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The map label for this gene is lptA [H]

Identifier: 161523706

GI number: 161523706

Start: 574733

End: 575398

Strand: Reverse

Name: lptA [H]

Synonym: Bmul_0526

Alternate gene names: 161523706

Gene position: 575398-574733 (Counterclockwise)

Preceding gene: 161523707

Following gene: 161523705

Centisome position: 16.69

GC content: 68.32

Gene sequence:

>666_bases
ATGAACGAACCGTTCCCTCGACAGAATTCCGGCGGCGCTGCGCGCGCCGTCCGCGCCGCGCTCGCCGCGACGCTCGTCGC
CCTGCCCCTCGTCGGCCTGGCGCCGCTCGCCCACGCCGAGAAGGCCGACCAGAACAAGCCGATCAACGTCGAGGCGGACA
ACCTGACCTATGACGACCTGAAGCAGGTCACCGTCGCCACCGGCAACGTCGTGATCACGAAGGGCACGATCAAGATCACC
GGCGATCGCGTCGAAGTGCGCCAGGATCCGGAGGGCTATCAGTACGCGACGTCGTTCGGCAGCGGCAAGAAGCACGCGAC
GTTCCGCCAGAAGCGCGAAGGTCTCGACGAATACATCGACGGCGACGCCGAGCGCATCGACTACGACGGCAAGCAGGATC
TCACCACGCTGACGACCGCCGCGACCGTGCGTCGCCTGCAGGGCACGTCGACGATCGCCGACACCGTGCACGGCAGCGTG
ATCACGTACGACGGCCAGCACGACTTCTACACCGCGAAGGGCGGCAAGGACGTCGCGGCGCCCGGCAACCCGAACGGTCG
CGTGCGCGCGATGCTGTCGCCGAAGAACGGCGGCCCGGGCCCGATGAACGGTGCGCCGGCGAAGCTGTCGCCGTCGACCA
CGATCCAGGGAGCGCCCGGTCAATGA

Upstream 100 bases:

>100_bases
TCATCGAGCTTTACGGCAACGTGCGCGGCACGATCGCCGCGTCGGACGCGTCCGGCGGCTCGAAAGGTCAACCCAAGTGA
CGCTTCCCTCACGTGACTGC

Downstream 100 bases:

>100_bases
ACGCGCTCCCGAATCGCCAGCCGGCCGGCACCACGAGCTCGCTCGTCGTCCGCAACCTGAAGAAGCGCTACGGCTCGCGC
ACGGTCGTCAAGGACGTCTC

Product: lipopolysaccharide transport periplasmic protein LptA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNEPFPRQNSGGAARAVRAALAATLVALPLVGLAPLAHAEKADQNKPINVEADNLTYDDLKQVTVATGNVVITKGTIKIT
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSV
ITYDGQHDFYTAKGGKDVAAPGNPNGRVRAMLSPKNGGPGPMNGAPAKLSPSTTIQGAPGQ

Sequences:

>Translated_221_residues
MNEPFPRQNSGGAARAVRAALAATLVALPLVGLAPLAHAEKADQNKPINVEADNLTYDDLKQVTVATGNVVITKGTIKIT
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSV
ITYDGQHDFYTAKGGKDVAAPGNPNGRVRAMLSPKNGGPGPMNGAPAKLSPSTTIQGAPGQ
>Mature_221_residues
MNEPFPRQNSGGAARAVRAALAATLVALPLVGLAPLAHAEKADQNKPINVEADNLTYDDLKQVTVATGNVVITKGTIKIT
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSV
ITYDGQHDFYTAKGGKDVAAPGNPNGRVRAMLSPKNGGPGPMNGAPAKLSPSTTIQGAPGQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 23271; Mature: 23271

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPFPRQNSGGAARAVRAALAATLVALPLVGLAPLAHAEKADQNKPINVEADNLTYDDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
KQVTVATGNVVITKGTIKITGDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYID
HEEEEECCCEEEEECEEEEECCEEEEEECCCCCEEEHHCCCCCCCHHHHHHHHHHHHHHC
GDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSVITYDGQHDFYTAKGGKDVAA
CCHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCEEECCCCCCCCC
PGNPNGRVRAMLSPKNGGPGPMNGAPAKLSPSTTIQGAPGQ
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure
MNEPFPRQNSGGAARAVRAALAATLVALPLVGLAPLAHAEKADQNKPINVEADNLTYDDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
KQVTVATGNVVITKGTIKITGDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYID
HEEEEECCCEEEEECEEEEECCEEEEEECCCCCEEEHHCCCCCCCHHHHHHHHHHHHHHC
GDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSVITYDGQHDFYTAKGGKDVAA
CCHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCEEECCCCCCCCC
PGNPNGRVRAMLSPKNGGPGPMNGAPAKLSPSTTIQGAPGQ
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]