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The map label for this gene is yjcE [H]

Identifier: 161523538

GI number: 161523538

Start: 395477

End: 397372

Strand: Reverse

Name: yjcE [H]

Synonym: Bmul_0358

Alternate gene names: 161523538

Gene position: 397372-395477 (Counterclockwise)

Preceding gene: 161523541

Following gene: 161523536

Centisome position: 11.52

GC content: 68.09

Gene sequence:

>1896_bases
ATGAACCCTCGGTTTATCCGGCCTGCGCCGGACGGCGAGCAAGCATCAAGCAAGCTCCGTGCAAGCGTCGATCACGCGCG
CGCCGCACGGTGCACGCGGTGCTGCACCAGCACGGCGCAACGCAGTTGCACCGTTTGCGTGCATCCGCACCGGCGCACCG
GAGCGCAGCGCTCGCGCGAGCACGCTACACTCCGTACGGTCGTTTCATTCCCTGCCTTTGCCGTATCGATGGAAATCGTC
TTCACCGTCCTCATCCTGCTGCTCACCGTCGCGCTGTCCGGCGCGCTCACGCGCGTGTTACCGTTGCGGCTGCCGCTGCC
GCTGATGCAGATCGCCTTCGGCGCCGCGCTCGCGTGGCCGCAACTGAACCTCCATGTGACGTTCGACCCTGAAATCTTCA
TGCTGCTGTTCATTCCGCCGCTGCTGTTCGCAGACGGCTGGCGGATTCCGAAACGCGAGCTGTATCTGCAGCGGCGCGCG
ATCCTGATGCTCGCGTTCGGCCTCGTGTTCATGACGGTACTCGCCGTCGGCTACTTCGCGCATTGGCTGATTCCCGAGTT
GCCGCTGCCGATCGCGTTCGCGCTCGCGGCCGTGCTCTCGCCGACCGATGCCGTCGCGCTGTCGGGCATCGCCGGAAAGG
GCCGGATCCCGCCGCAACTGATGCACATCCTCGAAGGCGAGGCGCTGATGAACGACGCGTCGGGCCTCGTCGCGCTGAAG
TTCGCGATCGCCGCCGCGCTCACCGGCGTGTTCTCGCTGCGCGACGCGTCGTTGACGTTCGTCGTCGTCGCGGCCGGCGG
GCTCGCGACGGGCGCGGCCGTGTCCTGGCTGTTCAGCGCGCTGTCGACGCGCTTCCTCAATGCCGAGCAGGAAGGCGATC
CGGCGCCCGGCATCGTGATGACGCTGCTCGTGCCGTTCGCCGCGTACCTGTTCGCCGAGCACTTCGATCTGTCCGGCGTG
CTCGCGGCCGTGTCGGCCGGGATGATGATGAATTACACGAGCTTCTCGCGCAAAAGCACGGTCGCGTCGCGCGTGCGCGC
GGAAAGCACGTGGGCGATGATCGAGTTCGTGTTCAACGGCATGGTGTTCATCATGCTCGGGCTGCAGCTGCCGCACATCA
TCGGCCGCGCGCTCGTCGAGGCACACCATACGAGCGACGCGCTGGTCGGCCGCATGATCTTCAACGTGGGCGCGATGATG
CTCTCGCTGTATGCGATCCGCTTTCTGTGGGTATGGCTGCTGCGCTGGTTCGCGAGCCGCCGCGCAGCACGGCAGGGCCT
CGCGGGCACGATGGCCGGCGTGCGCACGATCGCGGTGATGACGGTCGGCGGCGTGCGCGGCGCGGTCACGCTCGCCGGCG
TGCTGTCGATTCCGGTCGCGCTGTCGAGCGGCGCGCCGCTGCCGGGCCGCGATACCGCGATCTTCATCGCGTCGGCCGTG
ATTCTCGGTTCGCTGATCGTCGCGGTGATCGGCCTGCCGCTGCTGCTGCGCGGCGTGCGCACGACGCGCAATCCGCTCGC
CGGCGAGGAACGCGCGGCGCGCGCCGCGGCCGCTCAAGCCGCGATCCGCGCGATCGACGCGTCGCACGACGCGATCTCGG
CCGAACTCGACGAATCGGGCGCCGCGCGCTGCGCGGACATCTCCGCGCGCGTGATGGATCAGTATCGGCGCCGGCTCGCC
GCGCTCGCCGAGGACGGCCCGACGCCGCGCGCCGAAGCGAAGCAGGCGGAAACGATGGAGCTGCAGATGCGGATCGCGGC
CGTGCGCGCGGAGCGCTCGATGCTGTATCGGCTGCGTACCGAAAGCAAGATCTCCGACGAGACGCTGACGAAGCTGATCC
GCGAAATCGATCTGTCGGAAACCGCGCTGTCGACGCGCAAGAAAGGAATCGTCTGA

Upstream 100 bases:

>100_bases
GCTCCTGTTGCTCGGTCGTCATGCGTTCCTCCTGAAATCGGTCTGCATCGGCAACGCGGCGGCTGACGAACCGGACGGCG
CGCGGCATCGGCCCATGTCG

Downstream 100 bases:

>100_bases
ACGGCGACGGGCGGCACGCGCCGCGCCCGCCATGAAAAAACGGCGATGCCGCACGCGCGCATCGCCGTTTTTCGTTTGCG
GCGCGCCGGCGCCGCGCGCC

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MNPRFIRPAPDGEQASSKLRASVDHARAARCTRCCTSTAQRSCTVCVHPHRRTGAQRSREHATLRTVVSFPAFAVSMEIV
FTVLILLLTVALSGALTRVLPLRLPLPLMQIAFGAALAWPQLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRA
ILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALK
FAIAAALTGVFSLRDASLTFVVVAAGGLATGAAVSWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHFDLSGV
LAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVEAHHTSDALVGRMIFNVGAMM
LSLYAIRFLWVWLLRWFASRRAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSSGAPLPGRDTAIFIASAV
ILGSLIVAVIGLPLLLRGVRTTRNPLAGEERAARAAAAQAAIRAIDASHDAISAELDESGAARCADISARVMDQYRRRLA
ALAEDGPTPRAEAKQAETMELQMRIAAVRAERSMLYRLRTESKISDETLTKLIREIDLSETALSTRKKGIV

Sequences:

>Translated_631_residues
MNPRFIRPAPDGEQASSKLRASVDHARAARCTRCCTSTAQRSCTVCVHPHRRTGAQRSREHATLRTVVSFPAFAVSMEIV
FTVLILLLTVALSGALTRVLPLRLPLPLMQIAFGAALAWPQLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRA
ILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALK
FAIAAALTGVFSLRDASLTFVVVAAGGLATGAAVSWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHFDLSGV
LAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVEAHHTSDALVGRMIFNVGAMM
LSLYAIRFLWVWLLRWFASRRAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSSGAPLPGRDTAIFIASAV
ILGSLIVAVIGLPLLLRGVRTTRNPLAGEERAARAAAAQAAIRAIDASHDAISAELDESGAARCADISARVMDQYRRRLA
ALAEDGPTPRAEAKQAETMELQMRIAAVRAERSMLYRLRTESKISDETLTKLIREIDLSETALSTRKKGIV
>Mature_631_residues
MNPRFIRPAPDGEQASSKLRASVDHARAARCTRCCTSTAQRSCTVCVHPHRRTGAQRSREHATLRTVVSFPAFAVSMEIV
FTVLILLLTVALSGALTRVLPLRLPLPLMQIAFGAALAWPQLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRA
ILMLAFGLVFMTVLAVGYFAHWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALK
FAIAAALTGVFSLRDASLTFVVVAAGGLATGAAVSWLFSALSTRFLNAEQEGDPAPGIVMTLLVPFAAYLFAEHFDLSGV
LAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVEAHHTSDALVGRMIFNVGAMM
LSLYAIRFLWVWLLRWFASRRAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSSGAPLPGRDTAIFIASAV
ILGSLIVAVIGLPLLLRGVRTTRNPLAGEERAARAAAAQAAIRAIDASHDAISAELDESGAARCADISARVMDQYRRRLA
ALAEDGPTPRAEAKQAETMELQMRIAAVRAERSMLYRLRTESKISDETLTKLIREIDLSETALSTRKKGIV

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI5454070, Length=291, Percent_Identity=23.3676975945017, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI110227626, Length=267, Percent_Identity=24.7191011235955, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI294997330, Length=267, Percent_Identity=24.7191011235955, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI27734935, Length=268, Percent_Identity=24.2537313432836, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI41872703, Length=348, Percent_Identity=23.8505747126437, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI14211919, Length=262, Percent_Identity=24.0458015267176, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI148727259, Length=259, Percent_Identity=24.7104247104247, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI1790501, Length=555, Percent_Identity=47.7477477477478, Blast_Score=475, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71980847, Length=392, Percent_Identity=26.0204081632653, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71999817, Length=457, Percent_Identity=24.2888402625821, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71999819, Length=457, Percent_Identity=24.2888402625821, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71999821, Length=423, Percent_Identity=24.3498817966903, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71990932, Length=392, Percent_Identity=25.2551020408163, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71987537, Length=567, Percent_Identity=22.0458553791887, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71987535, Length=567, Percent_Identity=22.0458553791887, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71990924, Length=392, Percent_Identity=25.2551020408163, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25150332, Length=368, Percent_Identity=23.3695652173913, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=257, Percent_Identity=24.9027237354086, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221473215, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281364513, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221473222, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221473212, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360447, Length=312, Percent_Identity=23.3974358974359, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 67953; Mature: 67953

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRFIRPAPDGEQASSKLRASVDHARAARCTRCCTSTAQRSCTVCVHPHRRTGAQRSRE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCHHHHHH
HATLRTVVSFPAFAVSMEIVFTVLILLLTVALSGALTRVLPLRLPLPLMQIAFGAALAWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
QLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFA
CEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALK
HHHHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHH
FAIAAALTGVFSLRDASLTFVVVAAGGLATGAAVSWLFSALSTRFLNAEQEGDPAPGIVM
HHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
TLLVPFAAYLFAEHFDLSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVFIMLGLQLPHIIGRALVEAHHTSDALVGRMIFNVGAMMLSLYAIRFLWVWLLRWFASR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSSGAPLPGRDTAIFIASAV
HHHHHCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ILGSLIVAVIGLPLLLRGVRTTRNPLAGEERAARAAAAQAAIRAIDASHDAISAELDESG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
AARCADISARVMDQYRRRLAALAEDGPTPRAEAKQAETMELQMRIAAVRAERSMLYRLRT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESKISDETLTKLIREIDLSETALSTRKKGIV
CCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNPRFIRPAPDGEQASSKLRASVDHARAARCTRCCTSTAQRSCTVCVHPHRRTGAQRSRE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCHHHHHH
HATLRTVVSFPAFAVSMEIVFTVLILLLTVALSGALTRVLPLRLPLPLMQIAFGAALAWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
QLNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFA
CEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HWLIPELPLPIAFALAAVLSPTDAVALSGIAGKGRIPPQLMHILEGEALMNDASGLVALK
HHHHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHH
FAIAAALTGVFSLRDASLTFVVVAAGGLATGAAVSWLFSALSTRFLNAEQEGDPAPGIVM
HHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
TLLVPFAAYLFAEHFDLSGVLAAVSAGMMMNYTSFSRKSTVASRVRAESTWAMIEFVFNG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVFIMLGLQLPHIIGRALVEAHHTSDALVGRMIFNVGAMMLSLYAIRFLWVWLLRWFASR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAARQGLAGTMAGVRTIAVMTVGGVRGAVTLAGVLSIPVALSSGAPLPGRDTAIFIASAV
HHHHHCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ILGSLIVAVIGLPLLLRGVRTTRNPLAGEERAARAAAAQAAIRAIDASHDAISAELDESG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
AARCADISARVMDQYRRRLAALAEDGPTPRAEAKQAETMELQMRIAAVRAERSMLYRLRT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESKISDETLTKLIREIDLSETALSTRKKGIV
CCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]