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The map label for this gene is waaA [H]

Identifier: 160877579

GI number: 160877579

Start: 5289830

End: 5291092

Strand: Reverse

Name: waaA [H]

Synonym: Sbal195_4478

Alternate gene names: 160877579

Gene position: 5291092-5289830 (Counterclockwise)

Preceding gene: 160877585

Following gene: 160877577

Centisome position: 98.95

GC content: 49.72

Gene sequence:

>1263_bases
ATGAATCGTTTTCTCTATTCCACGATCTTATATTTATTATCCCCTTTGCTAATCGTCTATTTAGCATTTCGTGCTATCAA
AAGTCCCGATTACCGTGGTCGTTGGGGGGAGCGTTTTGGATTAACCCAACTAAAATCGACGGATTTACTGATCCATTCTG
TGTCTATGGGGGAAACGCTCGCGGCAATCCCTTTGATCCGTTTGATTATGCAATCACACCCTGAGCTAAGTATTACGGTT
ACCACAACCAGTCCAACAGGATCTGCGCAGGTGCGCAAAGCCTTTGGTGACTCAGTGCAACATTGTTATTTGCCCTTTGA
CTTACCTTGGTGCGTGCGGCGTTTCTTGCGCCAAGTCTCACCTAAATCTTGCATCATTATGGAAACCGAACTGTGGCCTA
ACTTAGTTGCTGTTGCTGCTAAACGCGGTGTGCGCTTGATGTTAGCGAATGCTCGCTTATCGGCCAAGTCGGCGGCGCAA
TATGCTAAGCGCCCTAAACTCAGTCGACCTATGTTGCAACGACTCGATGTTATTGCGGTGCAGACTCAAGTAGAAGCGCA
ACGTTTTATCGAGTTAGGAGTATCGCCGGACAGAGTGACAGTATGCGGTAGCTTGAAATTTGATCTCAGTATTACGCCTG
AGCGTTTAGCTAATGCCAAGCAGTTGCGTCAGGCTTGGGGACGTGAAACCTCGCCGATTTGGGTTGCTGGCAGTGTGCAT
CCTGGAGAATTTGACGCCATGCTCGCCGCCCATAGGCAATTATTGGCTCTGTGGCCCGATGCCTTGATGATTATTGCACC
GCGTCATCCTGAGCAGTTTTCTGCCGTTGCTGAGGTTGTTGCCAGCCAAGGTTTTGAATTAATTCGTCGCAGCAGTAATC
TTCCTCTGACGGCAACGACTCAAGTGCTGGTCGGCGATACCATGGGTGAACTTCTGACTTTTTACGGCGCGGCGGACCAA
GCTTTTGTCGGTGGTACGCTGATCAATAATGGTGGCCATAATCCCTTGGAGCCAGTCGCTATGGGCGTGCCTGTTATGGT
GGGGCCGAACCATTGGGACTTTGCCCAAATTACCCTGATGTTGGCGGATGCTGGTGGGTTAAGGATTGTCGCTTCGTCGG
ATGAACTGGCGGCTAACTTGATTGCCTATTTTGCTAAACCTGAGTTGCGCCAGCTGGCAGCAAACGCGGGATTGGCAGTG
GTTGAGGCAAATCGCGGTGCCTTGCAACGACAATTTCTTCTCGCGCAATCATTAATCAATTAA

Upstream 100 bases:

>100_bases
TTAACCAACGACCGCCATACTGCTGGTAAATTATCCCTAATTTGGTGCATATGCTAACATTGCCGCCATTCAACAGGCAA
AACTCATAAGCACGTTTTTA

Downstream 100 bases:

>100_bases
TTCAACAAGATAATTTATTTAGTGGTTCAGGCGCTTTGCATCGCCGCTTGGTAGCCCAGCAGTAGTGATGACCAGTTATC
GGCAGTGAAGGCAAGGTTTG

Product: 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNRFLYSTILYLLSPLLIVYLAFRAIKSPDYRGRWGERFGLTQLKSTDLLIHSVSMGETLAAIPLIRLIMQSHPELSITV
TTTSPTGSAQVRKAFGDSVQHCYLPFDLPWCVRRFLRQVSPKSCIIMETELWPNLVAVAAKRGVRLMLANARLSAKSAAQ
YAKRPKLSRPMLQRLDVIAVQTQVEAQRFIELGVSPDRVTVCGSLKFDLSITPERLANAKQLRQAWGRETSPIWVAGSVH
PGEFDAMLAAHRQLLALWPDALMIIAPRHPEQFSAVAEVVASQGFELIRRSSNLPLTATTQVLVGDTMGELLTFYGAADQ
AFVGGTLINNGGHNPLEPVAMGVPVMVGPNHWDFAQITLMLADAGGLRIVASSDELAANLIAYFAKPELRQLAANAGLAV
VEANRGALQRQFLLAQSLIN

Sequences:

>Translated_420_residues
MNRFLYSTILYLLSPLLIVYLAFRAIKSPDYRGRWGERFGLTQLKSTDLLIHSVSMGETLAAIPLIRLIMQSHPELSITV
TTTSPTGSAQVRKAFGDSVQHCYLPFDLPWCVRRFLRQVSPKSCIIMETELWPNLVAVAAKRGVRLMLANARLSAKSAAQ
YAKRPKLSRPMLQRLDVIAVQTQVEAQRFIELGVSPDRVTVCGSLKFDLSITPERLANAKQLRQAWGRETSPIWVAGSVH
PGEFDAMLAAHRQLLALWPDALMIIAPRHPEQFSAVAEVVASQGFELIRRSSNLPLTATTQVLVGDTMGELLTFYGAADQ
AFVGGTLINNGGHNPLEPVAMGVPVMVGPNHWDFAQITLMLADAGGLRIVASSDELAANLIAYFAKPELRQLAANAGLAV
VEANRGALQRQFLLAQSLIN
>Mature_420_residues
MNRFLYSTILYLLSPLLIVYLAFRAIKSPDYRGRWGERFGLTQLKSTDLLIHSVSMGETLAAIPLIRLIMQSHPELSITV
TTTSPTGSAQVRKAFGDSVQHCYLPFDLPWCVRRFLRQVSPKSCIIMETELWPNLVAVAAKRGVRLMLANARLSAKSAAQ
YAKRPKLSRPMLQRLDVIAVQTQVEAQRFIELGVSPDRVTVCGSLKFDLSITPERLANAKQLRQAWGRETSPIWVAGSVH
PGEFDAMLAAHRQLLALWPDALMIIAPRHPEQFSAVAEVVASQGFELIRRSSNLPLTATTQVLVGDTMGELLTFYGAADQ
AFVGGTLINNGGHNPLEPVAMGVPVMVGPNHWDFAQITLMLADAGGLRIVASSDELAANLIAYFAKPELRQLAANAGLAV
VEANRGALQRQFLLAQSLIN

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=412, Percent_Identity=48.0582524271845, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 46072; Mature: 46072

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFLYSTILYLLSPLLIVYLAFRAIKSPDYRGRWGERFGLTQLKSTDLLIHSVSMGETL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHH
AAIPLIRLIMQSHPELSITVTTTSPTGSAQVRKAFGDSVQHCYLPFDLPWCVRRFLRQVS
HHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
PKSCIIMETELWPNLVAVAAKRGVRLMLANARLSAKSAAQYAKRPKLSRPMLQRLDVIAV
CCCEEEEEHHHCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
QTQVEAQRFIELGVSPDRVTVCGSLKFDLSITPERLANAKQLRQAWGRETSPIWVAGSVH
HHHHHHHHHHHCCCCCCCEEEEEEEEEEEEECHHHHHCHHHHHHHHCCCCCCEEEEECCC
PGEFDAMLAAHRQLLALWPDALMIIAPRHPEQFSAVAEVVASQGFELIRRSSNLPLTATT
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHCCCCCCEEEEE
QVLVGDTMGELLTFYGAADQAFVGGTLINNGGHNPLEPVAMGVPVMVGPNHWDFAQITLM
HEEECCHHHHHHHHHCCCCCCEECCEEEECCCCCCCCHHHCCCCEEECCCCCCCEEEEEE
LADAGGLRIVASSDELAANLIAYFAKPELRQLAANAGLAVVEANRGALQRQFLLAQSLIN
EECCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRFLYSTILYLLSPLLIVYLAFRAIKSPDYRGRWGERFGLTQLKSTDLLIHSVSMGETL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHH
AAIPLIRLIMQSHPELSITVTTTSPTGSAQVRKAFGDSVQHCYLPFDLPWCVRRFLRQVS
HHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
PKSCIIMETELWPNLVAVAAKRGVRLMLANARLSAKSAAQYAKRPKLSRPMLQRLDVIAV
CCCEEEEEHHHCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
QTQVEAQRFIELGVSPDRVTVCGSLKFDLSITPERLANAKQLRQAWGRETSPIWVAGSVH
HHHHHHHHHHHCCCCCCCEEEEEEEEEEEEECHHHHHCHHHHHHHHCCCCCCEEEEECCC
PGEFDAMLAAHRQLLALWPDALMIIAPRHPEQFSAVAEVVASQGFELIRRSSNLPLTATT
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHCCCCCCEEEEE
QVLVGDTMGELLTFYGAADQAFVGGTLINNGGHNPLEPVAMGVPVMVGPNHWDFAQITLM
HEEECCHHHHHHHHHCCCCCCEECCEEEECCCCCCCCHHHCCCCEEECCCCCCCEEEEEE
LADAGGLRIVASSDELAANLIAYFAKPELRQLAANAGLAVVEANRGALQRQFLLAQSLIN
EECCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]