Click here to switch to the map view.

The map label for this gene is lytA [H]

Identifier: 161509661

GI number: 161509661

Start: 1562424

End: 1563878

Strand: Reverse

Name: lytA [H]

Synonym: USA300HOU_1432

Alternate gene names: 161509661

Gene position: 1563878-1562424 (Counterclockwise)

Preceding gene: 161509662

Following gene: 161509660

Centisome position: 54.44

GC content: 35.53

Gene sequence:

>1455_bases
ATGTTGATAACAAAAAACCAAGCAGAAAAATGGTTTGATAATTCATTAGGGAAGCAGTTCAATCCTGATTTGTTTTATGG
ATTTCAGTGTTATGATTACGCCAATATGTTCTTTATGTTAGCGACAGGCGAAAGGCTGCAAGGTTTATATGCTTATAATA
TCCCGTTTGATAATAAAGCAAAGATTGAAAAATATGGTCAAATAATTAAAAACTATGACAGCTTTTTACCGCAAAAGTTG
GATATTGTCGTTTTCCCGTCAAAGTATGGTGGCGGAGCTGGACACGTTGAAATTGTTGAGAGCGCAAATTTAAACACTTT
CACATCATTTGGTCAAAACTGGAACGGTAAAGGTTGGACTAATGGCGTTGCGCAACCTGGTTGGGGTCCTGAAACTGTGA
CAAGACATGTTCATTATTATGACAATCCAATGTATTTTATTAGGTTAAACTTCCCTAACAACTTAAGCGTTGGCAATAAA
GCTAAAGGTATTATTAAGCAAGCGACTACAAAAAAAGAGGCAGTAATTAAACCTAAAAAAATTATGCTTGTAGCCGGTCA
TGGTTATAACGATCCTGGAGCAGTAGGAAACGGAACAAACGAACGCGATTTTATACGTAAATATATAACGCCTAATATCG
CTAAGTATTTAAGACATGCAGGACATGAAGTTGCATTATACGGTGGCTCAAGTCAATCACAAGATATGTATCAAGATACT
GCATACGGTGTTAATGTAGGCAATAAAAAAGATTATGGCTTATATTGGGTTAAATCACAGGGGTATGACATTGTTCTAGA
AATACATTTAGACGCAGCAGGAGAAAGCGCAAGTGGTGGGCATGTTATTATCTCAAGTCAATTCAATGCAGATACTATTG
ATAAAAGTATACAAGATGTTATTAAAAATAATTTAGGACAAATAAGAGGTGTAACACCTCGTAACGATTTACTAAATGTT
AATGTATCAGCAGAAATAAATATCAATTATCGCTTATCTGAATTAGGTTTTATTACTAATAAAAATGATATGGATTGGAT
TAAGAAAAATTACGACTTGTACTCTAAACTAATAGCTGGTGCGATTCATGGTAAGCCAATTGGTGGAGTGGTAGCTAGTG
AGGTCAAAGCGCCAGTTAAAAACGAAAAGAATCCGCCAGTGCCAGCAGGTTATACACTCGATAAGAATAATGTCCCTTAT
AAAAAAGAACAAGGCAATTACACAGTAGCTAATGTTAAAGGTAATAATGTAAGAGACGGTTATTCAACTAATTCAAGAAT
TACAGGGGTATTACCCAACAACACAACAATTACGTATGACGGTGCATATTGTATTAATGGTTATAGATGGATTACTTATA
TTGCTAATAGTGGACAACGTCGCTATATTGCGACCGGAGAGGTAGACATAGCAGGCAACCGAATAAGCAGTTTTGGTAAG
TTTAGTGCAGTTTGA

Upstream 100 bases:

>100_bases
GAAAGTAAATATAGAAAAGCAACAGGGCAAGCGCCAATTAAAGAAGTAATGACACCTACGAATATGAACGACACAAATGA
TTTAGGGTAGGTGTTGACCA

Downstream 100 bases:

>100_bases
TAATTGTATATGATGAATCTTAGGCAGGTACTTCGGTACTTGCCTATTATTTAAAATTAATAAACAGTTAATTTTTACAT
GAATATATTAAATTTTAAAA

Product: bacteriophage amidase

Products: NA

Alternate protein names: N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKAKIEKYGQIIKNYDSFLPQKL
DIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNK
AKGIIKQATTKKEAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNV
NVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGVVASEVKAPVKNEKNPPVPAGYTLDKNNVPY
KKEQGNYTVANVKGNNVRDGYSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDIAGNRISSFGK
FSAV

Sequences:

>Translated_484_residues
MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKAKIEKYGQIIKNYDSFLPQKL
DIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNK
AKGIIKQATTKKEAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNV
NVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGVVASEVKAPVKNEKNPPVPAGYTLDKNNVPY
KKEQGNYTVANVKGNNVRDGYSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDIAGNRISSFGK
FSAV
>Mature_484_residues
MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKAKIEKYGQIIKNYDSFLPQKL
DIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNK
AKGIIKQATTKKEAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNV
NVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGVVASEVKAPVKNEKNPPVPAGYTLDKNNVPY
KKEQGNYTVANVKGNNVRDGYSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDIAGNRISSFGK
FSAV

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase C51 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR007921
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01510 Amidase_2; PF05257 CHAP; PF08460 SH3_5 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 53781; Mature: 53781

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKA
CEECCCCHHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCHHCCEEEEECCCCCCH
KIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWT
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCC
NGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNKAKGIIKQATTKKEAVIKPKK
CCCCCCCCCHHHHEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHEECCEE
IMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
EEEEECCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDV
HCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHH
IKNNLGQIRGVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAG
HHCCHHHEECCCCCCCEEEEEEEEEEEEEEEEHHCCEEECCCCHHHHHHHHHHHHHHHHH
AIHGKPIGGVVASEVKAPVKNEKNPPVPAGYTLDKNNVPYKKEQGNYTVANVKGNNVRDG
HHCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCEECCCCEEEEEECCCCCCCC
YSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDIAGNRISSFGK
CCCCCEEEEECCCCCEEEECCEEEECCEEEEEEEECCCCEEEEEECCEEECCCCCCCCCC
FSAV
CCCC
>Mature Secondary Structure
MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMLATGERLQGLYAYNIPFDNKA
CEECCCCHHHHHHHHCCCCCCCCEEEEEEEEECCCEEEEEECCCHHCCEEEEECCCCCCH
KIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWT
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCC
NGVAQPGWGPETVTRHVHYYDNPMYFIRLNFPNNLSVGNKAKGIIKQATTKKEAVIKPKK
CCCCCCCCCHHHHEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHEECCEE
IMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDT
EEEEECCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCHHHHHH
AYGVNVGNKKDYGLYWVKSQGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDV
HCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHH
IKNNLGQIRGVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAG
HHCCHHHEECCCCCCCEEEEEEEEEEEEEEEEHHCCEEECCCCHHHHHHHHHHHHHHHHH
AIHGKPIGGVVASEVKAPVKNEKNPPVPAGYTLDKNNVPYKKEQGNYTVANVKGNNVRDG
HHCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCEECCCCEEEEEECCCCCCCC
YSTNSRITGVLPNNTTITYDGAYCINGYRWITYIANSGQRRYIATGEVDIAGNRISSFGK
CCCCCEEEEECCCCCEEEECCEEEECCEEEEEEEECCCCEEEEEECCEEECCCCCCCCCC
FSAV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1677905 [H]