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The map label for this gene is tldD [H]

Identifier: 160902624

GI number: 160902624

Start: 1247989

End: 1249401

Strand: Direct

Name: tldD [H]

Synonym: Pmob_1164

Alternate gene names: 160902624

Gene position: 1247989-1249401 (Clockwise)

Preceding gene: 160902623

Following gene: 160902625

Centisome position: 57.52

GC content: 38.08

Gene sequence:

>1413_bases
GTGAATTTAAGTAATGCTCAATACTTAGAGATTTTAAACCATTCTCTTTCATCGGGGGGAGAGTATTCAGAAATCTTCTA
TGAAGATTTTTATGGTACCTCGATTGTTTACGATAACGGTAAAATTGAAAAAATAAATTTTTCAAGTACAAAAGGTGCAA
GTATAAGGGTTGTATCAGCTGAAGAAACGATTTTTGCTCATACTAACGATCCCACATACGAGAATCTTATGAGTCTTGCT
GAGACTTTGAGAAAGAACGCAAGCGAAAGATTTGGCTCTAATGATATCGTAAAGGTTGAAGAATTGAAAGAGGCAGAAAA
GAGGGATTTTGCACCATTTGAAATACCTTTCGACAATGTACCTGTAGAACAAAAAGTAGAAAAGGTTCTTAAAGGTGTAG
AATTACTTAAGAATGCCGATAAACGCATCAAACAGATCACCGTTTCCTATGCAGATAGTAGTAGAAAGGTAAAAATAGTG
AATTCAGAAGGGAAAATAGTTGAGGATATTAGAAATTATCCACGTTATGCTGCTATAATATTTGCACAGGACGAAGAAGG
GAATTTGTTCAGAGGTTATTCCTCCGATGGAGCAAACATGGGATTTGAATTTTTTACAGATGAGATGATAGAAAAAGTAG
CAAAAGACGCCGTCAGACAAGTAGTTTCACAAATAGAAGGAGTGGATGCTCCTGCAGGCGAATTCACGGTTGTTTTGTCT
TCTGAAGCTGGAGGAACCATGATACATGAAGCATGTGGGCACGGTATGGAAGCAGACTTGGTACTTTCCGGTTCTGTGTA
CAGAGAAAAAGTTGGAAAGAAAATCGCTTCGGAAAAAATTACCGTTGTAGACGATGGAACAGATAAAAACAAAAGAGGGA
CCCTTAATTATGATGACGAGGGAACTCCTACCCAGAGGACCGTTTTAATTGAAAAAGGCGTGTTAAAAGGATACATGCAC
TCGAAAATAACTGCCAAAAAATTTGGTGTTGAACCCACAGGTAACGGTAGAAGGGAATCTTATATGGTGCTACCCATCGT
TAGGATGAGAAACACGATGATCTTACCAGGAGAAGATGATCCACAAGATATAATTAAATCTGTAAAATACGGTATATTTG
TTAGAAAGATGGGTGGAGGACAAGTTGATGTAATAAGTGGTGATTTTCAGTTTGGAGTTGATGAAGGTTATATTATAGAA
AATGGTGAAATAAAGCAATCGATCCGTGGAGCGAGCTTAGTTGGCAACGGATTAAAAGTCTTAGAAAGCATAGATATGGT
TGGTAATGATTTGGGATATGGTGTTGGAACCTGTGGTAAAGACGGTCAAGGGGCTCCAGTTTCCGATGCCCAGCCTACCA
TAAGAATACCGAAGTTAATTGTTGGTGGAATAGTAAAAGGGGGTAACAATTAA

Upstream 100 bases:

>100_bases
GTTACAATTATAATTACTGATACAAATACAAGTTCCAAGAGGAATAAATATGATATAATATGAAAGGAAGGATTGCTAAC
TTTTTATAGGAGGGATAGAA

Downstream 100 bases:

>100_bases
TGACTAATATAAAATCAATTATAGAAAAATCCATGAAAGAGATAAAAAGTAAAGGGCTTAAAGGACAGATAAATGTGATT
TCCACTGAAAGTAAGAATGC

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNLSNAQYLEILNHSLSSGGEYSEIFYEDFYGTSIVYDNGKIEKINFSSTKGASIRVVSAEETIFAHTNDPTYENLMSLA
ETLRKNASERFGSNDIVKVEELKEAEKRDFAPFEIPFDNVPVEQKVEKVLKGVELLKNADKRIKQITVSYADSSRKVKIV
NSEGKIVEDIRNYPRYAAIIFAQDEEGNLFRGYSSDGANMGFEFFTDEMIEKVAKDAVRQVVSQIEGVDAPAGEFTVVLS
SEAGGTMIHEACGHGMEADLVLSGSVYREKVGKKIASEKITVVDDGTDKNKRGTLNYDDEGTPTQRTVLIEKGVLKGYMH
SKITAKKFGVEPTGNGRRESYMVLPIVRMRNTMILPGEDDPQDIIKSVKYGIFVRKMGGGQVDVISGDFQFGVDEGYIIE
NGEIKQSIRGASLVGNGLKVLESIDMVGNDLGYGVGTCGKDGQGAPVSDAQPTIRIPKLIVGGIVKGGNN

Sequences:

>Translated_470_residues
MNLSNAQYLEILNHSLSSGGEYSEIFYEDFYGTSIVYDNGKIEKINFSSTKGASIRVVSAEETIFAHTNDPTYENLMSLA
ETLRKNASERFGSNDIVKVEELKEAEKRDFAPFEIPFDNVPVEQKVEKVLKGVELLKNADKRIKQITVSYADSSRKVKIV
NSEGKIVEDIRNYPRYAAIIFAQDEEGNLFRGYSSDGANMGFEFFTDEMIEKVAKDAVRQVVSQIEGVDAPAGEFTVVLS
SEAGGTMIHEACGHGMEADLVLSGSVYREKVGKKIASEKITVVDDGTDKNKRGTLNYDDEGTPTQRTVLIEKGVLKGYMH
SKITAKKFGVEPTGNGRRESYMVLPIVRMRNTMILPGEDDPQDIIKSVKYGIFVRKMGGGQVDVISGDFQFGVDEGYIIE
NGEIKQSIRGASLVGNGLKVLESIDMVGNDLGYGVGTCGKDGQGAPVSDAQPTIRIPKLIVGGIVKGGNN
>Mature_470_residues
MNLSNAQYLEILNHSLSSGGEYSEIFYEDFYGTSIVYDNGKIEKINFSSTKGASIRVVSAEETIFAHTNDPTYENLMSLA
ETLRKNASERFGSNDIVKVEELKEAEKRDFAPFEIPFDNVPVEQKVEKVLKGVELLKNADKRIKQITVSYADSSRKVKIV
NSEGKIVEDIRNYPRYAAIIFAQDEEGNLFRGYSSDGANMGFEFFTDEMIEKVAKDAVRQVVSQIEGVDAPAGEFTVVLS
SEAGGTMIHEACGHGMEADLVLSGSVYREKVGKKIASEKITVVDDGTDKNKRGTLNYDDEGTPTQRTVLIEKGVLKGYMH
SKITAKKFGVEPTGNGRRESYMVLPIVRMRNTMILPGEDDPQDIIKSVKYGIFVRKMGGGQVDVISGDFQFGVDEGYIIE
NGEIKQSIRGASLVGNGLKVLESIDMVGNDLGYGVGTCGKDGQGAPVSDAQPTIRIPKLIVGGIVKGGNN

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=451, Percent_Identity=38.8026607538803, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1790682, Length=420, Percent_Identity=23.0952380952381, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51431; Mature: 51431

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSNAQYLEILNHSLSSGGEYSEIFYEDFYGTSIVYDNGKIEKINFSSTKGASIRVVSA
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCEEEEEEC
EETIFAHTNDPTYENLMSLAETLRKNASERFGSNDIVKVEELKEAEKRDFAPFEIPFDNV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCEECCCCCC
PVEQKVEKVLKGVELLKNADKRIKQITVSYADSSRKVKIVNSEGKIVEDIRNYPRYAAII
CHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCCHHHHHHHCCCCEEEEE
FAQDEEGNLFRGYSSDGANMGFEFFTDEMIEKVAKDAVRQVVSQIEGVDAPAGEFTVVLS
EEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
SEAGGTMIHEACGHGMEADLVLSGSVYREKVGKKIASEKITVVDDGTDKNKRGTLNYDDE
CCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCC
GTPTQRTVLIEKGVLKGYMHSKITAKKFGVEPTGNGRRESYMVLPIVRMRNTMILPGEDD
CCCCCEEEEEEHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEEEEEHHCCEEEECCCCC
PQDIIKSVKYGIFVRKMGGGQVDVISGDFQFGVDEGYIIENGEIKQSIRGASLVGNGLKV
HHHHHHHHHHCEEEEECCCCEEEEEECCEEECCCCCEEEECCCHHHHHCCHHHHCCHHHH
LESIDMVGNDLGYGVGTCGKDGQGAPVSDAQPTIRIPKLIVGGIVKGGNN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHCCCEECCCCC
>Mature Secondary Structure
MNLSNAQYLEILNHSLSSGGEYSEIFYEDFYGTSIVYDNGKIEKINFSSTKGASIRVVSA
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCEEEEEEC
EETIFAHTNDPTYENLMSLAETLRKNASERFGSNDIVKVEELKEAEKRDFAPFEIPFDNV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCEECCCCCC
PVEQKVEKVLKGVELLKNADKRIKQITVSYADSSRKVKIVNSEGKIVEDIRNYPRYAAII
CHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCCHHHHHHHCCCCEEEEE
FAQDEEGNLFRGYSSDGANMGFEFFTDEMIEKVAKDAVRQVVSQIEGVDAPAGEFTVVLS
EEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
SEAGGTMIHEACGHGMEADLVLSGSVYREKVGKKIASEKITVVDDGTDKNKRGTLNYDDE
CCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCC
GTPTQRTVLIEKGVLKGYMHSKITAKKFGVEPTGNGRRESYMVLPIVRMRNTMILPGEDD
CCCCCEEEEEEHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEEEEEHHCCEEEECCCCC
PQDIIKSVKYGIFVRKMGGGQVDVISGDFQFGVDEGYIIENGEIKQSIRGASLVGNGLKV
HHHHHHHHHHCEEEEECCCCEEEEEECCEEECCCCCEEEECCCHHHHHCCHHHHCCHHHH
LESIDMVGNDLGYGVGTCGKDGQGAPVSDAQPTIRIPKLIVGGIVKGGNN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]