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The map label for this gene is dsbD [H]

Identifier: 160877459

GI number: 160877459

Start: 5149954

End: 5152065

Strand: Reverse

Name: dsbD [H]

Synonym: Sbal195_4357

Alternate gene names: 160877459

Gene position: 5152065-5149954 (Counterclockwise)

Preceding gene: 160877460

Following gene: 160877458

Centisome position: 96.35

GC content: 49.86

Gene sequence:

>2112_bases
ATGAGTACATTAAAATCCATGTTAACCAGATTCTGGATACTCGCCTTGATAGTGACGAGTCCGTCACTATTGGCCGCATC
GACGGGGTGGTTAGTTAACGATAATCACCCGCCAGCCAAAGTACGTTTTATGCTGACGGGCGAAGTTGATCCCACAACGA
ATACTTTGCCCGCTGTGCTTGAAGTACAACTTGAGGGTGATTGGAAAACCTATTGGCGTAGCCCTGGGGAAGGCGGTATC
GCGCCTACCATCAAATGGGATGGCTCACACAATCTACAGCAAGTAGATTGGAGGTGGCCAGCGCCAGAGGAATTCTCATT
ATTGGGATTACAAACCTTTGGTTACAAAGGAAATACCACCTTCCCATTAACCCTAAAAGTCGATGATATCGCTGCACCAA
CCCAGCTGCGCGGCAAAGTGACCTTGTCGACCTGTACCACTATCTGTGTACTGACGGATTATCAGATTAGTCTCGACTTC
ACGCCCAATGCGCTGCAAGCAGATACCGATGCCATGTTGGCCTACAACAAGGCCGTGTCGCTTGTGCCACAAAAAGTGTT
GTCCCAAGAGGGCCAGAATCCTGCCATGACAATGGGTTGGGATGCCGCCAAAGGTCAACTTGAAGTCAGACTCAATGATG
CCAACTGGCAGCAACCCACAGTGATTATCGATGGCGAGCCAGATACCACATTCAAGCTAGTGAGCTTAAAGCCAAGCGAA
AGTGATGCTAACGGCAAGCAATTGGTCGGTATTTTCAGCGGTAAAAGTTGGCTGGGCGAGTCTGAAGTTTTGGGTAAATC
GCTGAACATGACTGTCGCCGATAGCGAGCGAGCGTTGGAATACAGCGCCGAAGTTAAGCCTGTGGTGATTACCCAAGCAA
GTACCTCGATATTTGGCATGATTTTGTTAGCGCTTATCGGTGGTTTGATCTTAAACGTCATGCCCTGCGTGTTACCCGTT
CTCGGCATGAAGCTCAGTTCAGTGGTAGCTGCGCCTGATCTGAAGCGTAATCAAATCCGCCAACAGTTCATCGCATCAGC
GCTGGGGATATTGGCCTCATTCTGGTTACTGGCTGGCTTTATCTTAATGCTTAAGCTCACGGGTCAAGCGATTGGTTGGG
GTGTGCAGTTCCAAAACCCTTGGTTTATCGGCTTTATGGCGCTGGTGACCACAGTTTTTGCCTTCAATATGTTAGGTGTG
TTTGAGATCAACTTACCCTCTAACGTGCAAACCAAGTTGGCGACAACGGGCGGCAATAATAACAGCGGCCATTTTTTACA
GGGCATGTTTGCGACGCTGCTGGCGACACCGTGCAGTGCACCATTTTTGGGTACTGCAGTCGCCTTCGCCTTGGGCGCCG
ATGTACTTAGCCTGTTTGCCATCTTTACCGCGTTGGCCGTGGGTATGGCGTTCCCTTGGTTGATTGTGGCGGCATTTCCG
CAAGTGGCGGGTTATTTCCCCAAACCCGGTCGCTGGATGAATACAGTCAAAGTGTTTTTCTCCGGCATGTTGCTCATCAC
CAGTTTGTGGCTGATTAGCCTGTTGGCCAGCTTTATTGATGTGCTCTACCTGTGGCCGTTAGCGGGTGTCATTACACTGA
TATTTATGGTGTTTATGGCTAAAAAGTATGGCGCGATTGCCATCGTGAGCTGCTTAGGTATCGGCATTTTACTGTCGGCG
ATTATCGCATTTATGACGGCGAGCCAGTGGGCTAAACCTTTACCTGCGGATCTTGCTTGGACGCCATTGGATCAAGCATT
GATTAATCAGCAGGTGGTCCAAGGAAAAACTGTGTTTGTCGATGTGACGGCTGATTGGTGTATCACCTGTAAGGCCAATA
AAGTTGGCGTGATCTTGCAAGACCCTGTTTATAGCCTGTTGCAACAGCCGCATATTTTGCCGATGAAGGGCGATTGGACC
ACGCCTTCTGAGCCCATAACTCACTACCTGCAAAGCCATAATCGTTTCGGGGTGCCATTCAACGTGGTTTACGGCCCGGG
TGCGCCGCAAGGGATTGAGTTACCTGAAATTCTATCGACTGACCTTGTGCTTGCTGCGATTGAACAGGCCTCTGCGTCCC
CTGAAAAGTCATCCATAGCGGCAGGGAAATAA

Upstream 100 bases:

>100_bases
TTTTTCTTAAGCCATCACGCCCTTTGTAACGGGGGCAGAGTTAAGCAGTAAAGCAAGCATTTACAGGGCATAACGAACAG
TTCATGCCAATGGGGACAAA

Downstream 100 bases:

>100_bases
CGCTAACGACCAGCCGTTCACTCGGACATGTCACTCGGCAATATCACTGGCGAGTCTCATTCAATAGCGAGTCGAGTGAC
ACTCAACAAATACTCAGGTC

Product: cytochrome C biogenesis transmembrane protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MSTLKSMLTRFWILALIVTSPSLLAASTGWLVNDNHPPAKVRFMLTGEVDPTTNTLPAVLEVQLEGDWKTYWRSPGEGGI
APTIKWDGSHNLQQVDWRWPAPEEFSLLGLQTFGYKGNTTFPLTLKVDDIAAPTQLRGKVTLSTCTTICVLTDYQISLDF
TPNALQADTDAMLAYNKAVSLVPQKVLSQEGQNPAMTMGWDAAKGQLEVRLNDANWQQPTVIIDGEPDTTFKLVSLKPSE
SDANGKQLVGIFSGKSWLGESEVLGKSLNMTVADSERALEYSAEVKPVVITQASTSIFGMILLALIGGLILNVMPCVLPV
LGMKLSSVVAAPDLKRNQIRQQFIASALGILASFWLLAGFILMLKLTGQAIGWGVQFQNPWFIGFMALVTTVFAFNMLGV
FEINLPSNVQTKLATTGGNNNSGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFAIFTALAVGMAFPWLIVAAFP
QVAGYFPKPGRWMNTVKVFFSGMLLITSLWLISLLASFIDVLYLWPLAGVITLIFMVFMAKKYGAIAIVSCLGIGILLSA
IIAFMTASQWAKPLPADLAWTPLDQALINQQVVQGKTVFVDVTADWCITCKANKVGVILQDPVYSLLQQPHILPMKGDWT
TPSEPITHYLQSHNRFGVPFNVVYGPGAPQGIELPEILSTDLVLAAIEQASASPEKSSIAAGK

Sequences:

