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The map label for this gene is fusA [C]

Identifier: 160902344

GI number: 160902344

Start: 934743

End: 936815

Strand: Direct

Name: fusA [C]

Synonym: Pmob_0879

Alternate gene names: 160902344

Gene position: 934743-936815 (Clockwise)

Preceding gene: 160902343

Following gene: 160902345

Centisome position: 43.08

GC content: 35.75

Gene sequence:

>2073_bases
GTGAGTGAATATAACGCTGAAAAAAAGAGGATCATAGGATTCTTTGGACATCATGGATGTGGCAAAACTACCCTTATGGA
CGATGTCCTTGTAAATCTTGGATTAACTGATAGAATAGGTCAAAGACATTTAGACAAGGATCCTGTTGAAAAAGAAAAAG
GAGCAACCTTTTCTAACCACATTTTCTCGTTCGATTTAGATGATTCAAGAATGTACTTTTTTGATACACCGGGATCTTTA
GACTTTATAGGAGATATACAAATAGCTTTAAACGCTGTGGACAACGTAGTTATTGTAATAAACGCTTCTGCTGGTGTAGA
AGTGACAACAGAAAGAATTTGGAATATGGCGAGAGAATTAAACAAGCCTATCGTATTTTATGTAAACCAAATGGATAAAG
AAGAAGTTAACTTCGGAAACTTAATGCAAGAACTCAAAGAAAGTTTTGAGGAAGAAATAAGAATAGTTCCTTTCCAGGTT
CCCATAGGTGAAGGCTCAGATTTTAAAGGAGTTATAAATCTTTTATCAAATGACGTATTTATATATGAAGAAGGGACAGG
CAAATCCTCCAAACAGAGTGAAATCCCTGATAATGCTAAAGATTATTTGGAAAGATTTCATTCTGAAATAATAGAAGATA
TTGTTGAAACCAACGAAGAACTAATGGAAAAATATTTTGAATCCGGCGAAGAAGGATTAAGTCAAGAAGAATTGATTTCC
TCACTTCATAAAGCGTATGATGAAGATAAAATAATTCCTGTATTCATTGGATCTGCTTTAAAAAACATTGGTTTTGATCA
ATTGATAAAGGCTTTAATGAGTTTCGGAATGACCCCCCTTGAAAGAAAGTTTCACACTGAAGAAGGCACTGAGATTTTTT
CCCAAGAAGATGGTCAGTTTTTAGGTATCATCGTTAAAAATGAAGTAGACCCGTTCGTTGGAAAACTCACCTATCTAAGG
GTTATTAGCGGTTCTTTAAAAGCCGGTTCTAGTATCTATATTGTTGAAGAATCCACAAGAGAAAAGATTTCCCATATCAA
CATACCTAGATTTGATAAGAACGAAGAAGTCGAAGTCGCTGGTGTTGGCGATATCTTAGTTATACCTAAGCTAAAATCGA
GTAAAATAAATCAAACCGTATCCAGTGAAGAAACGTCAAATAGGCTGAAATTACCAGAATTTCCAGAACCGATGATATCT
AAGTCTATCGCCCCTAATTCTAAAAATGAAATAGACAAAATTACTGAATCGTTGGCAAAAATTGCAGAGTCAGACCCAAC
ATTTAAATGGGAATTCGATGCGGAAACTGGAGAAACGGTCATAAGTGGAATGGGAACCATTCACTTAGAAATAATGATAG
AGAAATTGAAGAAGAATTTCGGCATTGATTTTGAGGTAGGAAAACCAAAAATTGCTTACAAAGAAACCATAAGAAGCAAA
ACACAGGCGGAGTACAAACACAAGAAACAAACTGGAGGTCATGGTCAATACGGTCACGTTAAAATAGAAATTGAACCGCT
AGAAAGAGGAAAAGGCTATGAATTTGTTGATAAAATCGTTGGAGGAGTCATCCCAAAAAATTTCATACCATCCGTAGACA
AAGGTATCAGAGAAGCTATCAAAAAAGGTGTTTTGGCTGGTTTTCCTGTTGTTGATATTAGGGTCACTCTTTTTGATGGC
TCTTACCATGAAGTTGACTCTTCAGATATTTCATTTCAAATAGCTGCAAGGCACGCATTTAAAATAGCTATGGAAAGCGA
CACCCCGGTTATTTTAGAACCAATTATGCATGTTGAAATATTCTTACCCACTGAAAACACAGGAGATGTTATCGGTGAAG
TTACAGCTAAAAGGGGAAGGCCTTTAGGAATGGAATCAGCCGGGAAAGGATACGATAAGATAGTGGCTGAAATTCCATTG
GCTGAAATGCTGGATTTTTCACCTCGTCTCAGTTCTATCTCCTCAGGAAAGGGTTATTTTACCATGAAATTTTCCCATTA
TTCAGAAGTCAGCCCTGATATACAAAACAAAATAATAGAAGAAAGAAGAAGGGAAGAAGAATTACAAAAATAA

Upstream 100 bases:

>100_bases
ATTTCAAAAACGAAAAAACTCGTAATTATATTCCCGTGCTTCTAAGTGTTTATAAAAAAATCCCGTAGTTAAGAAATAGA
TTTAGAATGGAGGGGTAATA

Downstream 100 bases:

>100_bases
AATGGGGCTATGCCCCATTTTTATATATCTTTTGCAGCTTTGTGCAAAATGGTTTTTTAAGTTTGCCGCATTGTGCAAAC
TGTGGCACTTCAAAACTAAG

Product: small GTP-binding protein

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MSEYNAEKKRIIGFFGHHGCGKTTLMDDVLVNLGLTDRIGQRHLDKDPVEKEKGATFSNHIFSFDLDDSRMYFFDTPGSL
DFIGDIQIALNAVDNVVIVINASAGVEVTTERIWNMARELNKPIVFYVNQMDKEEVNFGNLMQELKESFEEEIRIVPFQV
PIGEGSDFKGVINLLSNDVFIYEEGTGKSSKQSEIPDNAKDYLERFHSEIIEDIVETNEELMEKYFESGEEGLSQEELIS
SLHKAYDEDKIIPVFIGSALKNIGFDQLIKALMSFGMTPLERKFHTEEGTEIFSQEDGQFLGIIVKNEVDPFVGKLTYLR
VISGSLKAGSSIYIVEESTREKISHINIPRFDKNEEVEVAGVGDILVIPKLKSSKINQTVSSEETSNRLKLPEFPEPMIS
KSIAPNSKNEIDKITESLAKIAESDPTFKWEFDAETGETVISGMGTIHLEIMIEKLKKNFGIDFEVGKPKIAYKETIRSK
TQAEYKHKKQTGGHGQYGHVKIEIEPLERGKGYEFVDKIVGGVIPKNFIPSVDKGIREAIKKGVLAGFPVVDIRVTLFDG
SYHEVDSSDISFQIAARHAFKIAMESDTPVILEPIMHVEIFLPTENTGDVIGEVTAKRGRPLGMESAGKGYDKIVAEIPL
AEMLDFSPRLSSISSGKGYFTMKFSHYSEVSPDIQNKIIEERRREEELQK

Sequences:

