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The map label for this gene is mnaA [H]

Identifier: 160901613

GI number: 160901613

Start: 123297

End: 124400

Strand: Direct

Name: mnaA [H]

Synonym: Pmob_0123

Alternate gene names: 160901613

Gene position: 123297-124400 (Clockwise)

Preceding gene: 160901610

Following gene: 160901616

Centisome position: 5.68

GC content: 35.51

Gene sequence:

>1104_bases
ATGAAAATAGCGATGATATTTGGAACACGGCCAGAAGCAATAAAAATGGCACCATTATACAAAAAGCTGAAAGAAGAAAA
TATGGAGGTAAAAGTAATAGCAACCGCTCAGCACAGAGAAATGCTCGATCAAGTGTTGAATCTTTTCGAAATAAAACCAG
ACTACGACTTAAATATAATGACAAAAAATCAAACTCTACCACAACTAACTTCAAAACTAGTTACAGAGATAGATAAAATA
CTAAAAATTGAACCATTCGATTACATACTAGTACAAGGGGATACAACCTCCACTTTTGTTGGAAGTCTCGCTGCTTTTTA
CAACAAAATATTTGTTGGGCACGTGGAAGCGGGTTTAAGAACGAACGACATATACAACCCCTTCCCAGAAGAAATGAACA
GAAGACTAACAGGTACAATTGCAAAGCATCACTTTGCTTCTACCCAAAAGGCAAAAGATAACCTACTAAAAGAAGGTGTA
GAAGAAAAAAACATAATAGTAACAGGGAACACGGTTATAGATGCATTACTATGGGTAAAAGAAAATAAAAACAAAGATAT
AGAAAAGATAAAAGAAAAGTACAACATAAAGAACAAAAAGTTTATCTTAGTAACCATGCATAGAAGGGAGAACTGGGGAA
AACCGATAGAAAACGTGATGAAAGCGATAAAAAGGTATCTACACGAAAACGAAGAAATGCATATAGTATTTCCAGTTCAC
TTAAATCCGATAGTGAGAGAAAGTGTGTATAAAATACTTGGGAATGAGGAAAAAGCGATATTGATAGATCCTGTTGAATA
CTTAGAATTCATCGCGTTAATGGACGAAAGTCATTACATAATGACAGATTCAGGAGGGATACAAGAAGAAGCACCCACAT
TGGGCAAACCAACGTTGGTATTAAGAGAAACAACGGAAAGGCCTGAAGCAATAGAAGCGGGAACAGCAAAATTAATAGGA
ACACAAGAAGAACAAGTGTATCAAGCCATGAAAGAACTAGAAACAGAAAAATATGCTCAAATGAGCAAAGCGAGCAACCC
TTTTGGGGATGGCAAGGCATCTCAAAGAATCGTTGAATTTTTGAAAAAAAGATATTACTCTTGA

Upstream 100 bases:

>100_bases
AAGGGGAACCCCCTTAACGTTCGGCGAAGGGGCGCTAACAAAGACTAAACGCAGCTTACATAAAAAAACTAAAAACATTA
CCATAACAAGGAGTCCTCGA

Downstream 100 bases:

>100_bases
TAAGGGCTATTTTCACTTGCCACCATTCTATTCCCTGACAACTCAGATCTATAATACAGTTCGTCGTAGAGTTGTAAAAA
ATCTTTAATAGAAGTCTCTT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKIAMIFGTRPEAIKMAPLYKKLKEENMEVKVIATAQHREMLDQVLNLFEIKPDYDLNIMTKNQTLPQLTSKLVTEIDKI
LKIEPFDYILVQGDTTSTFVGSLAAFYNKIFVGHVEAGLRTNDIYNPFPEEMNRRLTGTIAKHHFASTQKAKDNLLKEGV
EEKNIIVTGNTVIDALLWVKENKNKDIEKIKEKYNIKNKKFILVTMHRRENWGKPIENVMKAIKRYLHENEEMHIVFPVH
LNPIVRESVYKILGNEEKAILIDPVEYLEFIALMDESHYIMTDSGGIQEEAPTLGKPTLVLRETTERPEAIEAGTAKLIG
TQEEQVYQAMKELETEKYAQMSKASNPFGDGKASQRIVEFLKKRYYS

Sequences:

>Translated_367_residues
MKIAMIFGTRPEAIKMAPLYKKLKEENMEVKVIATAQHREMLDQVLNLFEIKPDYDLNIMTKNQTLPQLTSKLVTEIDKI
LKIEPFDYILVQGDTTSTFVGSLAAFYNKIFVGHVEAGLRTNDIYNPFPEEMNRRLTGTIAKHHFASTQKAKDNLLKEGV
EEKNIIVTGNTVIDALLWVKENKNKDIEKIKEKYNIKNKKFILVTMHRRENWGKPIENVMKAIKRYLHENEEMHIVFPVH
LNPIVRESVYKILGNEEKAILIDPVEYLEFIALMDESHYIMTDSGGIQEEAPTLGKPTLVLRETTERPEAIEAGTAKLIG
TQEEQVYQAMKELETEKYAQMSKASNPFGDGKASQRIVEFLKKRYYS
>Mature_367_residues
MKIAMIFGTRPEAIKMAPLYKKLKEENMEVKVIATAQHREMLDQVLNLFEIKPDYDLNIMTKNQTLPQLTSKLVTEIDKI
LKIEPFDYILVQGDTTSTFVGSLAAFYNKIFVGHVEAGLRTNDIYNPFPEEMNRRLTGTIAKHHFASTQKAKDNLLKEGV
EEKNIIVTGNTVIDALLWVKENKNKDIEKIKEKYNIKNKKFILVTMHRRENWGKPIENVMKAIKRYLHENEEMHIVFPVH
LNPIVRESVYKILGNEEKAILIDPVEYLEFIALMDESHYIMTDSGGIQEEAPTLGKPTLVLRETTERPEAIEAGTAKLIG
TQEEQVYQAMKELETEKYAQMSKASNPFGDGKASQRIVEFLKKRYYS

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=375, Percent_Identity=52.2666666666667, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42268; Mature: 42268

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAMIFGTRPEAIKMAPLYKKLKEENMEVKVIATAQHREMLDQVLNLFEIKPDYDLNIM
CEEEEEECCCCCCEEHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCEEEE
TKNQTLPQLTSKLVTEIDKILKIEPFDYILVQGDTTSTFVGSLAAFYNKIFVGHVEAGLR
ECCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHHHHHHHHHEEHHCCCC
TNDIYNPFPEEMNRRLTGTIAKHHFASTQKAKDNLLKEGVEEKNIIVTGNTVIDALLWVK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHH
ENKNKDIEKIKEKYNIKNKKFILVTMHRRENWGKPIENVMKAIKRYLHENEEMHIVFPVH
CCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEC
LNPIVRESVYKILGNEEKAILIDPVEYLEFIALMDESHYIMTDSGGIQEEAPTLGKPTLV
CCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEE
LRETTERPEAIEAGTAKLIGTQEEQVYQAMKELETEKYAQMSKASNPFGDGKASQRIVEF
EECCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LKKRYYS
HHHHCCC
>Mature Secondary Structure
MKIAMIFGTRPEAIKMAPLYKKLKEENMEVKVIATAQHREMLDQVLNLFEIKPDYDLNIM
CEEEEEECCCCCCEEHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCEEEE
TKNQTLPQLTSKLVTEIDKILKIEPFDYILVQGDTTSTFVGSLAAFYNKIFVGHVEAGLR
ECCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHHHHHHHHHEEHHCCCC
TNDIYNPFPEEMNRRLTGTIAKHHFASTQKAKDNLLKEGVEEKNIIVTGNTVIDALLWVK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHH
ENKNKDIEKIKEKYNIKNKKFILVTMHRRENWGKPIENVMKAIKRYLHENEEMHIVFPVH
CCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEC
LNPIVRESVYKILGNEEKAILIDPVEYLEFIALMDESHYIMTDSGGIQEEAPTLGKPTLV
CCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEE
LRETTERPEAIEAGTAKLIGTQEEQVYQAMKELETEKYAQMSKASNPFGDGKASQRIVEF
EECCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LKKRYYS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]