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The map label for this gene is hpmB [H]

Identifier: 161525240

GI number: 161525240

Start: 2264729

End: 2266483

Strand: Reverse

Name: hpmB [H]

Synonym: Bmul_2070

Alternate gene names: 161525240

Gene position: 2266483-2264729 (Counterclockwise)

Preceding gene: 161525241

Following gene: 161525238

Centisome position: 65.72

GC content: 60.23

Gene sequence:

>1755_bases
GTGAGAGTTATTAGCGGGCGTGTCCAATTACAGGCGGTAGCTTCGTTCACGATTCATGCGCAGCAGGCCCCTACGTCTGC
CGATCACGCTGCGGCCGCTCGCGCAAACGCAGAACGGAACCAACAAGCGCAGCAGCAACGCGATGCGCAACAGCGTGCGG
CTGAAGTGCGTGCCCCTTCCGTTCGGTCGGACGTCCCGCGCATTGAAGCGTATCCGGCGCTTCCGATCGAAACGCCGTGT
TTCCGGATCGACCGGTTTGCGCTCGATGTGCCGAATTCATTGCCCGATGCAGCGAGGGTTCAGGGCGCGTCCGCCCTCCC
GATGGATCGATTTTCCTTCGCCCGCGAATGGTTGGAGCACTATGCCGGCCAGTGCGTCGGCAAGCAAGGTATCGATGTGC
TGGTCAAGGGTCTATCGCAAGCGATCCTGGCTCGCGGCTACGTGACGACACGTGTGCTGCTGCCCGAACAGGACCTGTCG
ACCGGTGCCCTCAAGTTTTCACTGATCCCCGGCGTGATCCGCCATGTGCGCTTCGCCGACGAAAAGCTCCGCGGCACCTG
GAAAACCGCCTTTCCGACTGGCGACGGCGAACTGCTGAATCTGCGCGACCTCGAACAGGGCCTCGAGCAGATGAAGCGCG
TGACGAGCCAGGACGTGTCGATGCAGATTGTGCCGGCCGACGTGCCCGGCGAAAGCGACGTCGTGCTCGACGTAAAGCGC
GGCAAGCCGTGGACCATCGTCGCGTCGATCGATAACTCCGGAACGCGTGCGACCGGGAAGCTGCAGGGCAATTTGTCGCT
CGGGATCGATAACCCGCTGGGCCTGAACGATGTCTTCAATATTGGCGTCAGCCAGGATCTCCAATTCGGCGACAAGCGCC
TGGGCTCGCATGGCTGGAATGGCTTCTATTCGATCCCGTGGGGCTACTGGACCGCGACGCTGTCCGCGTACACGAATACC
TACTACCAGCAAATCGCAGGCATGAACCAAACGTTCGTGGCGAGTGGCAATTCAAAGACGGTCGATTTCAAGCTGGCCCG
AGTGCTCGCCCGTAGCCAGAATGATGTGTTAGGTGCGTACGCTCGTCTGTCGCGTCGTTTCGGACAAAGCTTTATCGAAG
ACACCGAGATTTCGCAGCAACGTCGCAACAACACGATGATCGAGCTCGGGCTGACCGATCGCCACTACTTCGGTGGCGGC
CAGTTCGATGGCTCGCTTGCATATCGTCAAGGTGTCGGTGGATTGGGTGCTCAGGAAGATCGATTGGCAGCGGGTGGTGG
GCCGACCTATCGCTTCAAGATGGCCGTGCTGGATGCGAACCTGTCGGTGCCGTTCGCGATCGGCAAGCAGACGTTTCGCT
ATGTCGGCACGCTCCACGGCCAGTACACGGGCAACACACTCTATTACATCGATGACCTAACCATCGGTAGCCGCTACACC
GTACGTGGTTTCGACGGTGAAACGATGCTCGCCGCGGCGCGCGGATTCTATTGGCGCAACGAATTGCAGGCACCGATCGG
GCAGACGGGGCAGGCACTTTATGCGGGACTCGACTATGGTCGAGTCTGGGGCCCACAACCTGTTGCCCTAGTCGGTACGC
AGTTGGCTGGAGCAGTGATCGGCGTGAAGGGCAGCGTGGGCACGCGATTTGGAACCTATGCGTACGATCTCTTCGCCGGT
ACGCCGGTCTACAAGCCGTCAGGTTTTCCGACGGCACGTATGACGCTCGGTTTTCAGGTGACCGCTCAGTTCTAA

Upstream 100 bases:

>100_bases
CGCTGGTCTTTGTCGTGGCTCACGCCGGGCCTCTTCCTGTGAAAGATTCGCTTTTTTGGGTTTTCAGGTCAAGAACGTTT
GGGACCAGTGGAAACAATAA

Downstream 100 bases:

>100_bases
GACGATGACCCCAAGTACTGCACCGACACGGATACATCGCAAGCCCGATGTTGCATATGCTCGTCGGGCCGAGATTGCCG
CCAAACGGGGCTGACGCTTC

Product: polypeptide-transport-associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MRVISGRVQLQAVASFTIHAQQAPTSADHAAAARANAERNQQAQQQRDAQQRAAEVRAPSVRSDVPRIEAYPALPIETPC
FRIDRFALDVPNSLPDAARVQGASALPMDRFSFAREWLEHYAGQCVGKQGIDVLVKGLSQAILARGYVTTRVLLPEQDLS
TGALKFSLIPGVIRHVRFADEKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKR
GKPWTIVASIDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLQFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNT
YYQQIAGMNQTFVASGNSKTVDFKLARVLARSQNDVLGAYARLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGG
QFDGSLAYRQGVGGLGAQEDRLAAGGGPTYRFKMAVLDANLSVPFAIGKQTFRYVGTLHGQYTGNTLYYIDDLTIGSRYT
VRGFDGETMLAAARGFYWRNELQAPIGQTGQALYAGLDYGRVWGPQPVALVGTQLAGAVIGVKGSVGTRFGTYAYDLFAG
TPVYKPSGFPTARMTLGFQVTAQF

Sequences:

>Translated_584_residues
MRVISGRVQLQAVASFTIHAQQAPTSADHAAAARANAERNQQAQQQRDAQQRAAEVRAPSVRSDVPRIEAYPALPIETPC
FRIDRFALDVPNSLPDAARVQGASALPMDRFSFAREWLEHYAGQCVGKQGIDVLVKGLSQAILARGYVTTRVLLPEQDLS
TGALKFSLIPGVIRHVRFADEKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKR
GKPWTIVASIDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLQFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNT
YYQQIAGMNQTFVASGNSKTVDFKLARVLARSQNDVLGAYARLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGG
QFDGSLAYRQGVGGLGAQEDRLAAGGGPTYRFKMAVLDANLSVPFAIGKQTFRYVGTLHGQYTGNTLYYIDDLTIGSRYT
VRGFDGETMLAAARGFYWRNELQAPIGQTGQALYAGLDYGRVWGPQPVALVGTQLAGAVIGVKGSVGTRFGTYAYDLFAG
TPVYKPSGFPTARMTLGFQVTAQF
>Mature_584_residues
MRVISGRVQLQAVASFTIHAQQAPTSADHAAAARANAERNQQAQQQRDAQQRAAEVRAPSVRSDVPRIEAYPALPIETPC
FRIDRFALDVPNSLPDAARVQGASALPMDRFSFAREWLEHYAGQCVGKQGIDVLVKGLSQAILARGYVTTRVLLPEQDLS
TGALKFSLIPGVIRHVRFADEKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKR
GKPWTIVASIDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLQFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNT
YYQQIAGMNQTFVASGNSKTVDFKLARVLARSQNDVLGAYARLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGG
QFDGSLAYRQGVGGLGAQEDRLAAGGGPTYRFKMAVLDANLSVPFAIGKQTFRYVGTLHGQYTGNTLYYIDDLTIGSRYT
VRGFDGETMLAAARGFYWRNELQAPIGQTGQALYAGLDYGRVWGPQPVALVGTQLAGAVIGVKGSVGTRFGTYAYDLFAG
TPVYKPSGFPTARMTLGFQVTAQF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 63715; Mature: 63715

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVISGRVQLQAVASFTIHAQQAPTSADHAAAARANAERNQQAQQQRDAQQRAAEVRAPS
CCEECCCEEEEEEEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
VRSDVPRIEAYPALPIETPCFRIDRFALDVPNSLPDAARVQGASALPMDRFSFAREWLEH
HHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
YAGQCVGKQGIDVLVKGLSQAILARGYVTTRVLLPEQDLSTGALKFSLIPGVIRHVRFAD
HHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHH
EKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKR
HHHCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEC
GKPWTIVASIDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLQFGDKRLGSHGWN
CCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHCCCCCC
GFYSIPWGYWTATLSAYTNTYYQQIAGMNQTFVASGNSKTVDFKLARVLARSQNDVLGAY
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHHHCCCCHHHHHH
ARLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGGQFDGSLAYRQGVGGLGAQED
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCHHHHCCCCCCCCCCC
RLAAGGGPTYRFKMAVLDANLSVPFAIGKQTFRYVGTLHGQYTGNTLYYIDDLTIGSRYT
CEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCEECCCEEEEEEEEEECCEEE
VRGFDGETMLAAARGFYWRNELQAPIGQTGQALYAGLDYGRVWGPQPVALVGTQLAGAVI
EECCCCCCHHHHHHCCHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHEEHHHHHCEEE
GVKGSVGTRFGTYAYDLFAGTPVYKPSGFPTARMTLGFQVTAQF
EECCCCCCCCCCEEEEHHCCCCCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MRVISGRVQLQAVASFTIHAQQAPTSADHAAAARANAERNQQAQQQRDAQQRAAEVRAPS
CCEECCCEEEEEEEEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
VRSDVPRIEAYPALPIETPCFRIDRFALDVPNSLPDAARVQGASALPMDRFSFAREWLEH
HHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
YAGQCVGKQGIDVLVKGLSQAILARGYVTTRVLLPEQDLSTGALKFSLIPGVIRHVRFAD
HHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHH
EKLRGTWKTAFPTGDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKR
HHHCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEC
GKPWTIVASIDNSGTRATGKLQGNLSLGIDNPLGLNDVFNIGVSQDLQFGDKRLGSHGWN
CCCEEEEEEECCCCCEEEEEEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHCCCCCC
GFYSIPWGYWTATLSAYTNTYYQQIAGMNQTFVASGNSKTVDFKLARVLARSQNDVLGAY
CEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHHHCCCCHHHHHH
ARLSRRFGQSFIEDTEISQQRRNNTMIELGLTDRHYFGGGQFDGSLAYRQGVGGLGAQED
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCHHHHCCCCCCCCCCC
RLAAGGGPTYRFKMAVLDANLSVPFAIGKQTFRYVGTLHGQYTGNTLYYIDDLTIGSRYT
CEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCEECCCEEEEEEEEEECCEEE
VRGFDGETMLAAARGFYWRNELQAPIGQTGQALYAGLDYGRVWGPQPVALVGTQLAGAVI
EECCCCCCHHHHHHCCHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHEEHHHHHCEEE
GVKGSVGTRFGTYAYDLFAGTPVYKPSGFPTARMTLGFQVTAQF
EECCCCCCCCCCEEEEHHCCCCCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]