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The map label for this gene is epiC [H]

Identifier: 161510036

GI number: 161510036

Start: 1950508

End: 1951752

Strand: Reverse

Name: epiC [H]

Synonym: USA300HOU_1813

Alternate gene names: 161510036

Gene position: 1951752-1950508 (Counterclockwise)

Preceding gene: 161510037

Following gene: 161510035

Centisome position: 67.94

GC content: 28.76

Gene sequence:

>1245_bases
ATGATTGATATGAATCTAATATTGAAGAAGAAGTTTCAAGAGATTTCAGAAGTAGATGATTTCATTTCAAAAGCATCTAC
TGAAACCGATTATTTTGAACCTTCAACTTTATCACATGGTATACCAGGTATCATTTTGTTTTTAGATGCTTATCAAAAAG
TTTTCGATATTAATACTGAGCAAATTGTGCATAAGTACATCATGAAATTAGCACCATATTTACAGAGTGGTCAATATAAC
AATTCTTTGTTTGGTGGACTTTCAGGTATTGCATTTTCAATGGATTTAGCATCGCAAAATGGCAAAAATTATCAAAATAT
TTTAAATAATATTGATGGTCACATTGTAAATGAAATAGAAAATAAATTTGATCAAATATTACAAGAACCATTAAATCCAT
TAAATTATGATACTGTCAGTGGATTAGCTGGGATAGGGAGATATTTGCTAAATAGAGTAGATGAGAATGAATTTAATGTT
AAAGCATTAAAAAGCATATTAGTATACTTTAAAGATATTCAATATTCTAAAAATAGCTGGGTAGTCCCACAAGAAAGTCA
ATTTTTAGAGTCTGATAAAAATTATTTTACTGAAGGTAATATCAATCTTGGCCTTGCACATGGAGTGCTAGGACCGATGT
CTTTATTTGCATTATGCGTGATTAAAGGAATTACGATTGAAAATCATCAGCACATATTAAAAGACATGTACAAATTTATC
ATGGACGAAAAATTTTGTAACCACGAAAGATGGTTGCAGCGTTACGATTTAATTTCTGAACGTAATCATTTCAATTTTAT
TCGGAATGGTTGGTGTTATGGCAATACGGGTGTAATGACGACGTTGTTTTTAATCGGCCAAGCATTACAAGATGATGAAA
TAATTAAAATGTCTAAAAAAGTGATGCTACAAGTAGTAAATGATAAAGATGAAAATTTAATAAGTCCAACTATTTGTCAT
GGATTGTCATCACAAATATTAATGTTAACAATTATGAATTTGAATTTTGAATTAAATGAAGTGTCTGATTATATCACTGT
ATTAATAAATAAACTGATTTCTCATTATAAGGAAGATTATCTGGTGAATTTTATAGACATTAATGAAAATAAGCAAGATG
TATTTAAAAGTAGGAAAGTTGGCCTTTTAGAAGGTGAATTAGGGGTCTATCTAACATTGATGACACTGAAAAATACAAAA
ATTCTCAATGAAAAAAATTGGACCAATGCGTTTTTAATTAGCTGA

Upstream 100 bases:

>100_bases
TGCAATCGAATATTTGGCATTGATAAGGATCAAGAAACATTTGTTTTATCTATTGTAAAAGAAATTGTTAAAACTCAAAA
GCATTGGTGTGGTGACAAAA

Downstream 100 bases:

>100_bases
ATGGAGGCGTATATCATGGGAGAAAATGTATTGATTTGTTTGTGTGGCTCAGTTAATAGTATCAATATTAGCCACTATAT
TATTGAATTAAAATCAAAAT

Product: lantibiotic epidermin biosynthesis protein EpiC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTEQIVHKYIMKLAPYLQSGQYN
NSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIENKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNV
KALKSILVYFKDIQYSKNSWVVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKKVMLQVVNDKDENLISPTICH
GLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDYLVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTK
ILNEKNWTNAFLIS

Sequences:

>Translated_414_residues
MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTEQIVHKYIMKLAPYLQSGQYN
NSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIENKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNV
KALKSILVYFKDIQYSKNSWVVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKKVMLQVVNDKDENLISPTICH
GLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDYLVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTK
ILNEKNWTNAFLIS
>Mature_414_residues
MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTEQIVHKYIMKLAPYLQSGQYN
NSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIENKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNV
KALKSILVYFKDIQYSKNSWVVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKKVMLQVVNDKDENLISPTICH
GLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDYLVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTK
ILNEKNWTNAFLIS

Specific function: Involved in the post-translational modification of the lantibiotic epidermin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spaC and L.lactis nisC [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020406
- InterPro:   IPR007822 [H]

Pfam domain/function: PF05147 LANC_like [H]

EC number: NA

Molecular weight: Translated: 47646; Mature: 47646

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHH
QIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIE
HHHHHHHHHHHHHHHCCCCCCCHHHCHHHHHEEEHHHHCCCCCHHHHHHCCCCHHHHHHH
NKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSW
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
CCCCHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKK
HHHHHCCHHHHHHHHHHHHCCCCCHHHHCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHH
VMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDY
HHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS
EEEEEECCCCHHHHHHHHCCCEEECCCCEEEEEEEECCCEEECCCCCCCEEEEC
>Mature Secondary Structure
MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHH
QIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIE
HHHHHHHHHHHHHHHCCCCCCCHHHCHHHHHEEEHHHHCCCCCHHHHHHCCCCHHHHHHH
NKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSW
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFI
CCCCHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
MDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKK
HHHHHCCHHHHHHHHHHHHCCCCCHHHHCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHH
VMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDY
HHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS
EEEEEECCCCHHHHHHHHCCCEEECCCCEEEEEEEECCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1740156 [H]