCCCHH
RLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPHLDPQAHSHG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIEILNNGGVPIHEPGLLEIIARNRS
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHEEEECCCC
AGRLRFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKS
CCEEEEECCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTAQRVRGVVEEALAARGLAGSVAHRFSVVSNPEFLKEGAAVDDFMRPDRIIIGVD
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHCCCCEEEEECC
DDETGTVAREKMKKLYAPFNRNHERTIYMDVRSAEFSKYAANAMLATRISFMNEMSNLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AANHAQKDVLIGKIERRFGADLSGREFAVWGLAFKPNTDDMREAPSRRLIAALLARGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVALDEARRVFALDLGEGSDALARLHFVDTQDAAVIGADALVIVTEWKEFKSPDFT
EECCCCCHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEECCCEEEEEEECHHHCCCCHH
RLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPHLDPQAHSHG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]