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The map label for this gene is plsC [H]

Identifier: 160901674

GI number: 160901674

Start: 185430

End: 186206

Strand: Direct

Name: plsC [H]

Synonym: Pmob_0186

Alternate gene names: 160901674

Gene position: 185430-186206 (Clockwise)

Preceding gene: 160901656

Following gene: 160901675

Centisome position: 8.55

GC content: 31.66

Gene sequence:

>777_bases
ATGAAAAAGGTATTAGAAACAATAAAGGCAATATTCTTCACAATATGGTTAATTATCGGATTTCTCGGAGTTGTAATTGT
ATATGGAAGTTATGTGTTGATAAAAGCCAATATCTTGGAAAAAAGAAAGGGACACAAAGTCTCTCAAGAATATATTAGAA
AGGTTGTATCTTGGTTTGGAAAAGTTACTTTTAAATTCTTAAATAGTAAGATTTCAGTTCATGGTGAAGAGAATATTCCT
CAGCAAGGCCCTTATGTAGTAGTAGCGAATCATCAAAGCCTTTTCGATATTCCTTTAATTTTAGGATATATATATCCCAC
AGCTTTTATTGCAAAAAAAGAGCTTTCTATGATTCCTATATTAGGAAATTTCATCAAAAGACTTGGCTCTATCTTCATAG
ATAGGAATAATTCAAAAAGTGGTGCTATAGCTCTTAAAAAATTTGCAAAAATATCTCAATCAGGGGAAATTATAACTATT
TTTCCTGAAGGAACAAGGAGTTTAGATGGTCAAGTAGGTGAATTTAAAAAGGGAGCTCTTTTAATCCCTTTTAGATATAA
TATAAAACTATTACCTGTCACAATAGATGGAACTATCAAAATGAGCAAAAAAGGAAGCGTCTTTATCAAACCTTCGAATG
TTAATCTATTCATACATGAACCAGTCGAGCCAAAACTTTTCGCTAGCGAAGGAGAATTAAGAGAATGTCTCAAAAGCATA
ATCAGCGAAAATATTACAAGCGAACCTCAACTAGCTTTAAAAGAAACAAGAGCGTAA

Upstream 100 bases:

>100_bases
AAAAGTATAAGATTGAAGATAGTAAAGTCTCATAAATTGATCACTTTGAATCATAGTCTCATGTATCTTAAAGAAAAGGG
AAGAAAAAGGAGGACAATTC

Downstream 100 bases:

>100_bases
TTTCAGTTTTTTAAAGGAGGTTTTCAAACATGAAAAAAGTAAGCAATGTTACTATGGGAATAGATAAAGTTTCAAATTCA
CCGATAGTTTTTTTAAAGGT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKKVLETIKAIFFTIWLIIGFLGVVIVYGSYVLIKANILEKRKGHKVSQEYIRKVVSWFGKVTFKFLNSKISVHGEENIP
QQGPYVVVANHQSLFDIPLILGYIYPTAFIAKKELSMIPILGNFIKRLGSIFIDRNNSKSGAIALKKFAKISQSGEIITI
FPEGTRSLDGQVGEFKKGALLIPFRYNIKLLPVTIDGTIKMSKKGSVFIKPSNVNLFIHEPVEPKLFASEGELRECLKSI
ISENITSEPQLALKETRA

Sequences:

>Translated_258_residues
MKKVLETIKAIFFTIWLIIGFLGVVIVYGSYVLIKANILEKRKGHKVSQEYIRKVVSWFGKVTFKFLNSKISVHGEENIP
QQGPYVVVANHQSLFDIPLILGYIYPTAFIAKKELSMIPILGNFIKRLGSIFIDRNNSKSGAIALKKFAKISQSGEIITI
FPEGTRSLDGQVGEFKKGALLIPFRYNIKLLPVTIDGTIKMSKKGSVFIKPSNVNLFIHEPVEPKLFASEGELRECLKSI
ISENITSEPQLALKETRA
>Mature_258_residues
MKKVLETIKAIFFTIWLIIGFLGVVIVYGSYVLIKANILEKRKGHKVSQEYIRKVVSWFGKVTFKFLNSKISVHGEENIP
QQGPYVVVANHQSLFDIPLILGYIYPTAFIAKKELSMIPILGNFIKRLGSIFIDRNNSKSGAIALKKFAKISQSGEIITI
FPEGTRSLDGQVGEFKKGALLIPFRYNIKLLPVTIDGTIKMSKKGSVFIKPSNVNLFIHEPVEPKLFASEGELRECLKSI
ISENITSEPQLALKETRA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=131, Percent_Identity=30.5343511450382, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15100175, Length=131, Percent_Identity=30.5343511450382, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=150, Percent_Identity=34, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=196, Percent_Identity=32.6530612244898, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364648, Length=179, Percent_Identity=28.4916201117318, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582856, Length=179, Percent_Identity=28.4916201117318, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582854, Length=179, Percent_Identity=28.4916201117318, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28929; Mature: 28929

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLETIKAIFFTIWLIIGFLGVVIVYGSYVLIKANILEKRKGHKVSQEYIRKVVSWFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHH
KVTFKFLNSKISVHGEENIPQQGPYVVVANHQSLFDIPLILGYIYPTAFIAKKELSMIPI
HHHHHHHCCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LGNFIKRLGSIFIDRNNSKSGAIALKKFAKISQSGEIITIFPEGTRSLDGQVGEFKKGAL
HHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEE
LIPFRYNIKLLPVTIDGTIKMSKKGSVFIKPSNVNLFIHEPVEPKLFASEGELRECLKSI
EEEEEECEEEEEEEECCEEEECCCCCEEEEECCEEEEEECCCCCCEECCCCHHHHHHHHH
ISENITSEPQLALKETRA
HHCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MKKVLETIKAIFFTIWLIIGFLGVVIVYGSYVLIKANILEKRKGHKVSQEYIRKVVSWFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHCCCCHHHHHHHHHHHHHH
KVTFKFLNSKISVHGEENIPQQGPYVVVANHQSLFDIPLILGYIYPTAFIAKKELSMIPI
HHHHHHHCCEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
LGNFIKRLGSIFIDRNNSKSGAIALKKFAKISQSGEIITIFPEGTRSLDGQVGEFKKGAL
HHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEE
LIPFRYNIKLLPVTIDGTIKMSKKGSVFIKPSNVNLFIHEPVEPKLFASEGELRECLKSI
EEEEEECEEEEEEEECCEEEECCCCCEEEEECCEEEEEECCCCCCEECCCCHHHHHHHHH
ISENITSEPQLALKETRA
HHCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]