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The map label for this gene is engA [H]

Identifier: 161509642

GI number: 161509642

Start: 1544387

End: 1545697

Strand: Reverse

Name: engA [H]

Synonym: USA300HOU_1412

Alternate gene names: 161509642

Gene position: 1545697-1544387 (Counterclockwise)

Preceding gene: 161509643

Following gene: 161509641

Centisome position: 53.8

GC content: 35.24

Gene sequence:

>1311_bases
ATGACTAAACCTATAGTAGCTATTGTAGGTAGGCCTAATGTAGGTAAATCTACAATTTTTAATAGAATAGTTGGAGAACG
TGTTTCGATTGTGGAAGACACGCCAGGTGTAACACGAGATCGTATTTATTCTTCAGGTGAATGGTTAACACATGATTTCA
ATATTATTGATACAGGTGGTATTGAAATTGGTGATGCACCATTCCAAACACAAATTAGAGCGCAGGCAGAAATCGCCATA
GATGAAGCGTATGTTATTATTTTTATGGTTAACGTGCGTGAAGGATTGACACAAAGCGATGAAATGGTCGCTCAAATTTT
ATACAAATCTAAAAAACCGGTCGTATTAGCGGTTAACAAAGTAGATAATATGGAAATGCGTACAGACGTGTATGATTTCT
ATTCATTAGGATTTGGTGAACCGTATCCGATATCAGGGTCACATGGTTTAGGTCTTGGTGACTTGTTAGATGCAGTTGTT
TCTCATTTTGGTGAAGAGGAAGAAGATCCTTATGATGAAGATACAATTCGACTATCCATTATTGGACGACCAAACGTAGG
TAAATCAAGTTTAGTAAATGCTATTTTAGGTGAAGATCGCGTTATCGTTTCTAATGTTGCAGGGACAACGAGAGACGCTA
TTGATACAGAGTATAGTTATGATGGACAAGATTATGTTTTAATCGATACTGCTGGTATGCGTAAAAAAGGAAAAGTATAT
GAATCAACTGAGAAATATTCAGTATTAAGAGCTTTAAAAGCGATTGAACGTTCAAATGTTGTTTTAGTGGTCATAGATGC
AGAACAAGGCATCATTGAACAAGATAAACGTGTTGCAGGATATGCACATGAACAAGGTAAAGCAGTCGTGATTGTCGTAA
ATAAATGGGATACTGTGGAAAAAGATAGTAAAACGATGAAGAAATTTGAAGATGAAGTACGTAAAGAATTCCAATTTTTA
GATTATGCACAAATTGCTTTTGTGTCTGCTAAAGAACGCACAAGATTACGTACATTATTCCCTTACATCAATGAAGCAAG
TGAAAACCATAAAAAACGTGTTCAAAGTTCAACTTTAAATGAAGTTGTTACTGGTGCAATTTCCATGAACCCTACACCAA
CAGACAAAGGTAGACGTTTGAATGTCTTTTATGCAACACAAGTTGCTATAGAACCACCGACATTTGTTGTATTTGTTAAT
GATGTAGAATTAATGCATTTTTCTTATAAACGCTATTTAGAGAATCAAATCCGTGCCGCTTTTGGTTTTGAAGGTACACC
AATTCATATTATAGCTCGAAAGAGAAATTAA

Upstream 100 bases:

>100_bases
TTAAGTGCTGATTTTTATCATTACAGTAATAAACTCATTTTGAATACACAGTCTCATGTGATATTATTAAAAAGATATAA
GAAAGAGAGGAAGTTAGCTT

Downstream 100 bases:

>100_bases
CGATTGGGGGATAACAATGACTAAAATTACCGTTTTTGGTATGGGAAGTTTTGGGACAGCCCTTGCCAATGTTCTTGCAG
AAAATGGACATGATGTTTTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAI
DEAYVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVV
SHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFL
DYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTGAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVN
DVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN

Sequences:

>Translated_436_residues
MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAI
DEAYVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVV
SHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFL
DYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTGAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVN
DVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN
>Mature_435_residues
TKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAID
EAYVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVS
HFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYE
STEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLD
YAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTGAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVND
VELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=41.978021978022, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1788919, Length=179, Percent_Identity=34.0782122905028, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367268, Length=112, Percent_Identity=37.5, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=87, Percent_Identity=40.2298850574713, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=208, Percent_Identity=31.25, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45550813, Length=179, Percent_Identity=32.9608938547486, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48970; Mature: 48839

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGG
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHEECCCCEEEEECEEEECCC
IEIGDAPFQTQIRAQAEIAIDEAYVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNK
EEECCCCCHHHEEEEEEEEEECEEEEEEEEEHHCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSI
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
EECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCH
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVE
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHCCCHHHCEEECCCCEEEEEEECCCCCC
KDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLN
HHHHHHHHHHHHHHHHHHHCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVTGAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAA
HHHEEEEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCEEEEHHHHHHHHHHHHHHH
FGFEGTPIHIIARKRN
CCCCCCCEEEEEECCC
>Mature Secondary Structure 
TKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGG
CCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHEECCCCEEEEECEEEECCC
IEIGDAPFQTQIRAQAEIAIDEAYVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNK
EEECCCCCHHHEEEEEEEEEECEEEEEEEEEHHCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSI
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVY
EECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCH
ESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVE
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHCCCHHHCEEECCCCEEEEEEECCCCCC
KDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLN
HHHHHHHHHHHHHHHHHHHCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVTGAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAA
HHHEEEEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCEEEEHHHHHHHHHHHHHHH
FGFEGTPIHIIARKRN
CCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA