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The map label for this gene is pamO [H]

Identifier: 161525123

GI number: 161525123

Start: 2139352

End: 2140728

Strand: Reverse

Name: pamO [H]

Synonym: Bmul_1951

Alternate gene names: 161525123

Gene position: 2140728-2139352 (Counterclockwise)

Preceding gene: 161525124

Following gene: 161525122

Centisome position: 62.08

GC content: 66.59

Gene sequence:

>1377_bases
ATGACGGAACGCGACCATGGCAAGCGGTACTGCGTGATCGGCGCCGGTGCGGCGGGGATTGCGGCCGCGAAGAATCTCGC
GGCGCTCGGGATCGGCGTCGACGTCATCGAGCGCGAGGACGACGTTGGCGGCAACTGGTATTACGCGCGCCCGAGCGGCG
CCGTGTATCGGTCGATCCACATGATCAGCTCGAAGCGGTTTTCGGAGTACCCGGACTTCCCGATGCCGGACGACTATCCG
ACCTACGCACGCGGCGATCAGGCGCTCGCGTATCTGCGCGCGTATGCGCGGCACTTCGGCGTGTACGACCGGATCGAGTT
CGGCCGTTCGGTGCTCGAGATCGCGCCGGTGCCCGGCAGCACGCAATGGCGTGTCGAACTCGATCGCGGCGAGGTGCGGC
GCTATCGCGGCGTGATCGTCTGCAACGGACATCTGTCGCATCCGCAGCTGCCCGACTATCCGGGCCGCTTCGACGGGCTG
CAACTGCACTCGTCGCAATACCGGACGCCGGACATTTTCACCGGCAAGCGCGTGCTCGTGATCGGCGCCGGCAATTCGGG
CTGCGACATCGCGGTCGAAGCGTCGCATCACGCGGCGGCGGTCTTTCACAGCACGCGGCGCGGCTATTTCTACTGGCCGA
AATTTCTGTTCGGGATGCCGGCCGACGAATGGGCCGAATGGCCGCTGCGGCTGCGCATGCCGCTCTGGGCGCGCCGCTTC
TTCGGCGAGCGGCTGCTGCGGCTCACGACGGCCGGGCAGCCGGAGGACTACGGGTTGCGCAAGCCGGACCACAAGCTGTT
CGAGTCGCACTTCATCATCAATTCGACGCTGTTCTACCACCTCGGCCATGGCGATCTCGTCGCGCGGCCCGACGTGCGCG
CACTGCAGGGCGAGCGCGTCGCGTTCGTCGACGGCAGCGAGGAGGCGGTCGACGTGATCGTCTACGCGACCGGCTACCGG
CCGAGCTTTCCGTTCATCGATCAGGCGCATCTGCAGTGGGACAAGGCGCAGCCGAAGCTGTATCTGAACATGTTCGATGC
GCAGCATCGCGACCTGTTCTTCATCGGGCTGTTCCAGACGTCGACCGGCAACTGGCCGTTGATGGACTATCAGGCGCAAC
TGCTCGCACGCTATCTGCGCGCACGCGACGTCGCACCGCGCCGTGCCGCACACATCGACGAACTGATCCGGCGCGACCGT
TCCGACTGGAACGGCGGGATCGCGTTTCACCGCACGCCGCGTCACGTGATCGAAGTCGAACACTTCGCGTACCGGCTGCA
GCTGAAGCGCCTGATTCGCGCACTGTCGGCCGCTGCGGCTGCCGCACCGGTGTCGCGCGCGCAGCCGCACGCGGTTCGTC
CGGGAGGCGCATCGTGA

Upstream 100 bases:

>100_bases
TCGCGGAACTGCGCGACACCGCGCTCGTCGGCGACGCGCCAGCGGGCGCGTCCGCGGCCGAACCGGTGGCCGCATTCGAC
ACGAACGGGGGAGATGGACG

Downstream 100 bases:

>100_bases
ACCTCGTGACGATCGACCGCGTGTCGAAGACCTATCGGCTCGACAGCGTGCGCGTGAGCGCCATCGCCGATGTCTCGCTG
ACGCTCGCCGCCGGCCGCTT

Product: flavin-containing monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTERDHGKRYCVIGAGAAGIAAAKNLAALGIGVDVIEREDDVGGNWYYARPSGAVYRSIHMISSKRFSEYPDFPMPDDYP
TYARGDQALAYLRAYARHFGVYDRIEFGRSVLEIAPVPGSTQWRVELDRGEVRRYRGVIVCNGHLSHPQLPDYPGRFDGL
QLHSSQYRTPDIFTGKRVLVIGAGNSGCDIAVEASHHAAAVFHSTRRGYFYWPKFLFGMPADEWAEWPLRLRMPLWARRF
FGERLLRLTTAGQPEDYGLRKPDHKLFESHFIINSTLFYHLGHGDLVARPDVRALQGERVAFVDGSEEAVDVIVYATGYR
PSFPFIDQAHLQWDKAQPKLYLNMFDAQHRDLFFIGLFQTSTGNWPLMDYQAQLLARYLRARDVAPRRAAHIDELIRRDR
SDWNGGIAFHRTPRHVIEVEHFAYRLQLKRLIRALSAAAAAAPVSRAQPHAVRPGGAS

Sequences:

>Translated_458_residues
MTERDHGKRYCVIGAGAAGIAAAKNLAALGIGVDVIEREDDVGGNWYYARPSGAVYRSIHMISSKRFSEYPDFPMPDDYP
TYARGDQALAYLRAYARHFGVYDRIEFGRSVLEIAPVPGSTQWRVELDRGEVRRYRGVIVCNGHLSHPQLPDYPGRFDGL
QLHSSQYRTPDIFTGKRVLVIGAGNSGCDIAVEASHHAAAVFHSTRRGYFYWPKFLFGMPADEWAEWPLRLRMPLWARRF
FGERLLRLTTAGQPEDYGLRKPDHKLFESHFIINSTLFYHLGHGDLVARPDVRALQGERVAFVDGSEEAVDVIVYATGYR
PSFPFIDQAHLQWDKAQPKLYLNMFDAQHRDLFFIGLFQTSTGNWPLMDYQAQLLARYLRARDVAPRRAAHIDELIRRDR
SDWNGGIAFHRTPRHVIEVEHFAYRLQLKRLIRALSAAAAAAPVSRAQPHAVRPGGAS
>Mature_457_residues
TERDHGKRYCVIGAGAAGIAAAKNLAALGIGVDVIEREDDVGGNWYYARPSGAVYRSIHMISSKRFSEYPDFPMPDDYPT
YARGDQALAYLRAYARHFGVYDRIEFGRSVLEIAPVPGSTQWRVELDRGEVRRYRGVIVCNGHLSHPQLPDYPGRFDGLQ
LHSSQYRTPDIFTGKRVLVIGAGNSGCDIAVEASHHAAAVFHSTRRGYFYWPKFLFGMPADEWAEWPLRLRMPLWARRFF
GERLLRLTTAGQPEDYGLRKPDHKLFESHFIINSTLFYHLGHGDLVARPDVRALQGERVAFVDGSEEAVDVIVYATGYRP
SFPFIDQAHLQWDKAQPKLYLNMFDAQHRDLFFIGLFQTSTGNWPLMDYQAQLLARYLRARDVAPRRAAHIDELIRRDRS
DWNGGIAFHRTPRHVIEVEHFAYRLQLKRLIRALSAAAAAAPVSRAQPHAVRPGGAS

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=423, Percent_Identity=34.7517730496454, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI4503757, Length=417, Percent_Identity=33.3333333333333, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI4503759, Length=425, Percent_Identity=31.2941176470588, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI221316674, Length=429, Percent_Identity=30.7692307692308, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI221316672, Length=412, Percent_Identity=31.5533980582524, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI50541965, Length=457, Percent_Identity=26.4770240700219, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI50541961, Length=457, Percent_Identity=26.4770240700219, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI221316678, Length=230, Percent_Identity=38.2608695652174, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25145785, Length=439, Percent_Identity=29.6127562642369, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17541300, Length=447, Percent_Identity=27.9642058165548, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI25150462, Length=454, Percent_Identity=28.8546255506608, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17561948, Length=450, Percent_Identity=27.5555555555556, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17555726, Length=452, Percent_Identity=28.5398230088496, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI193202226, Length=209, Percent_Identity=32.0574162679426, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17506045, Length=209, Percent_Identity=30.622009569378, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321970, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19921694, Length=212, Percent_Identity=34.4339622641509, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI19922866, Length=216, Percent_Identity=32.8703703703704, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 52009; Mature: 51877

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERDHGKRYCVIGAGAAGIAAAKNLAALGIGVDVIEREDDVGGNWYYARPSGAVYRSIH
CCCCCCCCEEEEEECCCHHHHHHHHHHEEECCEEEEECCCCCCCCEEEECCCCHHHHHHH
MISSKRFSEYPDFPMPDDYPTYARGDQALAYLRAYARHFGVYDRIEFGRSVLEIAPVPGS
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCC
TQWRVELDRGEVRRYRGVIVCNGHLSHPQLPDYPGRFDGLQLHSSQYRTPDIFTGKRVLV
CEEEEEECCCHHHHHCCEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCEECCCEEEE
IGAGNSGCDIAVEASHHAAAVFHSTRRGYFYWPKFLFGMPADEWAEWPLRLRMPLWARRF
EECCCCCCEEEEECCCCEEEEEHHCCCCEEECCHHHHCCCHHHHHCCCEEECCHHHHHHH
FGERLLRLTTAGQPEDYGLRKPDHKLFESHFIINSTLFYHLGHGDLVARPDVRALQGERV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHEEEEEEEEEEECCCCEEECCCHHHHCCCEE
AFVDGSEEAVDVIVYATGYRPSFPFIDQAHLQWDKAQPKLYLNMFDAQHRDLFFIGLFQT
EEECCCCCEEEEEEEEECCCCCCCCCCHHHCEECCCCCEEEEEEECCCCCCEEEEEEEEC
STGNWPLMDYQAQLLARYLRARDVAPRRAAHIDELIRRDRSDWNGGIAFHRTPRHVIEVE
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHH
HFAYRLQLKRLIRALSAAAAAAPVSRAQPHAVRPGGAS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TERDHGKRYCVIGAGAAGIAAAKNLAALGIGVDVIEREDDVGGNWYYARPSGAVYRSIH
CCCCCCCEEEEEECCCHHHHHHHHHHEEECCEEEEECCCCCCCCEEEECCCCHHHHHHH
MISSKRFSEYPDFPMPDDYPTYARGDQALAYLRAYARHFGVYDRIEFGRSVLEIAPVPGS
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCCC
TQWRVELDRGEVRRYRGVIVCNGHLSHPQLPDYPGRFDGLQLHSSQYRTPDIFTGKRVLV
CEEEEEECCCHHHHHCCEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCEECCCEEEE
IGAGNSGCDIAVEASHHAAAVFHSTRRGYFYWPKFLFGMPADEWAEWPLRLRMPLWARRF
EECCCCCCEEEEECCCCEEEEEHHCCCCEEECCHHHHCCCHHHHHCCCEEECCHHHHHHH
FGERLLRLTTAGQPEDYGLRKPDHKLFESHFIINSTLFYHLGHGDLVARPDVRALQGERV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHEEEEEEEEEEECCCCEEECCCHHHHCCCEE
AFVDGSEEAVDVIVYATGYRPSFPFIDQAHLQWDKAQPKLYLNMFDAQHRDLFFIGLFQT
EEECCCCCEEEEEEEEECCCCCCCCCCHHHCEECCCCCEEEEEEECCCCCCEEEEEEEEC
STGNWPLMDYQAQLLARYLRARDVAPRRAAHIDELIRRDRSDWNGGIAFHRTPRHVIEVE
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHH
HFAYRLQLKRLIRALSAAAAAAPVSRAQPHAVRPGGAS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA