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The map label for this gene is mmlH [H]

Identifier: 161524867

GI number: 161524867

Start: 1867048

End: 1868277

Strand: Direct

Name: mmlH [H]

Synonym: Bmul_1694

Alternate gene names: 161524867

Gene position: 1867048-1868277 (Clockwise)

Preceding gene: 161524866

Following gene: 161524869

Centisome position: 54.14

GC content: 64.15

Gene sequence:

>1230_bases
ATGAGCTGGTACAGCAAGATGTCCGTCACCGAAAAGCGGACCTTCATTTCCGCGGCGGGCGGCTGGGCGATGGACGCGCT
CGACTTCATGGTGTTCACGTTCGTGATCACGACGCTGATCTCGATTTTCAAGATCGACAGCACGCAGGCCGGCCTGCTGG
CGACCGTCACGTTGCTGTTCTCGGCCATCGGCGGCTGGATTGCCGGCATCCTCGCCGACCGCTACGGGCGCGTACGCATC
CTGCAGGCGACGATCCTCTGGTTCTCGGGCTGCACGGTGGCGATCGGCTTTGCGCAGAATTTCGAACAGATCTTCGTCCT
GCGGGCTCTGCAAGGGCTCGGCTTCGGCGGCGAATGGGCGGTCGGCTCGGTGCTGATGGGCGAAATCGTGCGGACCGAAT
TCCGCGGGCGAGCGGTCGGCACCGTGCAGAGCGCCTGGTCGATCGGCTGGGGGATCGCGGCCATCGTCTACACCGTTCTG
TTTTCCTGGCTGCCCGAAGACTATGCATGGCGTGCGCTGTTCTGGGTCGGCGCGCTGCCGGCGCTGCTGGTGCTGTACAT
GCGCAAGGGCGTGCCGGAACCTGAAGTATTCCAGCGTACCCGCAAGCAAGAGCAAGCCGGCAACAAGCGCACGTCCATCT
GGACGATCTTCTCGCCGTCGTTGATCAAGACGACGGCGCTGACCTCGTTGCTGTGCACCGGCGTTCAGGGCGGCTACTAC
GCGGTGACCACGTGGCTGCCCACGTTCCTGAAAACCGAGCGTCACCTGTCGGTGGTCGGCACGGGCGGCTATCTGCTGGT
CGTCATTCTCGGATCGTTCATCGGCTATCTCACCGGCGCATGGCTGACCGACCGCGCCGGCCGCCGCGCGAACCTGCTGA
TCTTCGCGATGCTGTCCGGCATCAGCATCTACGCCTATACGCAGCTTCGACTCACCAACGACCAGATGCTGATCCTCGGA
TTCCCGCTCGGCTTCGCGGCCTCGGGCATCTTCAGCGGCATGGGTGCTTACCTGACCGAACTGTTTCCGTCGGCCGTGCG
CGCCAACGGACAAGGCTTCGCGTACAACTTCGGGCGCGGCCTCGGCGCGTTGTTCCCGAGCCTCGTCGGGTATCTCGCCC
ACGGTTACGGGCTCGGCATGGCGATCGGCATGTTCGCGGGCGGCGCCTATCTGGTCGTGCTGATCACCGCGTTGCTCCTG
CCGGAAACGAAGGGACGCGAAATCAGCTGA

Upstream 100 bases:

>100_bases
TTCTCGTCGACAACCCGGCCCGCCTGTACGGTTTCCCGCCCGGCAATCCATAAACGACGCAAGCACGCGCCGCTCAGCGG
CCATATGACAAGGAGACAAG

Downstream 100 bases:

>100_bases
GCACCGCGCCGCGCCGCGACGGGCCGGTGCGGCGACGCTCATGCGAGCGGCACGTCGAACGCCACGTGCTGCCGCACGAG
TGCCAGCATGGCCGGAATCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSWYSKMSVTEKRTFISAAGGWAMDALDFMVFTFVITTLISIFKIDSTQAGLLATVTLLFSAIGGWIAGILADRYGRVRI
LQATILWFSGCTVAIGFAQNFEQIFVLRALQGLGFGGEWAVGSVLMGEIVRTEFRGRAVGTVQSAWSIGWGIAAIVYTVL
FSWLPEDYAWRALFWVGALPALLVLYMRKGVPEPEVFQRTRKQEQAGNKRTSIWTIFSPSLIKTTALTSLLCTGVQGGYY
AVTTWLPTFLKTERHLSVVGTGGYLLVVILGSFIGYLTGAWLTDRAGRRANLLIFAMLSGISIYAYTQLRLTNDQMLILG
FPLGFAASGIFSGMGAYLTELFPSAVRANGQGFAYNFGRGLGALFPSLVGYLAHGYGLGMAIGMFAGGAYLVVLITALLL
PETKGREIS

Sequences:

>Translated_409_residues
MSWYSKMSVTEKRTFISAAGGWAMDALDFMVFTFVITTLISIFKIDSTQAGLLATVTLLFSAIGGWIAGILADRYGRVRI
LQATILWFSGCTVAIGFAQNFEQIFVLRALQGLGFGGEWAVGSVLMGEIVRTEFRGRAVGTVQSAWSIGWGIAAIVYTVL
FSWLPEDYAWRALFWVGALPALLVLYMRKGVPEPEVFQRTRKQEQAGNKRTSIWTIFSPSLIKTTALTSLLCTGVQGGYY
AVTTWLPTFLKTERHLSVVGTGGYLLVVILGSFIGYLTGAWLTDRAGRRANLLIFAMLSGISIYAYTQLRLTNDQMLILG
FPLGFAASGIFSGMGAYLTELFPSAVRANGQGFAYNFGRGLGALFPSLVGYLAHGYGLGMAIGMFAGGAYLVVLITALLL
PETKGREIS
>Mature_408_residues
SWYSKMSVTEKRTFISAAGGWAMDALDFMVFTFVITTLISIFKIDSTQAGLLATVTLLFSAIGGWIAGILADRYGRVRIL
QATILWFSGCTVAIGFAQNFEQIFVLRALQGLGFGGEWAVGSVLMGEIVRTEFRGRAVGTVQSAWSIGWGIAAIVYTVLF
SWLPEDYAWRALFWVGALPALLVLYMRKGVPEPEVFQRTRKQEQAGNKRTSIWTIFSPSLIKTTALTSLLCTGVQGGYYA
VTTWLPTFLKTERHLSVVGTGGYLLVVILGSFIGYLTGAWLTDRAGRRANLLIFAMLSGISIYAYTQLRLTNDQMLILGF
PLGFAASGIFSGMGAYLTELFPSAVRANGQGFAYNFGRGLGALFPSLVGYLAHGYGLGMAIGMFAGGAYLVVLITALLLP
ETKGREIS

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=431, Percent_Identity=23.6658932714617, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87082404, Length=382, Percent_Identity=26.4397905759162, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI87082231, Length=460, Percent_Identity=25.6521739130435, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790550, Length=429, Percent_Identity=25.4079254079254, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87081723, Length=361, Percent_Identity=30.1939058171745, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788942, Length=393, Percent_Identity=26.972010178117, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786229, Length=432, Percent_Identity=23.3796296296296, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082159, Length=395, Percent_Identity=26.8354430379747, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789941, Length=427, Percent_Identity=27.4004683840749, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788292, Length=433, Percent_Identity=24.9422632794457, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789152, Length=373, Percent_Identity=23.8605898123324, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=437, Percent_Identity=24.7139588100687, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44436; Mature: 44304

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWYSKMSVTEKRTFISAAGGWAMDALDFMVFTFVITTLISIFKIDSTQAGLLATVTLLF
CCCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SAIGGWIAGILADRYGRVRILQATILWFSGCTVAIGFAQNFEQIFVLRALQGLGFGGEWA
HHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHH
VGSVLMGEIVRTEFRGRAVGTVQSAWSIGWGIAAIVYTVLFSWLPEDYAWRALFWVGALP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALLVLYMRKGVPEPEVFQRTRKQEQAGNKRTSIWTIFSPSLIKTTALTSLLCTGVQGGYY
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEE
AVTTWLPTFLKTERHLSVVGTGGYLLVVILGSFIGYLTGAWLTDRAGRRANLLIFAMLSG
EHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHC
ISIYAYTQLRLTNDQMLILGFPLGFAASGIFSGMGAYLTELFPSAVRANGQGFAYNFGRG
CEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCH
LGALFPSLVGYLAHGYGLGMAIGMFAGGAYLVVLITALLLPETKGREIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SWYSKMSVTEKRTFISAAGGWAMDALDFMVFTFVITTLISIFKIDSTQAGLLATVTLLF
CCHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
SAIGGWIAGILADRYGRVRILQATILWFSGCTVAIGFAQNFEQIFVLRALQGLGFGGEWA
HHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHH
VGSVLMGEIVRTEFRGRAVGTVQSAWSIGWGIAAIVYTVLFSWLPEDYAWRALFWVGALP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALLVLYMRKGVPEPEVFQRTRKQEQAGNKRTSIWTIFSPSLIKTTALTSLLCTGVQGGYY
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEE
AVTTWLPTFLKTERHLSVVGTGGYLLVVILGSFIGYLTGAWLTDRAGRRANLLIFAMLSG
EHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHC
ISIYAYTQLRLTNDQMLILGFPLGFAASGIFSGMGAYLTELFPSAVRANGQGFAYNFGRG
CEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCH
LGALFPSLVGYLAHGYGLGMAIGMFAGGAYLVVLITALLLPETKGREIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]