>Translated_690_residues
MSEYNAEKKRIIGFFGHHGCGKTTLMDDVLVNLGLTDRIGQRHLDKDPVEKEKGATFSNHIFSFDLDDSRMYFFDTPGSL
DFIGDIQIALNAVDNVVIVINASAGVEVTTERIWNMARELNKPIVFYVNQMDKEEVNFGNLMQELKESFEEEIRIVPFQV
PIGEGSDFKGVINLLSNDVFIYEEGTGKSSKQSEIPDNAKDYLERFHSEIIEDIVETNEELMEKYFESGEEGLSQEELIS
SLHKAYDEDKIIPVFIGSALKNIGFDQLIKALMSFGMTPLERKFHTEEGTEIFSQEDGQFLGIIVKNEVDPFVGKLTYLR
VISGSLKAGSSIYIVEESTREKISHINIPRFDKNEEVEVAGVGDILVIPKLKSSKINQTVSSEETSNRLKLPEFPEPMIS
KSIAPNSKNEIDKITESLAKIAESDPTFKWEFDAETGETVISGMGTIHLEIMIEKLKKNFGIDFEVGKPKIAYKETIRSK
TQAEYKHKKQTGGHGQYGHVKIEIEPLERGKGYEFVDKIVGGVIPKNFIPSVDKGIREAIKKGVLAGFPVVDIRVTLFDG
SYHEVDSSDISFQIAARHAFKIAMESDTPVILEPIMHVEIFLPTENTGDVIGEVTAKRGRPLGMESAGKGYDKIVAEIPL
AEMLDFSPRLSSISSGKGYFTMKFSHYSEVSPDIQNKIIEERRREEELQK
>Mature_689_residues
SEYNAEKKRIIGFFGHHGCGKTTLMDDVLVNLGLTDRIGQRHLDKDPVEKEKGATFSNHIFSFDLDDSRMYFFDTPGSLD
FIGDIQIALNAVDNVVIVINASAGVEVTTERIWNMARELNKPIVFYVNQMDKEEVNFGNLMQELKESFEEEIRIVPFQVP
IGEGSDFKGVINLLSNDVFIYEEGTGKSSKQSEIPDNAKDYLERFHSEIIEDIVETNEELMEKYFESGEEGLSQEELISS
LHKAYDEDKIIPVFIGSALKNIGFDQLIKALMSFGMTPLERKFHTEEGTEIFSQEDGQFLGIIVKNEVDPFVGKLTYLRV
ISGSLKAGSSIYIVEESTREKISHINIPRFDKNEEVEVAGVGDILVIPKLKSSKINQTVSSEETSNRLKLPEFPEPMISK
SIAPNSKNEIDKITESLAKIAESDPTFKWEFDAETGETVISGMGTIHLEIMIEKLKKNFGIDFEVGKPKIAYKETIRSKT
QAEYKHKKQTGGHGQYGHVKIEIEPLERGKGYEFVDKIVGGVIPKNFIPSVDKGIREAIKKGVLAGFPVVDIRVTLFDGS
YHEVDSSDISFQIAARHAFKIAMESDTPVILEPIMHVEIFLPTENTGDVIGEVTAKRGRPLGMESAGKGYDKIVAEIPLA
EMLDFSPRLSSISSGKGYFTMKFSHYSEVSPDIQNKIIEERRREEELQK

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=702, Percent_Identity=32.9059829059829, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI19923640, Length=719, Percent_Identity=25.8692628650904, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI25306287, Length=719, Percent_Identity=24.7566063977747, Blast_Score=236, Evalue=6e-62,
Organism=Homo sapiens, GI25306283, Length=388, Percent_Identity=27.0618556701031, Blast_Score=150, Evalue=6e-36,
Organism=Escherichia coli, GI1789738, Length=699, Percent_Identity=36.1945636623748, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1790835, Length=509, Percent_Identity=23.7721021611002, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17533571, Length=699, Percent_Identity=28.755364806867, Blast_Score=332, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI17556745, Length=721, Percent_Identity=23.4396671289875, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17557151, Length=150, Percent_Identity=28.6666666666667, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323098, Length=706, Percent_Identity=30.8781869688385, Blast_Score=335, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6322359, Length=787, Percent_Identity=23.2528589580686, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324707, Length=345, Percent_Identity=22.3188405797101, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320593, Length=345, Percent_Identity=22.3188405797101, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582462, Length=708, Percent_Identity=30.9322033898305, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI221458488, Length=720, Percent_Identity=26.25, Blast_Score=226, Evalue=6e-59,
Organism=Drosophila melanogaster, GI78706572, Length=149, Percent_Identity=31.5436241610738, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 77519; Mature: 77388

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYNAEKKRIIGFFGHHGCGKTTLMDDVLVNLGLTDRIGQRHLDKDPVEKEKGATFSNH
CCCCCCCHHHEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHCCCCCHHC
IFSFDLDDSRMYFFDTPGSLDFIGDIQIALNAVDNVVIVINASAGVEVTTERIWNMAREL
EEEEECCCCEEEEEECCCCCEEEEHHHHEEECCCCEEEEEECCCCCEEHHHHHHHHHHHH
NKPIVFYVNQMDKEEVNFGNLMQELKESFEEEIRIVPFQVPIGEGSDFKGVINLLSNDVF
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEECCCCCCHHHHHHHHCCCEE
IYEEGTGKSSKQSEIPDNAKDYLERFHSEIIEDIVETNEELMEKYFESGEEGLSQEELIS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHCCCCHHHHHH
SLHKAYDEDKIIPVFIGSALKNIGFDQLIKALMSFGMTPLERKFHTEEGTEIFSQEDGQF
HHHHHCCCCCEEHEEHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCCCCE
LGIIVKNEVDPFVGKLTYLRVISGSLKAGSSIYIVEESTREKISHINIPRFDKNEEVEVA
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCEEEE
GVGDILVIPKLKSSKINQTVSSEETSNRLKLPEFPEPMISKSIAPNSKNEIDKITESLAK
ECCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
IAESDPTFKWEFDAETGETVISGMGTIHLEIMIEKLKKNFGIDFEVGKPKIAYKETIRSK
HHCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
TQAEYKHKKQTGGHGQYGHVKIEIEPLERGKGYEFVDKIVGGVIPKNFIPSVDKGIREAI
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
KKGVLAGFPVVDIRVTLFDGSYHEVDSSDISFQIAARHAFKIAMESDTPVILEPIMHVEI
HCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEEEEECCCCCEEEECCEEEEE
FLPTENTGDVIGEVTAKRGRPLGMESAGKGYDKIVAEIPLAEMLDFSPRLSSISSGKGYF
EEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCHHCCCCCCCEE
TMKFSHYSEVSPDIQNKIIEERRREEELQK
EEEECCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEYNAEKKRIIGFFGHHGCGKTTLMDDVLVNLGLTDRIGQRHLDKDPVEKEKGATFSNH
CCCCCCHHHEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHCCCCCHHC
IFSFDLDDSRMYFFDTPGSLDFIGDIQIALNAVDNVVIVINASAGVEVTTERIWNMAREL
EEEEECCCCEEEEEECCCCCEEEEHHHHEEECCCCEEEEEECCCCCEEHHHHHHHHHHHH
NKPIVFYVNQMDKEEVNFGNLMQELKESFEEEIRIVPFQVPIGEGSDFKGVINLLSNDVF
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEECCCCCCHHHHHHHHCCCEE
IYEEGTGKSSKQSEIPDNAKDYLERFHSEIIEDIVETNEELMEKYFESGEEGLSQEELIS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHCCCCHHHHHH
SLHKAYDEDKIIPVFIGSALKNIGFDQLIKALMSFGMTPLERKFHTEEGTEIFSQEDGQF
HHHHHCCCCCEEHEEHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHCCCCCCE
LGIIVKNEVDPFVGKLTYLRVISGSLKAGSSIYIVEESTREKISHINIPRFDKNEEVEVA
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCEEEE
GVGDILVIPKLKSSKINQTVSSEETSNRLKLPEFPEPMISKSIAPNSKNEIDKITESLAK
ECCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
IAESDPTFKWEFDAETGETVISGMGTIHLEIMIEKLKKNFGIDFEVGKPKIAYKETIRSK
HHCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
TQAEYKHKKQTGGHGQYGHVKIEIEPLERGKGYEFVDKIVGGVIPKNFIPSVDKGIREAI
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
KKGVLAGFPVVDIRVTLFDGSYHEVDSSDISFQIAARHAFKIAMESDTPVILEPIMHVEI
HCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEEEEECCCCCEEEECCEEEEE
FLPTENTGDVIGEVTAKRGRPLGMESAGKGYDKIVAEIPLAEMLDFSPRLSSISSGKGYF
EEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCHHCCCCCCCEE
TMKFSHYSEVSPDIQNKIIEERRREEELQK
EEEECCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]