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The map label for this gene is hoxN [H]

Identifier: 161523945

GI number: 161523945

Start: 837375

End: 838388

Strand: Reverse

Name: hoxN [H]

Synonym: Bmul_0765

Alternate gene names: 161523945

Gene position: 838388-837375 (Counterclockwise)

Preceding gene: 161523946

Following gene: 161523943

Centisome position: 24.31

GC content: 69.33

Gene sequence:

>1014_bases
ATGTTGTCCGCCACGCCTGCGCTGCGCCGCCTGCTGATCCTCTATGCGGGGCTGATCGCCGCCAATGCGGCCGTCTGGCT
ATGGGCGCTCGCGGTGCTGCGCGCGCATCCGCTGCTGCTCGGCACCGCGGCGATCGCCTACGGGCTCGGCCTGCGTCATG
CGGTCGATGCCGACCACATCGCGGCGATCGACGTCGCGACGCGCAAGCTGATGCACGACGGCCGGCGCCCGCTGACGGTC
GGCCTCGCGTTCTCGCTCGGCCACTCGACGGTCGTGATCGCCGCGACGCTCGGCATCGCGCTCACCGCGTTCGCGCTGCG
CACACACTTCGATGCGTTTCGCGACATCGGCGGGACGATCGGCACGGCCGTGTCGGCGACGTTCCTGCTGGCACTCGCCT
GCGTGAACCTGATGATCCTGCGCGACGTCTGGCGGCGCTACCGCCGCGCGCCGGCCCACGCACACGACGGCGCGCATCGG
CATCGGCGAGACGGCCTGCTGTCGCGCCTGCTGCGCCCGCTGTTCCGCTTCGTCTCGAAGAGCTGGCACATGTATCCGAT
CGGCGTGCTGTTCGGTCTCGGCTTCGATACCGCGACCGAAATCGGCCTGCTCGCGATCGCGGCCGCGCAGGCGAGCCAGG
GCCTGCCGATCTATACGGTGATGCTGTTTCCCGCGCTGTTTACGGCCGGCATGACGCTGATCGATTCGACCGACAACGTG
CTGATGATTCATGCGTACGGGTGGGCAATGGACGACCCGCAGCGCAAATTGCTCTACAACGCGAGCATCACGCTCGTGTC
GGCGATCGTCGCGCTCGCGATCGGCGGCATCGAAGCGGCCGGGCTGCTCGCCGACAAGCTCGCGCTGACGGGCCCCGTGC
GCGACGCGCTCGATGCGCTCGGCGAACGCTTCGGCACGCTCGGCTACGCGATCGTCGCGCTGTTTATCGTCTGCTGGATC
GCGTCGATCCTGTTCCACCGCTGGCAGCGCGCGGCAGGCGCGCCGGCGCGCTGA

Upstream 100 bases:

>100_bases
TCCGGTTCCGGACGAGCTTTTTTTTCGGCGCGCCATCCGCACGCCGCGCATTTTTTTCGCGTGCCACAATGGCCGGCGTA
TCGTCCGATGGAACCTGCCG

Downstream 100 bases:

>100_bases
GCACCGCGCGCGCCGCCGCTCACAGCATCTCGAGCGGCCGCTTGCTGCGCGGCGCGCGGAAATACGCATCGAGCTGCGCG
TGCTCGTCGTCGGTCAGCAC

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLSATPALRRLLILYAGLIAANAAVWLWALAVLRAHPLLLGTAAIAYGLGLRHAVDADHIAAIDVATRKLMHDGRRPLTV
GLAFSLGHSTVVIAATLGIALTAFALRTHFDAFRDIGGTIGTAVSATFLLALACVNLMILRDVWRRYRRAPAHAHDGAHR
HRRDGLLSRLLRPLFRFVSKSWHMYPIGVLFGLGFDTATEIGLLAIAAAQASQGLPIYTVMLFPALFTAGMTLIDSTDNV
LMIHAYGWAMDDPQRKLLYNASITLVSAIVALAIGGIEAAGLLADKLALTGPVRDALDALGERFGTLGYAIVALFIVCWI
ASILFHRWQRAAGAPAR

Sequences:

>Translated_337_residues
MLSATPALRRLLILYAGLIAANAAVWLWALAVLRAHPLLLGTAAIAYGLGLRHAVDADHIAAIDVATRKLMHDGRRPLTV
GLAFSLGHSTVVIAATLGIALTAFALRTHFDAFRDIGGTIGTAVSATFLLALACVNLMILRDVWRRYRRAPAHAHDGAHR
HRRDGLLSRLLRPLFRFVSKSWHMYPIGVLFGLGFDTATEIGLLAIAAAQASQGLPIYTVMLFPALFTAGMTLIDSTDNV
LMIHAYGWAMDDPQRKLLYNASITLVSAIVALAIGGIEAAGLLADKLALTGPVRDALDALGERFGTLGYAIVALFIVCWI
ASILFHRWQRAAGAPAR
>Mature_337_residues
MLSATPALRRLLILYAGLIAANAAVWLWALAVLRAHPLLLGTAAIAYGLGLRHAVDADHIAAIDVATRKLMHDGRRPLTV
GLAFSLGHSTVVIAATLGIALTAFALRTHFDAFRDIGGTIGTAVSATFLLALACVNLMILRDVWRRYRRAPAHAHDGAHR
HRRDGLLSRLLRPLFRFVSKSWHMYPIGVLFGLGFDTATEIGLLAIAAAQASQGLPIYTVMLFPALFTAGMTLIDSTDNV
LMIHAYGWAMDDPQRKLLYNASITLVSAIVALAIGGIEAAGLLADKLALTGPVRDALDALGERFGTLGYAIVALFIVCWI
ASILFHRWQRAAGAPAR

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 36207; Mature: 36207

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSATPALRRLLILYAGLIAANAAVWLWALAVLRAHPLLLGTAAIAYGLGLRHAVDADHI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHH
AAIDVATRKLMHDGRRPLTVGLAFSLGHSTVVIAATLGIALTAFALRTHFDAFRDIGGTI
HHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GTAVSATFLLALACVNLMILRDVWRRYRRAPAHAHDGAHRHRRDGLLSRLLRPLFRFVSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SWHMYPIGVLFGLGFDTATEIGLLAIAAAQASQGLPIYTVMLFPALFTAGMTLIDSTDNV
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCE
LMIHAYGWAMDDPQRKLLYNASITLVSAIVALAIGGIEAAGLLADKLALTGPVRDALDAL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHH
GERFGTLGYAIVALFIVCWIASILFHRWQRAAGAPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSATPALRRLLILYAGLIAANAAVWLWALAVLRAHPLLLGTAAIAYGLGLRHAVDADHI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHH
AAIDVATRKLMHDGRRPLTVGLAFSLGHSTVVIAATLGIALTAFALRTHFDAFRDIGGTI
HHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
GTAVSATFLLALACVNLMILRDVWRRYRRAPAHAHDGAHRHRRDGLLSRLLRPLFRFVSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
SWHMYPIGVLFGLGFDTATEIGLLAIAAAQASQGLPIYTVMLFPALFTAGMTLIDSTDNV
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCE
LMIHAYGWAMDDPQRKLLYNASITLVSAIVALAIGGIEAAGLLADKLALTGPVRDALDAL
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHH
GERFGTLGYAIVALFIVCWIASILFHRWQRAAGAPAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]