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The map label for this gene is ogg [H]

Identifier: 160902174

GI number: 160902174

Start: 758512

End: 759168

Strand: Direct

Name: ogg [H]

Synonym: Pmob_0707

Alternate gene names: 160902174

Gene position: 758512-759168 (Clockwise)

Preceding gene: 160902173

Following gene: 160902175

Centisome position: 34.96

GC content: 32.88

Gene sequence:

>657_bases
ATGATCCATTCTAACATAACAAATTCTTTAGATATTTTGGTCAATAAAATAGAAGATGTGAAACTTACAATTAAGGATGA
AGTTGAAAGAAGGTTTGAAGAGTTTAAGGATATTGGAAAAAATGGCGATGAATTGGACTTATTCAGTGAACTATCTTTTT
GTGTATTAACGGCAAATTGGAGGGCAAAGGGTGGCATAAAAGCTCAGAAATTTATCACAAAAGAGGGATTCGCTCACTAT
AACGAAGAGCAATTAATATCAAAATTAAGAGAAGTTGGACATAGATTCCCAAATACCAGATCACGATATATAGTCGAAAA
TAGATGGATAATTGGAAGTTTGAAAAACTTACTTCAAAAAGATATTTCAGAAAGCAGAAGGTTTTTAGTCGAAAATATAA
AAGGTATAGGCTGGAAAGAAGCCAGCCATTTTTTAAGAAACGTTGGAATAGAAGACGTCGCTATATTAGATAAGCACATA
CTGAAAATCATGAAGAATTATAATCTCGTGAAAGAAGTCCCCAAACCTTCTTGGACGGAGAAAAAGTATACTGATCTGGA
AAATCAACTGAGAGTTTTATCAAAGATGGTTGAAGAACCATTAGGGAAATTAGATCTTTATCTATGGTACATGGAAACGG
GCCAAATTGACAAATAA

Upstream 100 bases:

>100_bases
TCTTTATTTCTCTTATAATTTATATGATCTTAGGTTTTTTCTTAATTGTAAGATCCAACAGAAAAAAAGGTAATAATTGA
CACAATCTTGGAGGAATAAG

Downstream 100 bases:

>100_bases
AAAAACTATTAACATATATAACATATTAAATTTCACATAAATTTGATAGCCTACATTATGGTTATTTGTGATTTTTTATC
AAAAAATACAAAAGGGGGAA

Product: N-glycosylase/DNA lyase

Products: NA

Alternate protein names: 8-oxoguanine DNA glycosylase; DNA-(apurinic or apyrimidinic site) lyase; AP lyase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIHSNITNSLDILVNKIEDVKLTIKDEVERRFEEFKDIGKNGDELDLFSELSFCVLTANWRAKGGIKAQKFITKEGFAHY
NEEQLISKLREVGHRFPNTRSRYIVENRWIIGSLKNLLQKDISESRRFLVENIKGIGWKEASHFLRNVGIEDVAILDKHI
LKIMKNYNLVKEVPKPSWTEKKYTDLENQLRVLSKMVEEPLGKLDLYLWYMETGQIDK

Sequences:

>Translated_218_residues
MIHSNITNSLDILVNKIEDVKLTIKDEVERRFEEFKDIGKNGDELDLFSELSFCVLTANWRAKGGIKAQKFITKEGFAHY
NEEQLISKLREVGHRFPNTRSRYIVENRWIIGSLKNLLQKDISESRRFLVENIKGIGWKEASHFLRNVGIEDVAILDKHI
LKIMKNYNLVKEVPKPSWTEKKYTDLENQLRVLSKMVEEPLGKLDLYLWYMETGQIDK
>Mature_218_residues
MIHSNITNSLDILVNKIEDVKLTIKDEVERRFEEFKDIGKNGDELDLFSELSFCVLTANWRAKGGIKAQKFITKEGFAHY
NEEQLISKLREVGHRFPNTRSRYIVENRWIIGSLKNLLQKDISESRRFLVENIKGIGWKEASHFLRNVGIEDVAILDKHI
LKIMKNYNLVKEVPKPSWTEKKYTDLENQLRVLSKMVEEPLGKLDLYLWYMETGQIDK

Specific function: Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) [H]

COG id: COG1059

COG function: function code L; Thermostable 8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-2 OGG1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012092
- InterPro:   IPR011257
- InterPro:   IPR003265 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =4.2.99.18 [H]

Molecular weight: Translated: 25598; Mature: 25598

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHSNITNSLDILVNKIEDVKLTIKDEVERRFEEFKDIGKNGDELDLFSELSFCVLTANW
CCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCC
RAKGGIKAQKFITKEGFAHYNEEQLISKLREVGHRFPNTRSRYIVENRWIIGSLKNLLQK
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHH
DISESRRFLVENIKGIGWKEASHFLRNVGIEDVAILDKHILKIMKNYNLVKEVPKPSWTE
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
KKYTDLENQLRVLSKMVEEPLGKLDLYLWYMETGQIDK
HHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCC
>Mature Secondary Structure
MIHSNITNSLDILVNKIEDVKLTIKDEVERRFEEFKDIGKNGDELDLFSELSFCVLTANW
CCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCC
RAKGGIKAQKFITKEGFAHYNEEQLISKLREVGHRFPNTRSRYIVENRWIIGSLKNLLQK
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHH
DISESRRFLVENIKGIGWKEASHFLRNVGIEDVAILDKHILKIMKNYNLVKEVPKPSWTE
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
KKYTDLENQLRVLSKMVEEPLGKLDLYLWYMETGQIDK
HHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]