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The map label for this gene is infC [H]

Identifier: 160902176

GI number: 160902176

Start: 759825

End: 760352

Strand: Direct

Name: infC [H]

Synonym: Pmob_0709

Alternate gene names: 160902176

Gene position: 759825-760352 (Clockwise)

Preceding gene: 160902175

Following gene: 160902177

Centisome position: 35.02

GC content: 33.14

Gene sequence:

>528_bases
TTGTGTATAAGCGATAAAGTCGCTAAAAATAATGAGATCAAAGCTAGAAAAGTTCTGGTAATAGATCAAGAGGGGAACAA
ACTCGGAGAGATGCCGACAAAAGAAGCGTTAAAATTAGCCGAACAATCAGGAGTGGATTTGGTTTTAGTAGCCCCTGAAG
CTAAACCTCCAGTTGCCAGAATGATGGATTATGGTAAATATATCTACGAAAAAGAGAAAAAGGAAAAATTAGCTAAGAAA
AAGCAAAAAAAACAAGTTCTTAAAGAGATGAAATTTAGACTCAGAATCGATGATCATGATTTCAACACCAAATTGAAAAA
GATAAGGGAATTTTTAGAAGATGGCTATAAAGTAAGAGCAGTAATTATGTTCTTAGGTAGAGATATACTTTTTAAAGAAA
AAGGTAAGGAAATACTTGACAAAGTGGTATCTCAAACGTCGGATATAGCAAAAGTTTCCAGAGGGGCAAAATTATTGGGT
AAAGATATGGATATTATTTTAGAGCCAATCAATGAGGAGAAAAAATAA

Upstream 100 bases:

>100_bases
AAAAATGACTCTTTGGTTAGGAAAAGAGAGTTATTTGTGTTTAAGAAGAAATGGGTGACGATCCGTCACCCATTTTTTAT
ATGTTAAATAAGGAAGGTGA

Downstream 100 bases:

>100_bases
GTAATCTACATATACTCTAAAAATTGGGAGGAATCAAGATGCCTAAATTAAAGACAAAAGGTTCTGCGAAAAAAAGGTTC
AAGGTCACAAAAAACGGAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MCISDKVAKNNEIKARKVLVIDQEGNKLGEMPTKEALKLAEQSGVDLVLVAPEAKPPVARMMDYGKYIYEKEKKEKLAKK
KQKKQVLKEMKFRLRIDDHDFNTKLKKIREFLEDGYKVRAVIMFLGRDILFKEKGKEILDKVVSQTSDIAKVSRGAKLLG
KDMDIILEPINEEKK

Sequences:

>Translated_175_residues
MCISDKVAKNNEIKARKVLVIDQEGNKLGEMPTKEALKLAEQSGVDLVLVAPEAKPPVARMMDYGKYIYEKEKKEKLAKK
KQKKQVLKEMKFRLRIDDHDFNTKLKKIREFLEDGYKVRAVIMFLGRDILFKEKGKEILDKVVSQTSDIAKVSRGAKLLG
KDMDIILEPINEEKK
>Mature_175_residues
MCISDKVAKNNEIKARKVLVIDQEGNKLGEMPTKEALKLAEQSGVDLVLVAPEAKPPVARMMDYGKYIYEKEKKEKLAKK
KQKKQVLKEMKFRLRIDDHDFNTKLKKIREFLEDGYKVRAVIMFLGRDILFKEKGKEILDKVVSQTSDIAKVSRGAKLLG
KDMDIILEPINEEKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=161, Percent_Identity=42.8571428571429, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20150; Mature: 20150

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCISDKVAKNNEIKARKVLVIDQEGNKLGEMPTKEALKLAEQSGVDLVLVAPEAKPPVAR
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHH
MMDYGKYIYEKEKKEKLAKKKQKKQVLKEMKFRLRIDDHDFNTKLKKIREFLEDGYKVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCHHHHH
VIMFLGRDILFKEKGKEILDKVVSQTSDIAKVSRGAKLLGKDMDIILEPINEEKK
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MCISDKVAKNNEIKARKVLVIDQEGNKLGEMPTKEALKLAEQSGVDLVLVAPEAKPPVAR
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHH
MMDYGKYIYEKEKKEKLAKKKQKKQVLKEMKFRLRIDDHDFNTKLKKIREFLEDGYKVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCHHHHH
VIMFLGRDILFKEKGKEILDKVVSQTSDIAKVSRGAKLLGKDMDIILEPINEEKK
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]