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The map label for this gene is glpR [H]

Identifier: 161523803

GI number: 161523803

Start: 681974

End: 682858

Strand: Reverse

Name: glpR [H]

Synonym: Bmul_0623

Alternate gene names: 161523803

Gene position: 682858-681974 (Counterclockwise)

Preceding gene: 161523807

Following gene: 161523802

Centisome position: 19.8

GC content: 66.21

Gene sequence:

>885_bases
ATGAATCCATGTGCTTTTCGCATGAATCGGGTGTACCCGCGTGCCGGCGGCGCGACGGACACCCTTACAATATCCGCTTC
GTTTTCACGCCCCCGACCGTCGAACATGAGCAGAGATCCCCGCCTCACCCTGAACGCGCGCCAGCAGGAATTGCTCGAAT
GGGTGCAGCGCGACGGCTTCGTGACCGTCGACGATCTCGCCGCGCATTTCGCCGTCACGCCGCAGACGATCCGCCGCGAC
GTGAACTGGCTCGCCGACCTGAACCTGCTGCGCCGCTATCACGGCGGCGCGAGCCTGCCGACCAGCTCAGAGAACGTGTC
GTACACCGCGCGGCAGCGCATGTTCCACGACGAGAAGCGGCGCATCGCGGCGCTCGCGGCGTCGCACATCCCCGATCAGG
CGTCGCTCTTCATCAACCTCGGCACGACCACCGAGGAAGTCGCGCGCGCGCTGAACCGCCATCACGGGCTGCGCGTGATC
ACGAACAACCTGAACGTCGCGTCGATGATGAGCGGCTACCCCGACTGCGAGGTGCTGATCACCGGCGGCATCGTGCGGCC
CTGGGACAAGGGCATCGTCGGCGAACTCGCGATCGACTTCATCCGGCAGTTCAAGGTCGACTACGCGATCATCGGCACGT
CGGCGATCGAGGCCGACGGAACGCTGCGCGACTTCGATACGCGCGAGGTGCGCGTCGCGGAGGCGATCATCGAGCATGCG
CGCACGGTCTATCTCGTCGCCGATCATTCGAAGATCGGGCGGCCGGCGCTCGTGCGCCAGGGCCATCTGAGCCAGGTCCA
CGCGCTGTTCACCGACAAGCCGCTGCCGGCCGACATGGCCGATACGATCGCCGCGGCCGGCACGCAGGTGTACGTCGCCG
AATGA

Upstream 100 bases:

>100_bases
CATCGGTCTACCTCGTCGAAAACGAATGGAATGCGCCCCCGCGCGCGGGGAATCCGCCATTGCATCGCGATCGGCGTAAT
CGCACAAATTCATTTGTGAA

Downstream 100 bases:

>100_bases
TCGGCGCGATGCTGCGCCGCATCGCGAACTTCAAGTGAAATCAAGAAGTTCGCCGCGCGGCCGAACCGCTTGTGGATGGC
CTGCCTGTCAAACGGAAAAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNPCAFRMNRVYPRAGGATDTLTISASFSRPRPSNMSRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRD
VNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLRVI
TNNLNVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIIEHA
RTVYLVADHSKIGRPALVRQGHLSQVHALFTDKPLPADMADTIAAAGTQVYVAE

Sequences:

>Translated_294_residues
MNPCAFRMNRVYPRAGGATDTLTISASFSRPRPSNMSRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRD
VNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLRVI
TNNLNVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIIEHA
RTVYLVADHSKIGRPALVRQGHLSQVHALFTDKPLPADMADTIAAAGTQVYVAE
>Mature_294_residues
MNPCAFRMNRVYPRAGGATDTLTISASFSRPRPSNMSRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRD
VNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLRVI
TNNLNVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIIEHA
RTVYLVADHSKIGRPALVRQGHLSQVHALFTDKPLPADMADTIAAAGTQVYVAE

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=47.2573839662447, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI87082344, Length=239, Percent_Identity=41.4225941422594, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=29.5652173913043, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789519, Length=263, Percent_Identity=26.615969581749, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=27.3092369477912, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=28.6290322580645, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=235, Percent_Identity=29.7872340425532, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI226510968, Length=231, Percent_Identity=29.4372294372294, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787063, Length=256, Percent_Identity=27.34375, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=25.296442687747, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 32615; Mature: 32615

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPCAFRMNRVYPRAGGATDTLTISASFSRPRPSNMSRDPRLTLNARQQELLEWVQRDGF
CCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCC
VTVDDLAAHFAVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKR
EEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
RIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLRVITNNLNVASMMSGYPDCEVLI
HHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCEEEE
TGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIIEHA
ECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHCC
RTVYLVADHSKIGRPALVRQGHLSQVHALFTDKPLPADMADTIAAAGTQVYVAE
CEEEEEECCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MNPCAFRMNRVYPRAGGATDTLTISASFSRPRPSNMSRDPRLTLNARQQELLEWVQRDGF
CCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCC
VTVDDLAAHFAVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKR
EEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
RIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLRVITNNLNVASMMSGYPDCEVLI
HHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCEEEE
TGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIIEHA
ECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHCC
RTVYLVADHSKIGRPALVRQGHLSQVHALFTDKPLPADMADTIAAAGTQVYVAE
CEEEEEECCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]