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The map label for this gene is pccB [H]

Identifier: 161525218

GI number: 161525218

Start: 2241914

End: 2242846

Strand: Reverse

Name: pccB [H]

Synonym: Bmul_2048

Alternate gene names: 161525218

Gene position: 2242846-2241914 (Counterclockwise)

Preceding gene: 161525219

Following gene: 161525217

Centisome position: 65.04

GC content: 73.42

Gene sequence:

>933_bases
ATGACCGAAGCGATCCACGACGCGCCCGCGTTCGTCGCGAACGCGGCGAGCTGGTACGAGGCGTCGGCGCGGCAGCGCGT
CGACGCCTTGCTCGACGCCGGCAGCTTCACCGAATTCCTCGGGCCGGCCGAGCGCGTGACGAGCCCGCATCTGCCGCTGT
TCGACCTGCCGCAGCAGTTCGACGACGGGATGATCGTCGGCTGCGGCCGGCTCGACGGCAAGCCGGTGTTCGTCGCCGCG
CAGGAGGGCCGCTTCATGGGCGGCGCGTTCGGCGAAGTGCACGGTGCCAAGCTCACGGGCCTGCTGCGCGCCGCGCGCGA
CAGCGGCACGCCGGTGCTGATCCTGTTCGATACGGGCGGCGTGCGGCTGCAGGAAGCGAACGCGGGCGAGCTCGCGATCG
CCGAGATCATGCGTGCGCTCGTCGACGCGCGCGTGGCCGGCGTGCCGGTGATCGGGCTGATCGGCGGCCGCGCCGGCTGC
TACGGCGGCGGCGGGCTGCTCGCCGCGTGCTGCTCGGCGCTCGCGGTATCCGAGCAGGGCCGCATCAGCGTATCGGGACC
CGAAGTCATCGAGACCAACCGCGGCGTCGAGGAATTCGACGCGAAGGACCGCGCGCTGATCTGGCGCACGATGGGCGGCA
AGCACCGGCGGCTGATCGGCGGCGCGGAGCGCTACGTCGCCGACACGCCGGCCGCGTTTCGCGCGGCGGCGCTCGCGCTG
CTCGAGCGCGCGCCGAAACTCGATGTCGCGACGCTGCGTGCCGAGCAGGCGCGCCTCGACGCGCGCGTCGCGCGCTTCGG
CGCCTGCGAGGACGCGCTCGACGTCTGGCGTGCGCTCGGCGCGAGCGCGCCCGAGACGATCCCCGGCATGCCCGACGATG
CGTTCGCGACGCTCGCCGACCAACTGCAGGAGCCGCAGCATGACGCTCGATGA

Upstream 100 bases:

>100_bases
CGGGCGGCCTGAAGCTGTCGATCAACGACGGCGGCGCGCGGCCCGACATGGTGTCGCTGCGGCTCGCGCAGGCCGTGCGC
GCAATCGAAGGGGAGGCGTG

Downstream 100 bases:

>100_bases
GGTTCTGAATTCACTCTTTCCGCACGGCCATGCGATCGCGCGCGATCGCGGGCTGTTGACGGGCCACGCGTCGCTCGGCG
GCACGCGCGTCGACGTGATC

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTEAIHDAPAFVANAASWYEASARQRVDALLDAGSFTEFLGPAERVTSPHLPLFDLPQQFDDGMIVGCGRLDGKPVFVAA
QEGRFMGGAFGEVHGAKLTGLLRAARDSGTPVLILFDTGGVRLQEANAGELAIAEIMRALVDARVAGVPVIGLIGGRAGC
YGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGAERYVADTPAAFRAAALAL
LERAPKLDVATLRAEQARLDARVARFGACEDALDVWRALGASAPETIPGMPDDAFATLADQLQEPQHDAR

Sequences:

>Translated_310_residues
MTEAIHDAPAFVANAASWYEASARQRVDALLDAGSFTEFLGPAERVTSPHLPLFDLPQQFDDGMIVGCGRLDGKPVFVAA
QEGRFMGGAFGEVHGAKLTGLLRAARDSGTPVLILFDTGGVRLQEANAGELAIAEIMRALVDARVAGVPVIGLIGGRAGC
YGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGAERYVADTPAAFRAAALAL
LERAPKLDVATLRAEQARLDARVARFGACEDALDVWRALGASAPETIPGMPDDAFATLADQLQEPQHDAR
>Mature_309_residues
TEAIHDAPAFVANAASWYEASARQRVDALLDAGSFTEFLGPAERVTSPHLPLFDLPQQFDDGMIVGCGRLDGKPVFVAAQ
EGRFMGGAFGEVHGAKLTGLLRAARDSGTPVLILFDTGGVRLQEANAGELAIAEIMRALVDARVAGVPVIGLIGGRAGCY
GGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGAERYVADTPAAFRAAALALL
ERAPKLDVATLRAEQARLDARVARFGACEDALDVWRALGASAPETIPGMPDDAFATLADQLQEPQHDAR

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=181, Percent_Identity=30.939226519337, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788655, Length=185, Percent_Identity=31.3513513513514, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147359, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147362, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 32616; Mature: 32485

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAIHDAPAFVANAASWYEASARQRVDALLDAGSFTEFLGPAERVTSPHLPLFDLPQQF
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCCCCCCCHHC
DDGMIVGCGRLDGKPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARDSGTPVLILFDTGG
CCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
VRLQEANAGELAIAEIMRALVDARVAGVPVIGLIGGRAGCYGGGGLLAACCSALAVSEQG
EEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
RISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGAERYVADTPAAFRAAALAL
EEEECCCCEEECCCCHHHHCCCCCEEEEECCCCCCHHHHCCHHHHHCCCCHHHHHHHHHH
LERAPKLDVATLRAEQARLDARVARFGACEDALDVWRALGASAPETIPGMPDDAFATLAD
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QLQEPQHDAR
HHHCCCCCCC
>Mature Secondary Structure 
TEAIHDAPAFVANAASWYEASARQRVDALLDAGSFTEFLGPAERVTSPHLPLFDLPQQF
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCCCCCCCHHC
DDGMIVGCGRLDGKPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARDSGTPVLILFDTGG
CCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
VRLQEANAGELAIAEIMRALVDARVAGVPVIGLIGGRAGCYGGGGLLAACCSALAVSEQG
EEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
RISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGAERYVADTPAAFRAAALAL
EEEECCCCEEECCCCHHHHCCCCCEEEEECCCCCCHHHHCCHHHHHCCCCHHHHHHHHHH
LERAPKLDVATLRAEQARLDARVARFGACEDALDVWRALGASAPETIPGMPDDAFATLAD
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
QLQEPQHDAR
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]