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The map label for this gene is oppB2

Identifier: 161509548

GI number: 161509548

Start: 1417911

End: 1418864

Strand: Reverse

Name: oppB2

Synonym: USA300HOU_1316

Alternate gene names: 161509548

Gene position: 1418864-1417911 (Counterclockwise)

Preceding gene: 161509549

Following gene: 161509547

Centisome position: 49.39

GC content: 31.45

Gene sequence:

>954_bases
ATGCAAATGATAGTTGTTTTATTTGTTATTTCTACACTTACATTCATTTTAATGAAATTATCACCAGGCAATCCTGTTGA
TAAAATATTACATCTTGATGTAGCACAAGTGTCGACGGAACAAATAAATGCAACCAAAGATAAATTGGGATTAAATGATT
CTTTATTGGTACAGTGGTGGCATTGGATGAATCATTTATTACATTTTAATTTAGGAAAAAGTTTTGAATCAAAAGAACCG
GTAACACAGATATTATTCAACTATGCACCCATAACATTACTCATATCATTTTCAACATTAGTAGTGTCGTTATGCATATC
TATACCGCTCGGCATTATAGCAGCCAAACGATTTCATAAGTGGACGGATAAAGTGATTAGAGTGATCTCAACACTATCGA
TTAGTTTACCAGCGTTCTTTATCGGTATTATTTTATTATTTATTGTCACAAATTTAATGAATATAGATAGCGTTATACTA
AGTCAGTTTATATTACCTGTAATCACGCTATCTTTAGGTATGTGTGCATACATCATTCGTTTAGTGCGTTCTAATTTATT
GATGTTATTGCAAAGTAATATCGTACAAGCATCAAGATTACGCGGTATGAATGAACGTTATATTTTAATTCATGATTTAC
TAAAACCAACAATTTTGCCGATTATCCCATTACTAGGGATTTCACTTGGCAGTCTAATAGGTGGTACTGTAGTGATTGAA
AATTTATTTGATATACCTGGTATTGGTTATCTATTAATGGATAGTATTAAATCTCGAGATTATCCTGTTATTCAAGGATG
CGTGTTATTTATTGGCTTCTTCGTTGTTATTATCAATACGATTGCTGATTTATTAACGTTATTACTTGATCCGAAGCAGC
GTTTACAATTAGGAAATCCAAAAATCAAAACCAATACACCATTGATATCAGAAAGTAGTGACCGTCATGCATAA

Upstream 100 bases:

>100_bases
GCATATACATGCGCCATTCTCATGTAAAAAGAAAGTGTTAGTAACTTACACAAGGAGGGGGACTATTATGTTCATAATAA
AGTCTATGTTGTATAGACTG

Downstream 100 bases:

>100_bases
AATATTTTCAAAGAATAACCTGATATTTTTTGTATTCGTTGCATTTATTTTTGTGGTAATTGTACTGCAATTCTTTGTCA
GTAGTGAAAATGCAACCAAA

Product: oligopeptide ABC transporter membrane protein

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQMIVVLFVISTLTFILMKLSPGNPVDKILHLDVAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEP
VTQILFNYAPITLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIVTNLMNIDSVIL
SQFILPVITLSLGMCAYIIRLVRSNLLMLLQSNIVQASRLRGMNERYILIHDLLKPTILPIIPLLGISLGSLIGGTVVIE
NLFDIPGIGYLLMDSIKSRDYPVIQGCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKIKTNTPLISESSDRHA

Sequences:

>Translated_317_residues
MQMIVVLFVISTLTFILMKLSPGNPVDKILHLDVAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEP
VTQILFNYAPITLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIVTNLMNIDSVIL
SQFILPVITLSLGMCAYIIRLVRSNLLMLLQSNIVQASRLRGMNERYILIHDLLKPTILPIIPLLGISLGSLIGGTVVIE
NLFDIPGIGYLLMDSIKSRDYPVIQGCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKIKTNTPLISESSDRHA
>Mature_317_residues
MQMIVVLFVISTLTFILMKLSPGNPVDKILHLDVAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEP
VTQILFNYAPITLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIVTNLMNIDSVIL
SQFILPVITLSLGMCAYIIRLVRSNLLMLLQSNIVQASRLRGMNERYILIHDLLKPTILPIIPLLGISLGSLIGGTVVIE
NLFDIPGIGYLLMDSIKSRDYPVIQGCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKIKTNTPLISESSDRHA

Specific function: Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S.aureus growth and survival during the infection process

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1789888, Length=300, Percent_Identity=33, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787053, Length=299, Percent_Identity=29.0969899665552, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787497, Length=302, Percent_Identity=27.1523178807947, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789965, Length=320, Percent_Identity=26.5625, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787761, Length=323, Percent_Identity=30.3405572755418, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=28.9377289377289, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788504, Length=354, Percent_Identity=23.4463276836158, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OPPB2_STAA3 (Q2FH55)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_493973.1
- ProteinModelPortal:   Q2FH55
- STRING:   Q2FH55
- EnsemblBacteria:   EBSTAT00000037252
- GeneID:   3914938
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1276
- eggNOG:   COG0601
- GeneTree:   EBGT00050000023945
- HOGENOM:   HBG724229
- OMA:   IREIANY
- ProtClustDB:   CLSK885311
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 35418; Mature: 35418

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1627c35c)-; HASH(0x166ee688)-; HASH(0x166dde74)-; HASH(0x166096a0)-; HASH(0x166ee658)-; HASH(0x15b3d3c8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCH
>Mature Secondary Structure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CCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA