Click here to switch to the map view.

The map label for this gene is rsmH

Identifier: 160902330

GI number: 160902330

Start: 918635

End: 919495

Strand: Direct

Name: rsmH

Synonym: Pmob_0865

Alternate gene names: 160902330

Gene position: 918635-919495 (Clockwise)

Preceding gene: 160902329

Following gene: 160902331

Centisome position: 42.34

GC content: 34.15

Gene sequence:

>861_bases
ATGGTTGAGGAAGTCTTATCCTATATGATAACCAACAAAGACGGCATTTATGTGGATTGTACCGCAGGCGAAGGTGGACA
TATAAAAGCTATTTTAGGATACACCAACAATAAAGCTAAGGTAATCGGTGTAGATGTTGACTACGAAGTATTGGAAATCG
CAGAAGAAAGGTTAAAGGATTTATCGGATAACGTGGTATTGATTAAATCATCTTATAAAAATATAGATATGGTTTTGAGA
GGCTTAGGTATTGACAAAGTTGACGGTTTTTTAATGGATTTAGGAGTTTCTACCTTTCAGTTAAAAGGTGAAAATAGGGG
ATTTTCTTTTACTAAAGACGAACCTTTAGATATGAGAATGGATGTTCAATCGGAAAAAGATGCAGCATACATAGTCAACA
ATTATTCACAAGAAGACCTTAGGCGTATCATTTTTGAATATGGAGAAGAAAAAAGGTTTGCTCACAGCATTTCAAAAAGC
ATTGTAAAAAACAGACCTATAAATACTACACAAGAGTTAGTAGACGCCATTAGAAAAGGGTTACCTGCTTCGCAAGTTCA
CGAAAGGCACAGACATTTTGCCACCAAAACTTTCCAAGCCCTCAGAATAGAAGTTAATGAAGAATTAAAAAACATCGAAG
AAACCCTTTCTAAATTTGAAAGCTTTTTAAAGGTAAAGGCAAGGGTAGCTGTAATAACTTTTCATTCTCTGGAAGACAGG
ATCGTTAAAAATTTTTTCAAAAATAATGAAAGATATAATTTTCTTACTCCCAAACCTATTTTACCTACGCAAGAAGAAAT
AAAACACAATCCAAGAAGTAGAAGTGCAAAATTGAGAGTGGTTGAGTATTTAGGGGCTTAA

Upstream 100 bases:

>100_bases
GTTATTCTTTGCGAAATATAAGTAAAAAAATTAATTTGTTTTTCTGCAAAAGAGGTGTATAATAATAGTAAGAAAATACG
ACGATTTTCATAAAAGTGTA

Downstream 100 bases:

>100_bases
AGAATGATAAGAGTTAGGGGGAGTTTTTATGGAAAGAAATGTGTACGCAAAAAGCAAAGCGATAGAAAAGACTAAATCTA
AAGTCAAATCTCTCGATATT

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MVEEVLSYMITNKDGIYVDCTAGEGGHIKAILGYTNNKAKVIGVDVDYEVLEIAEERLKDLSDNVVLIKSSYKNIDMVLR
GLGIDKVDGFLMDLGVSTFQLKGENRGFSFTKDEPLDMRMDVQSEKDAAYIVNNYSQEDLRRIIFEYGEEKRFAHSISKS
IVKNRPINTTQELVDAIRKGLPASQVHERHRHFATKTFQALRIEVNEELKNIEETLSKFESFLKVKARVAVITFHSLEDR
IVKNFFKNNERYNFLTPKPILPTQEEIKHNPRSRSAKLRVVEYLGA

Sequences:

>Translated_286_residues
MVEEVLSYMITNKDGIYVDCTAGEGGHIKAILGYTNNKAKVIGVDVDYEVLEIAEERLKDLSDNVVLIKSSYKNIDMVLR
GLGIDKVDGFLMDLGVSTFQLKGENRGFSFTKDEPLDMRMDVQSEKDAAYIVNNYSQEDLRRIIFEYGEEKRFAHSISKS
IVKNRPINTTQELVDAIRKGLPASQVHERHRHFATKTFQALRIEVNEELKNIEETLSKFESFLKVKARVAVITFHSLEDR
IVKNFFKNNERYNFLTPKPILPTQEEIKHNPRSRSAKLRVVEYLGA
>Mature_286_residues
MVEEVLSYMITNKDGIYVDCTAGEGGHIKAILGYTNNKAKVIGVDVDYEVLEIAEERLKDLSDNVVLIKSSYKNIDMVLR
GLGIDKVDGFLMDLGVSTFQLKGENRGFSFTKDEPLDMRMDVQSEKDAAYIVNNYSQEDLRRIIFEYGEEKRFAHSISKS
IVKNRPINTTQELVDAIRKGLPASQVHERHRHFATKTFQALRIEVNEELKNIEETLSKFESFLKVKARVAVITFHSLEDR
IVKNFFKNNERYNFLTPKPILPTQEEIKHNPRSRSAKLRVVEYLGA

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=331, Percent_Identity=35.3474320241692, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI165377202, Length=185, Percent_Identity=36.7567567567568, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786270, Length=312, Percent_Identity=35.5769230769231, Blast_Score=182, Evalue=3e-47,
Organism=Drosophila melanogaster, GI62472493, Length=328, Percent_Identity=32.0121951219512, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571637, Length=328, Percent_Identity=32.0121951219512, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_PETMO (A9BHH9)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001567911.1
- ProteinModelPortal:   A9BHH9
- SMR:   A9BHH9
- GeneID:   5757125
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_0865
- HOGENOM:   HBG302779
- OMA:   RPINSTL
- BioCyc:   PMOB403833:PMOB_0865-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 32837; Mature: 32837

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: BINDING 45-45 BINDING 79-79 BINDING 93-93 BINDING 100-100

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEEVLSYMITNKDGIYVDCTAGEGGHIKAILGYTNNKAKVIGVDVDYEVLEIAEERLKD
CHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHC
LSDNVVLIKSSYKNIDMVLRGLGIDKVDGFLMDLGVSTFQLKGENRGFSFTKDEPLDMRM
CCCCEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEE
DVQSEKDAAYIVNNYSQEDLRRIIFEYGEEKRFAHSISKSIVKNRPINTTQELVDAIRKG
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LPASQVHERHRHFATKTFQALRIEVNEELKNIEETLSKFESFLKVKARVAVITFHSLEDR
CCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHH
IVKNFFKNNERYNFLTPKPILPTQEEIKHNPRSRSAKLRVVEYLGA
HHHHHHHCCCCEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MVEEVLSYMITNKDGIYVDCTAGEGGHIKAILGYTNNKAKVIGVDVDYEVLEIAEERLKD
CHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHC
LSDNVVLIKSSYKNIDMVLRGLGIDKVDGFLMDLGVSTFQLKGENRGFSFTKDEPLDMRM
CCCCEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEE
DVQSEKDAAYIVNNYSQEDLRRIIFEYGEEKRFAHSISKSIVKNRPINTTQELVDAIRKG
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LPASQVHERHRHFATKTFQALRIEVNEELKNIEETLSKFESFLKVKARVAVITFHSLEDR
CCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHH
IVKNFFKNNERYNFLTPKPILPTQEEIKHNPRSRSAKLRVVEYLGA
HHHHHHHCCCCEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA