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The map label for this gene is xseA [H]

Identifier: 161523932

GI number: 161523932

Start: 823840

End: 825222

Strand: Direct

Name: xseA [H]

Synonym: Bmul_0752

Alternate gene names: 161523932

Gene position: 823840-825222 (Clockwise)

Preceding gene: 161523927

Following gene: 161523933

Centisome position: 23.89

GC content: 72.96

Gene sequence:

>1383_bases
ATGCTCTCCGACTCTCCTTTTGCCGCACCCGGCGCGACGCGCGGCGGCGACGAAGTGATTCCCGTTTCGGCGCTGAACCG
CGCGATTTCGACGATGCTCGAACGCTCGTTCCCGCTGCTGTGGATCTCGGGCGAAGTATCGAACTTCACGCGCGCGGCGA
GCGGTCACTGGTATTTCTCGATCAAGGATCAGCAGGCGCAGATGCGCTGCGTGATGTTCCGCGGCCGCGCGCAATACGCG
GAGTTCATGCCGCGCGAAGGCGACCGCATCGAAGTGCGCGCGGTCGTCACGATGTACGAGCCGCGCGGCGAGGTGCAGCT
GAATGTCGAGGCCGTGCGGCGCACCGGACAGGGGCGGCTCTACGAGGCGTTCCTGCGGCTGAAGGCGCAGCTCGAGGCCG
AAGGGCTGTTCGCGCCCGAGCGCAAGCGGCCGCTGCCCGCGCACCCGCGCGCGATCGGCATCGTCACGTCGCTGCAGGCC
GCCGCGCTGCGCGACGTGCTGACCACGCTCGCGCGTCGCGCGCCGCATGTCCCCGTGATCGTGTATCCGGCGCCCGTGCA
GGGTGCGGGCGCGGCGGAGAAGCTCGTCGCGGCCGTGCAAACGGCGAACGCGCGGCGCGAGGTCGACGTGCTGCTCGTCT
GTCGCGGCGGCGGCTCGATCGAAGATCTGTGGTCGTTCAACGACGAAGCGCTCGCGCGCGCGATTGCGGCGAGCGAACTG
CCGGTCGTCTGCGGCGTCGGGCACGAAACCGATTTCACGATCGCCGATTTCGCGGCCGACGTGCGCGCGCCGACGCCGAC
CGGCGCGGCCGAGCTCGCGAGCCCGCAGCGCGCGCTGCTGCTGCGCGAACTGGCCGAGCGCGAACGGGCGCTTGCGCGCG
CACTGGCGCGCGGCCTCGAGCAGCGCGCGCAGCAGCTCGACTGGCTCGCGCGCCGGCTCGTGAGCCCGGCCGAACGGCTG
CAGCGGCAACGTGCGCACGTCGGCCAGCTCGCGGTGCGGCTCGCGACGGCCGCCGCGCGCCCGGTGCGCGACGCACGCGC
GCGGTTTGCGCTCGCGCAGTTGCGCTGGCAGCGCGCGCGACCCGATCCCGCGCATGCGCGCCACGTGCTGGCCGGGCTGT
CGCAGCGTCTCGCGGTTGCGCTGCAGCGCCGTCACGAGCGCGATACCGCGCGCGTCGCCGCATGCGCGGCACGGCTCGAG
GTGCTGAGCCCGCAGCGCACGCTCGAGCGCGGTTACGCGGCGCTGATCGATGCGCAGACGGGCCGCGCGGTGCGCGCGCC
GAGCGCGCTGAAACCGCAGCGCCGGCTGACCGTGCATCTCGCCGAAGGCTCGGCCGACGTGTCGCTGGCGGACGTGCAGC
CGCGGCTGACCGATACGATCTGA

Upstream 100 bases:

>100_bases
GAGTGTGGACACTTCGGTGCACGGCGGCGGCGCGGCGTGACGCTGGACGCCGCGCGGATGTCGGACTATCGTGTCGCCGC
CAGCATTCAATCGACCTTCC

Downstream 100 bases:

>100_bases
GCTGGCCTGCGAGCCGACGCGCGAGCGCCGTCGAACGCGTCGCGCGGACGCCGGCGGCGCGGGCACGCGCGCTGCGCGTC
TCGCCCGCGTGCCGCCCGTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLSDSPFAAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYA
EFMPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQA
AALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLVAAVQTANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
PVVCGVGHETDFTIADFAADVRAPTPTGAAELASPQRALLLRELAERERALARALARGLEQRAQQLDWLARRLVSPAERL
QRQRAHVGQLAVRLATAAARPVRDARARFALAQLRWQRARPDPAHARHVLAGLSQRLAVALQRRHERDTARVAACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPSALKPQRRLTVHLAEGSADVSLADVQPRLTDTI

Sequences:

>Translated_460_residues
MLSDSPFAAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYA
EFMPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQA
AALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLVAAVQTANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
PVVCGVGHETDFTIADFAADVRAPTPTGAAELASPQRALLLRELAERERALARALARGLEQRAQQLDWLARRLVSPAERL
QRQRAHVGQLAVRLATAAARPVRDARARFALAQLRWQRARPDPAHARHVLAGLSQRLAVALQRRHERDTARVAACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPSALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
>Mature_460_residues
MLSDSPFAAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYA
EFMPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQA
AALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLVAAVQTANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
PVVCGVGHETDFTIADFAADVRAPTPTGAAELASPQRALLLRELAERERALARALARGLEQRAQQLDWLARRLVSPAERL
QRQRAHVGQLAVRLATAAARPVRDARARFALAQLRWQRARPDPAHARHVLAGLSQRLAVALQRRHERDTARVAACAARLE
VLSPQRTLERGYAALIDAQTGRAVRAPSALKPQRRLTVHLAEGSADVSLADVQPRLTDTI

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=440, Percent_Identity=41.5909090909091, Blast_Score=334, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50356; Mature: 50356

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDSPFAAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFS
CCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCEEEE
IKDQQAQMRCVMFRGRAQYAEFMPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRL
ECCCHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHH
YEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQAAALRDVLTTLARRAPHVPVI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VYPAPVQGAGAAEKLVAAVQTANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
EECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCC
PVVCGVGHETDFTIADFAADVRAPTPTGAAELASPQRALLLRELAERERALARALARGLE
CEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRAQQLDWLARRLVSPAERLQRQRAHVGQLAVRLATAAARPVRDARARFALAQLRWQRAR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
PDPAHARHVLAGLSQRLAVALQRRHERDTARVAACAARLEVLSPQRTLERGYAALIDAQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHEEEECCC
GRAVRAPSALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
CCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCHHHCCC
>Mature Secondary Structure
MLSDSPFAAPGATRGGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFS
CCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCEEEE
IKDQQAQMRCVMFRGRAQYAEFMPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRL
ECCCHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHH
YEAFLRLKAQLEAEGLFAPERKRPLPAHPRAIGIVTSLQAAALRDVLTTLARRAPHVPVI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VYPAPVQGAGAAEKLVAAVQTANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASEL
EECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCC
PVVCGVGHETDFTIADFAADVRAPTPTGAAELASPQRALLLRELAERERALARALARGLE
CEEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRAQQLDWLARRLVSPAERLQRQRAHVGQLAVRLATAAARPVRDARARFALAQLRWQRAR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
PDPAHARHVLAGLSQRLAVALQRRHERDTARVAACAARLEVLSPQRTLERGYAALIDAQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHEEEECCC
GRAVRAPSALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
CCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA