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The map label for this gene is aaeR [H]

Identifier: 161525145

GI number: 161525145

Start: 2172864

End: 2173787

Strand: Reverse

Name: aaeR [H]

Synonym: Bmul_1973

Alternate gene names: 161525145

Gene position: 2173787-2172864 (Counterclockwise)

Preceding gene: 161525148

Following gene: 161525144

Centisome position: 63.04

GC content: 66.88

Gene sequence:

>924_bases
ATGGAACGATCGACCGCGCCGATGCAGGACCTCAACGACCTCTATTTCTTCGCTCAGGTGGTCGACCATCGCGGCTTCGC
ACCGGCCAGCCGCGCGCTCGGTATCCCGAAATCGACCTTGAGCCGGCGGATCGCCGCGCTCGAGCAGCAACTCGGCGTGC
GGCTCGTGCACCGGTCCACGCGGCAGTTCTCGATCACCGATATCGGTCAGCATTACTACAATCACTGCAAGGCAGTGCTG
GTCGAGGCCGAAGCGGCGCAGGACGCCATCGAGCAGATGCGCGCCGAGCCGCGCGGCGTGATCCGGCTCGTGTGCCCGGT
CGCGTTGCTGCACGCGCGGATCGCTCCGATGCTGGCCGAATTCATGGCCAAGACGCCGCGCGTCACGGTCCATCTCGAGG
CGACGAACCGCGTGGTCGACGTGATCGGCGAGGGCGTCGACGTTGCCCTGCGCGTGCGTCCGCCGCCGTTGAAGGATAGC
GACCTCGTGATGCGCGTGCTGGGCGAACGTGCATGGTCTCTCGTCGCGAGTCCGGCGCTCGTGCGGCAGCACGATATCGC
GGTGCCGGCCGATCTGGCCGGCTGCCCGACGCTCGATTTCGGGCCGCCGCAGCCGCAGCATGCGTGGCAACTCGAAGGCC
GCGATGGCGTGCAGACCACCATTCGGCATGTGCCGCGCTTCGTGACCGACGACATGGTTGCCTTGCGTCAAGCCGCGGTT
GCCGGCGTTGGCGTCGTACAACTGCCGATGATGATGGTGAGCGACGAGATCCGGCGCGGGGAGCTGGTTCGCGTCTTGCC
GGACTGGTTGCCGCGCAGCGGCATCATTCATGCGGTATTCCCGTCCCGCCGCGGGTTGCTGCCGTCGGTGCGCGCCTTGC
TGGACTTTCTGGTCGATGCGTTTGCGCGCATCGAGGAAACGTGA

Upstream 100 bases:

>100_bases
GCCGTAACGCCGCAGGGGGCGCTCGATGACGTGACGCGTAAGCGTAGGGGAGGATGTTTTGCGTCGGTAGACGGCGCGCG
TTATCCTCAGTGTCCCATTT

Downstream 100 bases:

>100_bases
TCCGAGTCGCGCAATGCCTGCGACCATGCGCCGATTGCCCTGCAGCAACAGGAGAACCCGATGATCAAGGTCAGTGTGAT
GTACCCGTACACCGCCGGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MERSTAPMQDLNDLYFFAQVVDHRGFAPASRALGIPKSTLSRRIAALEQQLGVRLVHRSTRQFSITDIGQHYYNHCKAVL
VEAEAAQDAIEQMRAEPRGVIRLVCPVALLHARIAPMLAEFMAKTPRVTVHLEATNRVVDVIGEGVDVALRVRPPPLKDS
DLVMRVLGERAWSLVASPALVRQHDIAVPADLAGCPTLDFGPPQPQHAWQLEGRDGVQTTIRHVPRFVTDDMVALRQAAV
AGVGVVQLPMMMVSDEIRRGELVRVLPDWLPRSGIIHAVFPSRRGLLPSVRALLDFLVDAFARIEET

Sequences:

>Translated_307_residues
MERSTAPMQDLNDLYFFAQVVDHRGFAPASRALGIPKSTLSRRIAALEQQLGVRLVHRSTRQFSITDIGQHYYNHCKAVL
VEAEAAQDAIEQMRAEPRGVIRLVCPVALLHARIAPMLAEFMAKTPRVTVHLEATNRVVDVIGEGVDVALRVRPPPLKDS
DLVMRVLGERAWSLVASPALVRQHDIAVPADLAGCPTLDFGPPQPQHAWQLEGRDGVQTTIRHVPRFVTDDMVALRQAAV
AGVGVVQLPMMMVSDEIRRGELVRVLPDWLPRSGIIHAVFPSRRGLLPSVRALLDFLVDAFARIEET
>Mature_307_residues
MERSTAPMQDLNDLYFFAQVVDHRGFAPASRALGIPKSTLSRRIAALEQQLGVRLVHRSTRQFSITDIGQHYYNHCKAVL
VEAEAAQDAIEQMRAEPRGVIRLVCPVALLHARIAPMLAEFMAKTPRVTVHLEATNRVVDVIGEGVDVALRVRPPPLKDS
DLVMRVLGERAWSLVASPALVRQHDIAVPADLAGCPTLDFGPPQPQHAWQLEGRDGVQTTIRHVPRFVTDDMVALRQAAV
AGVGVVQLPMMMVSDEIRRGELVRVLPDWLPRSGIIHAVFPSRRGLLPSVRALLDFLVDAFARIEET

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=29.8657718120805, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=30.7958477508651, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=30.0675675675676, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=27.3037542662116, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=25.8503401360544, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=25, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787589, Length=279, Percent_Identity=24.3727598566308, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082132, Length=269, Percent_Identity=27.1375464684015, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789173, Length=297, Percent_Identity=26.5993265993266, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI157672245, Length=183, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790011, Length=249, Percent_Identity=23.2931726907631, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=151, Percent_Identity=28.476821192053, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788706, Length=269, Percent_Identity=23.7918215613383, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33987; Mature: 33987

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSTAPMQDLNDLYFFAQVVDHRGFAPASRALGIPKSTLSRRIAALEQQLGVRLVHRST
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
RQFSITDIGQHYYNHCKAVLVEAEAAQDAIEQMRAEPRGVIRLVCPVALLHARIAPMLAE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FMAKTPRVTVHLEATNRVVDVIGEGVDVALRVRPPPLKDSDLVMRVLGERAWSLVASPAL
HHHCCCCEEEEEECHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHH
VRQHDIAVPADLAGCPTLDFGPPQPQHAWQLEGRDGVQTTIRHVPRFVTDDMVALRQAAV
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGVGVVQLPMMMVSDEIRRGELVRVLPDWLPRSGIIHAVFPSRRGLLPSVRALLDFLVDA
HCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
FARIEET
HHHHCCC
>Mature Secondary Structure
MERSTAPMQDLNDLYFFAQVVDHRGFAPASRALGIPKSTLSRRIAALEQQLGVRLVHRST
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
RQFSITDIGQHYYNHCKAVLVEAEAAQDAIEQMRAEPRGVIRLVCPVALLHARIAPMLAE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FMAKTPRVTVHLEATNRVVDVIGEGVDVALRVRPPPLKDSDLVMRVLGERAWSLVASPAL
HHHCCCCEEEEEECHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHH
VRQHDIAVPADLAGCPTLDFGPPQPQHAWQLEGRDGVQTTIRHVPRFVTDDMVALRQAAV
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGVGVVQLPMMMVSDEIRRGELVRVLPDWLPRSGIIHAVFPSRRGLLPSVRALLDFLVDA
HCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
FARIEET
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]