Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 161525330

GI number: 161525330

Start: 2375758

End: 2376345

Strand: Reverse

Name: pgsA [H]

Synonym: Bmul_2160

Alternate gene names: 161525330

Gene position: 2376345-2375758 (Counterclockwise)

Preceding gene: 161525331

Following gene: 161525327

Centisome position: 68.91

GC content: 63.44

Gene sequence:

>588_bases
ATGCCGTTCAATTTTCCGATTTTCCTGACGTGGGTGCGGATCGTGCTGATTCCGCTCGTCGTCGGCGTGTTCTATCTGCC
GGACACGGTGATGGGCGGCGCGCATCGCAATCTCGCGGCCGCGGCGATCTTCATCCTCGCGGCGCTGACGGACTGGTTCG
ACGGCTTTCTCGCGCGCAAATGGAACCAGACCTCGTCGTTCGGCGCGTTTCTCGATCCCGTCGCGGATAAGCTGATGGTG
ACGGCCGCGCTGCTGATCCTCGTGCAGATCTCGCGCGTCGATGCGGCGATCGCGCTCGTGATCGTCGGCCGCGAAATCGC
GATTTCGGCGTTGCGCGAATGGATGGCGCAGATCGGCGCGTCGAAGAGCGTCGCGGTGAACCAGCTCGGCAAGTTCAAGA
CTGCGTGCCAGATGGTCGCGATTCCGATGCTGCTGTACTACGGGCCGCTGCCGCTCGGCGTTGCGACGATCGACACGCGC
GTGTGGGGCGAGTGGCTGATGTATCTGGCGGCCATCCTGACGATCTGGTCGATGCTGTACTACATGAAGCTCGCGTGGCC
GCAGATTCGCGAGCGCAGCGGCGTGTGA

Upstream 100 bases:

>100_bases
CTGACGCGGCCGCCGCGGGCCGCGCGGCCCGCGCGCCGGCGTTCTTGTAGCGGGCCGGTCGACACGGCACAATTGCGAAT
CCTTTACTGTCCCGGATGCC

Downstream 100 bases:

>100_bases
CGCGCGTCGCGCGGGGCGGACGGCGAAAGTTTTTGGAAAAAGGGCGCGAAAAGCCCTTGACACACGAATGTGCCTTCGAC
ATAATCTCGCTTCTCCGCTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARKWNQTSSFGAFLDPVADKLMV
TAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGASKSVAVNQLGKFKTACQMVAIPMLLYYGPLPLGVATIDTR
VWGEWLMYLAAILTIWSMLYYMKLAWPQIRERSGV

Sequences:

>Translated_195_residues
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARKWNQTSSFGAFLDPVADKLMV
TAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGASKSVAVNQLGKFKTACQMVAIPMLLYYGPLPLGVATIDTR
VWGEWLMYLAAILTIWSMLYYMKLAWPQIRERSGV
>Mature_194_residues
PFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARKWNQTSSFGAFLDPVADKLMVT
AALLILVQISRVDAAIALVIVGREIAISALREWMAQIGASKSVAVNQLGKFKTACQMVAIPMLLYYGPLPLGVATIDTRV
WGEWLMYLAAILTIWSMLYYMKLAWPQIRERSGV

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=187, Percent_Identity=49.1978609625668, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21652; Mature: 21521

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSSFGAFLDPVADKLMVTAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNQLGKFKTACQMVAIPMLLYYGPLPLGVATIDTRVWGEWLMYLAAILTIWSMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMKLAWPQIRERSGV
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSSFGAFLDPVADKLMVTAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNQLGKFKTACQMVAIPMLLYYGPLPLGVATIDTRVWGEWLMYLAAILTIWSMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMKLAWPQIRERSGV
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]