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The map label for this gene is argF [H]

Identifier: 161523923

GI number: 161523923

Start: 815543

End: 816472

Strand: Reverse

Name: argF [H]

Synonym: Bmul_0743

Alternate gene names: 161523923

Gene position: 816472-815543 (Counterclockwise)

Preceding gene: 161523925

Following gene: 161523921

Centisome position: 23.68

GC content: 62.37

Gene sequence:

>930_bases
ATGACCGCCAAAACCATTCGTCACTACCTGCAGTTCAAGGATTTCTCGCTGGAAGACTACGAGTACGTGCTCGAACGCAC
GGGTATCCTGAAGCGCAAGTTCAAGAACTACGAGACCTACCATCCGCTGCACGACCGCACGCTCGCGATGATCTTCGAGA
AGAGCTCGACGCGCACGCGTCTGTCGTTCGAAGCGGGGATCTTCCAGCTCGGCGGCCACGCGGTATTCATGAGCACGCGC
GACACGCAGCTCGGCCGCGGCGAGCCGGTCGAGGATTCCGCGCAGGTCATCTCGCGGATGGTCGACATCATCATGATCCG
CACGTTCGAGCAGGACATCATCCAGCGCTTCGCGGAAAACTCGCGCGTGCCGGTGATCAACGGGCTGACCAACGAATACC
ACCCGTGCCAGGTGCTCGCCGACATCTTCACGTACTACGAGCACCGCGGCCCGATCGCGGGCAAGACCGTCGCATGGGTC
GGCGACGCGAACAACATGCTCTATACGTGGATTCAGGCCGCGCAGATCCTCGGCTTCAAGCTGCGCCTGTCGACGCCGCC
CGGCTACGCGCTCGACATGAAGCTCGTGTCGCCCGACAGCGCACCGTTCTACGAGGTGTTCGACGATCCGAACGAAGCAT
GCAAGGGTGCCGATCTCGTCACGACCGATGTCTGGACGAGCATGGGTTTCGAGGCCGAGAACGAGGCACGGATGAAGGCG
TTTGCCGACTGGTGCGTCGACGAGGAAATGATGGGCCATGCGAATCCGGACGCGCTGTTCATGCACTGCCTGCCCGCGCA
TCGCGGCGAGGAAGTGACGGCCGGCGTGATCGACGGCCCGCAAAGCGTCGTGTGGGACGAAGCGGAAAACCGGCTGCACG
TGCAGAAGGCGCTGATGGAGTTCCTGCTGCTCGGCCGCCTCAAGCACTGA

Upstream 100 bases:

>100_bases
TCAAAGCACGGAAAATCCTTTATGCTGCTTTGAGTTATTCACATCCGACGGCGGCGCCGTCCGGCGTCGCCGCCGGGTGA
AGCCCGCCGTATTTCGTTTC

Downstream 100 bases:

>100_bases
ACGCGCGCGCTGCGCGGCCTGCGCCGCGTGCATCGCATGAAAAACGCCGATCGTCCGATCGGCGTTTCGTTTTGTACGGC
ACGGGAAACCGGTGCGCCCG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWV
GDANNMLYTWIQAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARMKA
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Sequences:

>Translated_309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWV
GDANNMLYTWIQAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARMKA
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH
>Mature_308_residues
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRD
TQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVG
DANNMLYTWIQAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARMKAF
ADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=38.8157894736842, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI18105007, Length=308, Percent_Identity=26.2987012987013, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=36, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=36.6153846153846, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI2367364, Length=309, Percent_Identity=27.831715210356, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=296, Percent_Identity=27.027027027027, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=323, Percent_Identity=33.4365325077399, Blast_Score=196, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6322331, Length=304, Percent_Identity=25, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642586, Length=321, Percent_Identity=26.4797507788162, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35285; Mature: 35153

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAEN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIQAAQILGFK
CCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEE
LRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARMKA
EEECCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCEEEHHHHHHCCCCCCCHHHHHH
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHHCCHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLKH
HHHHHHCCC
>Mature Secondary Structure 
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAEN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIQAAQILGFK
CCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEE
LRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARMKA
EEECCCCCCEEEEEEECCCCCCCHHCCCCHHHHHCCCCEEEHHHHHHCCCCCCCHHHHHH
FADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHHCCHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLKH
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA