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The map label for this gene is argF [H]

Identifier: 160901559

GI number: 160901559

Start: 63400

End: 64389

Strand: Direct

Name: argF [H]

Synonym: Pmob_0068

Alternate gene names: 160901559

Gene position: 63400-64389 (Clockwise)

Preceding gene: 160901558

Following gene: 160901560

Centisome position: 2.92

GC content: 35.25

Gene sequence:

>990_bases
ATGCCTATCAATTTAAGAGGAAGAAGCCTTTTAACGTTGAAAGATTTCACACCAGAAGAGATAAAGTATCTTTTGGAGCT
TTCAAAAGATCTAAAAGCCAAAAAGCGAATGGGTATTAAGGGGGATTTGTTAAAGGGTAAGAACATAGTTTTGCTATTTG
AAAAAACATCAACAAGAACAAGATGCGCCTTTGAAGTAGCTGCTTTCGATGAAGGGGCAAACGTTACATTTCTAACTAAC
AGTCAAATGGGAAAGAAAGAGTCAATAGAAGATACGGCAAGAGTTTTAGGAAGATTTTACGATGGTATAGAATTTAGAGG
CTTCAAGCAAGAAACGGTAGAAATTTTAGCAAAATATTCAGGTGTTCCCGTGTGGAATGGTTTAACAGATGAAGATCATC
CCACCCAAGTTTTGGCAGATTTCTTAACTATTATGGAAAATTTTGAAAAACCTCTTAATAAGATCAAGTTTGTGTACGTT
GGTGATGGAAGAAACAATATGGCAAACGCCCTCATGATTGGTGCCTCTAAAATGGGTATGGATTTTGTAATTATTTCTCC
AAAAGAACTTTTCCCAAGTAAAGAACTGATAAGTGAAATGGAAACGACAGCTAACGAAAACGGTGGAAAAATTACCATCA
CAGACAAACTTGATGCCGTTGCTAATGCAGATGTAATTTATACTGATGTCTGGATTTCTATGGGAGAAGAAAGTAAAGTT
GAAGAGAGGATCAAATTACTTAAACCTTACCAAGTAAATATGGATTTGATAAAAAAGACAAACAATCCTGAAGTTATTTT
CCTTCATTGTTTGCCTTCTTTTCACGACACAAAAACCGATATGGGATACGATATTTATCAGAAATACGGCCTTACAGAAA
TGGAAGTTACGGATGAAGTGTTTCAAAGTAAGTACTCAAAAGTTTTTGATGAAGCAGAAAATAGAATGCATACCATAAAA
GCAGTTATGGTAGCAACGTTGGTAGGTTGA

Upstream 100 bases:

>100_bases
AAAAACATCATTTTTTCCAAGGTAAGGGGTCACCATTCAGGGTAGACCCTGAAAAACTCAAAAAAGTCTTAGAAGGATAA
AAAGGAGGAATTAAAGAAGC

Downstream 100 bases:

>100_bases
TAGGAATGGCTGAAAAACTTGCAATTGTAGCAATAGGAGGAAATGCCTTATCCCAACCAAAAGAATCTCCAACCGCTGAA
AATATGCTAAAAAACTTAGA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPINLRGRSLLTLKDFTPEEIKYLLELSKDLKAKKRMGIKGDLLKGKNIVLLFEKTSTRTRCAFEVAAFDEGANVTFLTN
SQMGKKESIEDTARVLGRFYDGIEFRGFKQETVEILAKYSGVPVWNGLTDEDHPTQVLADFLTIMENFEKPLNKIKFVYV
GDGRNNMANALMIGASKMGMDFVIISPKELFPSKELISEMETTANENGGKITITDKLDAVANADVIYTDVWISMGEESKV
EERIKLLKPYQVNMDLIKKTNNPEVIFLHCLPSFHDTKTDMGYDIYQKYGLTEMEVTDEVFQSKYSKVFDEAENRMHTIK
AVMVATLVG

Sequences:

>Translated_329_residues
MPINLRGRSLLTLKDFTPEEIKYLLELSKDLKAKKRMGIKGDLLKGKNIVLLFEKTSTRTRCAFEVAAFDEGANVTFLTN
SQMGKKESIEDTARVLGRFYDGIEFRGFKQETVEILAKYSGVPVWNGLTDEDHPTQVLADFLTIMENFEKPLNKIKFVYV
GDGRNNMANALMIGASKMGMDFVIISPKELFPSKELISEMETTANENGGKITITDKLDAVANADVIYTDVWISMGEESKV
EERIKLLKPYQVNMDLIKKTNNPEVIFLHCLPSFHDTKTDMGYDIYQKYGLTEMEVTDEVFQSKYSKVFDEAENRMHTIK
AVMVATLVG
>Mature_328_residues
PINLRGRSLLTLKDFTPEEIKYLLELSKDLKAKKRMGIKGDLLKGKNIVLLFEKTSTRTRCAFEVAAFDEGANVTFLTNS
QMGKKESIEDTARVLGRFYDGIEFRGFKQETVEILAKYSGVPVWNGLTDEDHPTQVLADFLTIMENFEKPLNKIKFVYVG
DGRNNMANALMIGASKMGMDFVIISPKELFPSKELISEMETTANENGGKITITDKLDAVANADVIYTDVWISMGEESKVE
ERIKLLKPYQVNMDLIKKTNNPEVIFLHCLPSFHDTKTDMGYDIYQKYGLTEMEVTDEVFQSKYSKVFDEAENRMHTIKA
VMVATLVG

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=330, Percent_Identity=41.5151515151515, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI18105007, Length=332, Percent_Identity=23.4939759036145, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=56.441717791411, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1786469, Length=330, Percent_Identity=55.4545454545455, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI2367364, Length=234, Percent_Identity=29.0598290598291, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=327, Percent_Identity=33.9449541284404, Blast_Score=171, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6322331, Length=297, Percent_Identity=29.96632996633, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24642586, Length=166, Percent_Identity=31.9277108433735, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37283; Mature: 37151

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPINLRGRSLLTLKDFTPEEIKYLLELSKDLKAKKRMGIKGDLLKGKNIVLLFEKTSTRT
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCC
RCAFEVAAFDEGANVTFLTNSQMGKKESIEDTARVLGRFYDGIEFRGFKQETVEILAKYS
EEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
GVPVWNGLTDEDHPTQVLADFLTIMENFEKPLNKIKFVYVGDGRNNMANALMIGASKMGM
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEECHHCCC
DFVIISPKELFPSKELISEMETTANENGGKITITDKLDAVANADVIYTDVWISMGEESKV
EEEEECCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCEEEEEEEEECCCCHHH
EERIKLLKPYQVNMDLIKKTNNPEVIFLHCLPSFHDTKTDMGYDIYQKYGLTEMEVTDEV
HHHHHHCCCEECCHHHEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
FQSKYSKVFDEAENRMHTIKAVMVATLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PINLRGRSLLTLKDFTPEEIKYLLELSKDLKAKKRMGIKGDLLKGKNIVLLFEKTSTRT
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCC
RCAFEVAAFDEGANVTFLTNSQMGKKESIEDTARVLGRFYDGIEFRGFKQETVEILAKYS
EEEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
GVPVWNGLTDEDHPTQVLADFLTIMENFEKPLNKIKFVYVGDGRNNMANALMIGASKMGM
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEECHHCCC
DFVIISPKELFPSKELISEMETTANENGGKITITDKLDAVANADVIYTDVWISMGEESKV
EEEEECCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCEEEEEEEEECCCCHHH
EERIKLLKPYQVNMDLIKKTNNPEVIFLHCLPSFHDTKTDMGYDIYQKYGLTEMEVTDEV
HHHHHHCCCEECCHHHEECCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
FQSKYSKVFDEAENRMHTIKAVMVATLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA