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The map label for this gene is appY [C]

Identifier: 161525238

GI number: 161525238

Start: 2262275

End: 2263294

Strand: Reverse

Name: appY [C]

Synonym: Bmul_2068

Alternate gene names: 161525238

Gene position: 2263294-2262275 (Counterclockwise)

Preceding gene: 161525240

Following gene: 161525237

Centisome position: 65.63

GC content: 68.04

Gene sequence:

>1020_bases
ATGACCGTCTGGAACTTCGCACGCAGCCCGGCTTCCGTCCTGCTCATGATCGAGTTCGGGCGCAGCCGGGCGATCGCGCC
GCCGGCGCTGCTCAAGGGCTCGCAGCTCACGCTGAAGCAGCTCGCCGACCCGGATTTCACCGTGCAGGCCGCGCAGGAGC
TGACCGTCGCGTCGAACCTGCTGAGGCTGACCGGAAACGAGGCCGGCGTGGGGCTGAAGGTCGGGCTGTCCTATCAGCTG
TCGGCCTACGGATTGCTCGGCTATGGGCTGATGAGCAGCGCGACGGGCCGCGACGCGATCGCGCTCGGCAGCCGCTATCT
GGCGCTGACCTATACCTTCGTCGGGATGCGTTATCGCCGCGTCGGGACGCACGACGCCGTCGTATTCGAACCGTCGCCGG
AGTTGTCGCCGCAGTTGCAACGCTTCTTCGTCGAGCGCGCGATGGGCGCAACCTGCCGCGTGCTGCGCGACGTGATGGGG
CCGGCCTTCGCGCTCGCGACCTTCGATCTCGCGTACGGCGCCGAGCCGGGCAGCCGTCAGCAGGTGCTGGGCACCAAGGT
CCGGTACGCGCAACCGGCGAACATGATCACGTTCGAGCATGCGCAACTCGAACGCCCGCTGCCGCAGGCGAACGCGGCGA
CCGCGGCGATGTGCGAGCGGATGTGCGCCGAGCTGCTGTCGCGCAGACGCACGCGCGTCGACATCGTGTCGTTCCTCAAC
GAATACCTGGCCACGCACGCGTTCGAGCGGCCGCCGCAACTGAAGGACATCGCGGCGCTGCTCAACACGAGCGAGCGCAC
GCTCAAGCGCCGGCTGCAGGAAGAGGGCGCGTGCTTTCGCGACATCTCGAATGCGGTCCGCAAGGCGCGCGCGCAGGCGC
TCGTTGCCGAAGGGCGGCTGTCGATCAAGGAGATTGCGCAGGAACTGGGGTTCAGCGACATGTCATCGTTCTCGCAGGCG
TACAAGCGCTGGACGGGCGTGGCGCCGAGCATGTCGCGGCAAAGGGCGGGCGGTTCGTAG

Upstream 100 bases:

>100_bases
GTTGCGATGGCCTCATCATGCTCGGCGGGCGTCGCGCGATCCATGCTGACGCAGGCCAACCGCTTTAGAATTCAGGCCAA
TGGACAACGCGAGGCGCTTC

Downstream 100 bases:

>100_bases
CGCGGGTTTGTAGCGGCGCTGGACGTCAGCAATGAGCGCAACGTAATCCAACGGAGCGATCGAACATGAAACTGCTGCTG
GTCGGCGCGACCGGTCTGGT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTVWNFARSPASVLLMIEFGRSRAIAPPALLKGSQLTLKQLADPDFTVQAAQELTVASNLLRLTGNEAGVGLKVGLSYQL
SAYGLLGYGLMSSATGRDAIALGSRYLALTYTFVGMRYRRVGTHDAVVFEPSPELSPQLQRFFVERAMGATCRVLRDVMG
PAFALATFDLAYGAEPGSRQQVLGTKVRYAQPANMITFEHAQLERPLPQANAATAAMCERMCAELLSRRRTRVDIVSFLN
EYLATHAFERPPQLKDIAALLNTSERTLKRRLQEEGACFRDISNAVRKARAQALVAEGRLSIKEIAQELGFSDMSSFSQA
YKRWTGVAPSMSRQRAGGS

Sequences:

>Translated_339_residues
MTVWNFARSPASVLLMIEFGRSRAIAPPALLKGSQLTLKQLADPDFTVQAAQELTVASNLLRLTGNEAGVGLKVGLSYQL
SAYGLLGYGLMSSATGRDAIALGSRYLALTYTFVGMRYRRVGTHDAVVFEPSPELSPQLQRFFVERAMGATCRVLRDVMG
PAFALATFDLAYGAEPGSRQQVLGTKVRYAQPANMITFEHAQLERPLPQANAATAAMCERMCAELLSRRRTRVDIVSFLN
EYLATHAFERPPQLKDIAALLNTSERTLKRRLQEEGACFRDISNAVRKARAQALVAEGRLSIKEIAQELGFSDMSSFSQA
YKRWTGVAPSMSRQRAGGS
>Mature_338_residues
TVWNFARSPASVLLMIEFGRSRAIAPPALLKGSQLTLKQLADPDFTVQAAQELTVASNLLRLTGNEAGVGLKVGLSYQLS
AYGLLGYGLMSSATGRDAIALGSRYLALTYTFVGMRYRRVGTHDAVVFEPSPELSPQLQRFFVERAMGATCRVLRDVMGP
AFALATFDLAYGAEPGSRQQVLGTKVRYAQPANMITFEHAQLERPLPQANAATAAMCERMCAELLSRRRTRVDIVSFLNE
YLATHAFERPPQLKDIAALLNTSERTLKRRLQEEGACFRDISNAVRKARAQALVAEGRLSIKEIAQELGFSDMSSFSQAY
KRWTGVAPSMSRQRAGGS

Specific function: Induces The Synthesis Of Acid Phosphatase (Appa) And Several Other Polypeptides (Such As Appbc) During The Deceleration Phase Of Growth. It Also Acts As A Transcriptional Repressor For One Group Of Proteins That Are Synthesized Preferentially In Exponenti

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786776, Length=139, Percent_Identity=32.3741007194245, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37193; Mature: 37062

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVWNFARSPASVLLMIEFGRSRAIAPPALLKGSQLTLKQLADPDFTVQAAQELTVASNL
CCCCCCCCCCCEEEEEEEECCCCCCCCHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
LRLTGNEAGVGLKVGLSYQLSAYGLLGYGLMSSATGRDAIALGSRYLALTYTFVGMRYRR
HHHCCCCCCCEEEECCEEEHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHC
VGTHDAVVFEPSPELSPQLQRFFVERAMGATCRVLRDVMGPAFALATFDLAYGAEPGSRQ
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCH
QVLGTKVRYAQPANMITFEHAQLERPLPQANAATAAMCERMCAELLSRRRTRVDIVSFLN
HHHHHHHHCCCCCCCEEECHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYLATHAFERPPQLKDIAALLNTSERTLKRRLQEEGACFRDISNAVRKARAQALVAEGRL
HHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
SIKEIAQELGFSDMSSFSQAYKRWTGVAPSMSRQRAGGS
CHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure 
TVWNFARSPASVLLMIEFGRSRAIAPPALLKGSQLTLKQLADPDFTVQAAQELTVASNL
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
LRLTGNEAGVGLKVGLSYQLSAYGLLGYGLMSSATGRDAIALGSRYLALTYTFVGMRYRR
HHHCCCCCCCEEEECCEEEHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHC
VGTHDAVVFEPSPELSPQLQRFFVERAMGATCRVLRDVMGPAFALATFDLAYGAEPGSRQ
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCH
QVLGTKVRYAQPANMITFEHAQLERPLPQANAATAAMCERMCAELLSRRRTRVDIVSFLN
HHHHHHHHCCCCCCCEEECHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYLATHAFERPPQLKDIAALLNTSERTLKRRLQEEGACFRDISNAVRKARAQALVAEGRL
HHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
SIKEIAQELGFSDMSSFSQAYKRWTGVAPSMSRQRAGGS
CHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12368430 [H]