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The map label for this gene is lipA [H]

Identifier: 161525117

GI number: 161525117

Start: 2133511

End: 2134608

Strand: Reverse

Name: lipA [H]

Synonym: Bmul_1945

Alternate gene names: 161525117

Gene position: 2134608-2133511 (Counterclockwise)

Preceding gene: 161525118

Following gene: 161525116

Centisome position: 61.9

GC content: 69.85

Gene sequence:

>1098_bases
ATGTCGATCATTTCATGTGCGGCGCACGCCCTGCGCCGCGGACTGTTGCACGCGCGGGCGGCCGCGCGGATTGCCGCGTT
CGTCGCGGCGGGCGTGCTCGCGCCGTACGCGAGCGTGCAGGCGGCCGAGGCGGCCGTCGACGACTACGCGGCGACGCGCT
ATCCGATCGTGCTCGTGCACGGTCTGACCGGCACCGACGACTACTTCGGCGTCGTGCCGTACTGGTATGCGATCCAGTCG
GATCTCGAGCGGCACGGGGCGACCGTCTACGTCGCCGACCTATCGGGCTTTCAGAGCGATCTCGGGCCGAACGGGCGCGG
CGAACAACTGCTCGCATACGTGAAGCGCGTACTCGCGGTGACGGGCGCGACGAAGGTGAACCTGATCGGGCACAGCCAGG
GCGGGCTCACCGCGCGCTACGTGGCGGCCGTAGCGCCGGACAGCGTCGCGTCGGTGACGACGATCGCGACGCCGCATCGC
GGCTCGCCGTTCGCCGACTTCGTGCTCGATGCGCTGAAGCTCGATCCGACCGGGCTGTCGACGCCCGTGTTCGGCGCCTT
GCTGAACGTGTTCGGCGTGCTGACGAGCGGCTCGCACAACACGAACCAGGACGCGATCGCGGCGCTGAACGCGCTGAGCA
CGCCCTACGCGACGCGCTTCAACGCGCTGTTGCCGAGTGCGGGCCTCGCGCCGGCCGGCAGTTGCCGAGGCGGCGCGCCG
GTCGAATCGGTCGGCGGCAACACGCAGCTGCTGTACTCGTGGAGCGGCACCGCGTATCAGCCGACGTCGCTGCTCGGCAT
CGTGACGGGTGCGGTCGATACGAGCGTGCTGCCGCTCGTCGATCCGGCGAACGTGCTCGATCCGTCGACGCTCGTGTTCC
TGACCGCCGGCACCGTGATCGCGATGCGCGGCGGCGGCCCGAACGACGGCTTCACGCCGGCGTGCAGCGCGCGGTTCGGC
ACCGTGATCTCGACCGGCTACCGCTGGGATCACTTCGACGAGATCAATCAGCTGTTCGGGATCCGCGGCGCGTATGCGGA
AGATCCGGTCGCCGCGCTGCGCGTGCATGCGAACCGGCTGAAGCTGCAGGGCGTCTAG

Upstream 100 bases:

>100_bases
GGCGCGCCGCTGTTCGTCGCGTGGCAGCGGCGCGTCGCCGCACACGCGCGGCCGCGCACGCCGACGCAACACGTTTGATC
AGCCCGTCACGGAGGATTCG

Downstream 100 bases:

>100_bases
CCATGCGCGTACGGGCAACGGTCGCGCGCTGTGCGTCGTACGCGGCGGTGGGCGCGGTGACGGTCGCGGCGGTCTGGCAT
GCGTTCGGCACGCGCGCGTC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSIISCAAHALRRGLLHARAAARIAAFVAAGVLAPYASVQAAEAAVDDYAATRYPIVLVHGLTGTDDYFGVVPYWYAIQS
DLERHGATVYVADLSGFQSDLGPNGRGEQLLAYVKRVLAVTGATKVNLIGHSQGGLTARYVAAVAPDSVASVTTIATPHR
GSPFADFVLDALKLDPTGLSTPVFGALLNVFGVLTSGSHNTNQDAIAALNALSTPYATRFNALLPSAGLAPAGSCRGGAP
VESVGGNTQLLYSWSGTAYQPTSLLGIVTGAVDTSVLPLVDPANVLDPSTLVFLTAGTVIAMRGGGPNDGFTPACSARFG
TVISTGYRWDHFDEINQLFGIRGAYAEDPVAALRVHANRLKLQGV

Sequences:

>Translated_365_residues
MSIISCAAHALRRGLLHARAAARIAAFVAAGVLAPYASVQAAEAAVDDYAATRYPIVLVHGLTGTDDYFGVVPYWYAIQS
DLERHGATVYVADLSGFQSDLGPNGRGEQLLAYVKRVLAVTGATKVNLIGHSQGGLTARYVAAVAPDSVASVTTIATPHR
GSPFADFVLDALKLDPTGLSTPVFGALLNVFGVLTSGSHNTNQDAIAALNALSTPYATRFNALLPSAGLAPAGSCRGGAP
VESVGGNTQLLYSWSGTAYQPTSLLGIVTGAVDTSVLPLVDPANVLDPSTLVFLTAGTVIAMRGGGPNDGFTPACSARFG
TVISTGYRWDHFDEINQLFGIRGAYAEDPVAALRVHANRLKLQGV
>Mature_364_residues
SIISCAAHALRRGLLHARAAARIAAFVAAGVLAPYASVQAAEAAVDDYAATRYPIVLVHGLTGTDDYFGVVPYWYAIQSD
LERHGATVYVADLSGFQSDLGPNGRGEQLLAYVKRVLAVTGATKVNLIGHSQGGLTARYVAAVAPDSVASVTTIATPHRG
SPFADFVLDALKLDPTGLSTPVFGALLNVFGVLTSGSHNTNQDAIAALNALSTPYATRFNALLPSAGLAPAGSCRGGAPV
ESVGGNTQLLYSWSGTAYQPTSLLGIVTGAVDTSVLPLVDPANVLDPSTLVFLTAGTVIAMRGGGPNDGFTPACSARFGT
VISTGYRWDHFDEINQLFGIRGAYAEDPVAALRVHANRLKLQGV

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=170, Percent_Identity=27.6470588235294, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 37781; Mature: 37650

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIISCAAHALRRGLLHARAAARIAAFVAAGVLAPYASVQAAEAAVDDYAATRYPIVLVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GLTGTDDYFGVVPYWYAIQSDLERHGATVYVADLSGFQSDLGPNGRGEQLLAYVKRVLAV
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHH
TGATKVNLIGHSQGGLTARYVAAVAPDSVASVTTIATPHRGSPFADFVLDALKLDPTGLS
CCCCEEEEEECCCCCCEEEEHEEECCCCHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCC
TPVFGALLNVFGVLTSGSHNTNQDAIAALNALSTPYATRFNALLPSAGLAPAGSCRGGAP
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCC
VESVGGNTQLLYSWSGTAYQPTSLLGIVTGAVDTSVLPLVDPANVLDPSTLVFLTAGTVI
HHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECEEE
AMRGGGPNDGFTPACSARFGTVISTGYRWDHFDEINQLFGIRGAYAEDPVAALRVHANRL
EEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHE
KLQGV
EECCC
>Mature Secondary Structure 
SIISCAAHALRRGLLHARAAARIAAFVAAGVLAPYASVQAAEAAVDDYAATRYPIVLVH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GLTGTDDYFGVVPYWYAIQSDLERHGATVYVADLSGFQSDLGPNGRGEQLLAYVKRVLAV
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHH
TGATKVNLIGHSQGGLTARYVAAVAPDSVASVTTIATPHRGSPFADFVLDALKLDPTGLS
CCCCEEEEEECCCCCCEEEEHEEECCCCHHHEEEEECCCCCCCHHHHHHHHHHCCCCCCC
TPVFGALLNVFGVLTSGSHNTNQDAIAALNALSTPYATRFNALLPSAGLAPAGSCRGGAP
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCC
VESVGGNTQLLYSWSGTAYQPTSLLGIVTGAVDTSVLPLVDPANVLDPSTLVFLTAGTVI
HHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECEEE
AMRGGGPNDGFTPACSARFGTVISTGYRWDHFDEINQLFGIRGAYAEDPVAALRVHANRL
EEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHE
KLQGV
EECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1987151; 9032073; 9032074 [H]