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The map label for this gene is rnhC [H]

Identifier: 161509314

GI number: 161509314

Start: 1149585

End: 1150541

Strand: Reverse

Name: rnhC [H]

Synonym: USA300HOU_1075

Alternate gene names: 161509314

Gene position: 1150541-1149585 (Counterclockwise)

Preceding gene: 161509320

Following gene: 161509303

Centisome position: 40.05

GC content: 33.33

Gene sequence:

>957_bases
ATGAAAGGATTTACACAAATGGCGAATATCGTTTTTAAATTGTCGGATAAAGACATAACGACATTAATGTCACGCATTTC
TTTTGATACTGAGAATTTACCTCAAGGTATGAAAGCACGTGCAAAGTATCAAAATACAACTGTAAATATTTACCAATCAG
GTAAAGTCATGTTTCAAGGTAATCATGCAGAAGCTGTGTCTGAAGAACTTCTACCGCAGCATTCTCAATTGAATACTAAT
AAAACTAAAAAGAAAAATATGGCTAATTCTTTTCTTGAACAAACTTTAATGTATGATCAATTTAACTGTATTGGTAGTGA
TGAGGCTGGAAGTGGCGATTACTTTGGTCCGTTGACTGTGTGTGCTGCTTTCGTTACCAAAGAGCATGTCCCTATTTTAA
AAACTTTGGGTGTAGATGATTCAAAAAAATTAACCGATACCAAAATTGTAGAACTTGCTGAGCAATTGGTTACTTTCATA
CCACATTCATTATTAACACTACACAATGAAAAATATAATATTCAGCAAGCAAAAGGCTGGACTCAAGTAAAAATGAAAGC
TGCCCTTCATAATGAAGCCATCAAAAATGTACTTGAAAAAATTGATTCGTCTCAATTAGACTATATCGTCATTGATCAGT
TCGCAAAACGCGAAGTGTATAGCCATTACGCATTATCAGATATACCACTTCCAAAGAAAACAAAATTTGAAACAAAAGGA
GAATCGAAGTCATTAGCCATTGCAGTGGCAAGCATAATTTCTCGATACGCATTTGTTACATATATGGATCAAATATCAAA
AAATATTAATATGACGATTCCTAAAGGTGCCGGTGCTAAAGTCGATGTAATCGCCGCCAAAATTATAAAAAAATACGGTC
TTTCACGTTTAGATACCATTTCAAAAAAGCATTTTAAAAATCGTGAAAAAGCCCAAAAAATTTTAAAGCCTCTTTGA

Upstream 100 bases:

>100_bases
TTGTAAGTATCCGCAATTAATTCTTTACAACATACATAAATGTTTCTGACGTTATTATCATTTATGATATGATTATTTTT
GCTAAAGACAATGAAATTTT

Downstream 100 bases:

>100_bases
TTTTTAATCATTAGAGGCTTTTATGCAGTTGTGCGAAGCATCATCTGTATTCCGCTGTTCCTCTTTGACTTTTTAAATGC
ATTGGAACCAAATTGGTGAA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKGFTQMANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQGNHAEAVSEELLPQHSQLNTN
KTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVTFI
PHSLLTLHNEKYNIQQAKGWTQVKMKAALHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKG
ESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL

Sequences:

>Translated_318_residues
MKGFTQMANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQGNHAEAVSEELLPQHSQLNTN
KTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVTFI
PHSLLTLHNEKYNIQQAKGWTQVKMKAALHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKG
ESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL
>Mature_318_residues
MKGFTQMANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQGNHAEAVSEELLPQHSQLNTN
KTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVTFI
PHSLLTLHNEKYNIQQAKGWTQVKMKAALHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKG
ESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 35748; Mature: 35748

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFTQMANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQG
CCCHHHHHHHHHEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCEEEEEC
NHAEAVSEELLPQHSQLNTNKTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTV
CCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
CAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVTFIPHSLLTLHNEKYNIQQAKGW
HHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCH
TQVKMKAALHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCHHHHHH
SKKHFKNREKAQKILKPL
HHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MKGFTQMANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQG
CCCHHHHHHHHHEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCEEEEEC
NHAEAVSEELLPQHSQLNTNKTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTV
CCHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
CAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVTFIPHSLLTLHNEKYNIQQAKGW
HHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCH
TQVKMKAALHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCHHHHHH
SKKHFKNREKAQKILKPL
HHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA