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The map label for this gene is iorA [H]

Identifier: 161525134

GI number: 161525134

Start: 2162146

End: 2162607

Strand: Reverse

Name: iorA [H]

Synonym: Bmul_1962

Alternate gene names: 161525134

Gene position: 2162607-2162146 (Counterclockwise)

Preceding gene: 161525135

Following gene: 161525133

Centisome position: 62.71

GC content: 66.88

Gene sequence:

>462_bases
ATGATCACGCTGACCCTCAACGGTAGCGAGCAGCACTTCGACGGCAATCCCGACATGCCGTTGCTCTGGTATCTGCGCGA
CGTGCTCGGTCACACGGGCACGAAGTTCGGCTGCGGCATGGCGCTCTGCGGCGCCTGTACTGTGCATCTCGACGGCGTCG
CGATCCGCTCGTGCATCACGCCGGTCGCGGCGGCCGCCGGCAAGCACGTGACGACGATCGAAGGACTGTCGGCCGACGCG
ACGCATCCGCTGCAGCAGGCCTGGCAGGAACTGAACGTCGCGCAATGCGGCTACTGTCAGGCCGGGCAGATCATGCAGGC
CGCGTCGCTGCTGAAGACGAACCCACACCCGACCGATGCCGACATCGACGACGCGATGTCCGGCAACATCTGCCGCTGCG
GCACCTACACGCGCATTCGCGCAGCGATCCGGCTCGCGGTGAGCCGCGGAGGTGCCGCATGA

Upstream 100 bases:

>100_bases
GCGCCGCGTGCGACACCTGCCGGCGGCGGCCGGCGACGCCCAATGCACGGTTCGGTTAAAGTCTGCGTGCAGGTAAGCGT
CCCCAACCAGGAGGTGAACA

Downstream 100 bases:

>100_bases
ACGGGCAGCCACTCTCCGTCTGCAACGAAAGCCGCCGCGCGCTGCTGCTCGGTTTCGCATCGGGCGGGCTGCTGCTCGCG
TTCGGCGTGCCGTCGCTCGC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MITLTLNGSEQHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCITPVAAAAGKHVTTIEGLSADA
THPLQQAWQELNVAQCGYCQAGQIMQAASLLKTNPHPTDADIDDAMSGNICRCGTYTRIRAAIRLAVSRGGAA

Sequences:

>Translated_153_residues
MITLTLNGSEQHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCITPVAAAAGKHVTTIEGLSADA
THPLQQAWQELNVAQCGYCQAGQIMQAASLLKTNPHPTDADIDDAMSGNICRCGTYTRIRAAIRLAVSRGGAA
>Mature_153_residues
MITLTLNGSEQHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCITPVAAAAGKHVTTIEGLSADA
THPLQQAWQELNVAQCGYCQAGQIMQAASLLKTNPHPTDADIDDAMSGNICRCGTYTRIRAAIRLAVSRGGAA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=143, Percent_Identity=37.0629370629371, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=39.7515527950311, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=38.7323943661972, Blast_Score=84, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=150, Percent_Identity=41.3333333333333, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=35.7142857142857, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=165, Percent_Identity=34.5454545454545, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17737937, Length=136, Percent_Identity=36.7647058823529, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647193, Length=157, Percent_Identity=35.031847133758, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647199, Length=135, Percent_Identity=35.5555555555556, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=32.2368421052632, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24647195, Length=159, Percent_Identity=31.4465408805031, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647197, Length=159, Percent_Identity=31.4465408805031, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16097; Mature: 16097

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTLNGSEQHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCIT
CEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECHHHHHHHHH
PVAAAAGKHVTTIEGLSADATHPLQQAWQELNVAQCGYCQAGQIMQAASLLKTNPHPTDA
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHCCCCCCCC
DIDDAMSGNICRCGTYTRIRAAIRLAVSRGGAA
CCCHHCCCCEEECCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITLTLNGSEQHFDGNPDMPLLWYLRDVLGHTGTKFGCGMALCGACTVHLDGVAIRSCIT
CEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECHHHHHHHHH
PVAAAAGKHVTTIEGLSADATHPLQQAWQELNVAQCGYCQAGQIMQAASLLKTNPHPTDA
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHCCCCCCCC
DIDDAMSGNICRCGTYTRIRAAIRLAVSRGGAA
CCCHHCCCCEEECCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]