>Translated_703_residues
MSTLKSMLTRFWILALIVTSPSLLAASTGWLVNDNHPPAKVRFMLTGEVDPTTNTLPAVLEVQLEGDWKTYWRSPGEGGI
APTIKWDGSHNLQQVDWRWPAPEEFSLLGLQTFGYKGNTTFPLTLKVDDIAAPTQLRGKVTLSTCTTICVLTDYQISLDF
TPNALQADTDAMLAYNKAVSLVPQKVLSQEGQNPAMTMGWDAAKGQLEVRLNDANWQQPTVIIDGEPDTTFKLVSLKPSE
SDANGKQLVGIFSGKSWLGESEVLGKSLNMTVADSERALEYSAEVKPVVITQASTSIFGMILLALIGGLILNVMPCVLPV
LGMKLSSVVAAPDLKRNQIRQQFIASALGILASFWLLAGFILMLKLTGQAIGWGVQFQNPWFIGFMALVTTVFAFNMLGV
FEINLPSNVQTKLATTGGNNNSGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFAIFTALAVGMAFPWLIVAAFP
QVAGYFPKPGRWMNTVKVFFSGMLLITSLWLISLLASFIDVLYLWPLAGVITLIFMVFMAKKYGAIAIVSCLGIGILLSA
IIAFMTASQWAKPLPADLAWTPLDQALINQQVVQGKTVFVDVTADWCITCKANKVGVILQDPVYSLLQQPHILPMKGDWT
TPSEPITHYLQSHNRFGVPFNVVYGPGAPQGIELPEILSTDLVLAAIEQASASPEKSSIAAGK
>Mature_702_residues
STLKSMLTRFWILALIVTSPSLLAASTGWLVNDNHPPAKVRFMLTGEVDPTTNTLPAVLEVQLEGDWKTYWRSPGEGGIA
PTIKWDGSHNLQQVDWRWPAPEEFSLLGLQTFGYKGNTTFPLTLKVDDIAAPTQLRGKVTLSTCTTICVLTDYQISLDFT
PNALQADTDAMLAYNKAVSLVPQKVLSQEGQNPAMTMGWDAAKGQLEVRLNDANWQQPTVIIDGEPDTTFKLVSLKPSES
DANGKQLVGIFSGKSWLGESEVLGKSLNMTVADSERALEYSAEVKPVVITQASTSIFGMILLALIGGLILNVMPCVLPVL
GMKLSSVVAAPDLKRNQIRQQFIASALGILASFWLLAGFILMLKLTGQAIGWGVQFQNPWFIGFMALVTTVFAFNMLGVF
EINLPSNVQTKLATTGGNNNSGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFAIFTALAVGMAFPWLIVAAFPQ
VAGYFPKPGRWMNTVKVFFSGMLLITSLWLISLLASFIDVLYLWPLAGVITLIFMVFMAKKYGAIAIVSCLGIGILLSAI
IAFMTASQWAKPLPADLAWTPLDQALINQQVVQGKTVFVDVTADWCITCKANKVGVILQDPVYSLLQQPHILPMKGDWTT
PSEPITHYLQSHNRFGVPFNVVYGPGAPQGIELPEILSTDLVLAAIEQASASPEKSSIAAGK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=340, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 76053; Mature: 75921

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLKSMLTRFWILALIVTSPSLLAASTGWLVNDNHPPAKVRFMLTGEVDPTTNTLPAVL
CCHHHHHHHHHHHHHHHHCCCHHHEECCCCEEECCCCCCEEEEEEECCCCCCCCCCCEEE
EVQLEGDWKTYWRSPGEGGIAPTIKWDGSHNLQQVDWRWPAPEEFSLLGLQTFGYKGNTT
EEEECCCHHHHCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCEEEEEEEECCCCCCE
FPLTLKVDDIAAPTQLRGKVTLSTCTTICVLTDYQISLDFTPNALQADTDAMLAYNKAVS
EEEEEEECCCCCCCHHCCEEEHHHHEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
LVPQKVLSQEGQNPAMTMGWDAAKGQLEVRLNDANWQQPTVIIDGEPDTTFKLVSLKPSE
HHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCCC
SDANGKQLVGIFSGKSWLGESEVLGKSLNMTVADSERALEYSAEVKPVVITQASTSIFGM
CCCCCCEEEEEECCCCCCCCHHHCCCCCCEEEECCHHHHHHCCCCCEEEEECCCHHHHHH
ILLALIGGLILNVMPCVLPVLGMKLSSVVAAPDLKRNQIRQQFIASALGILASFWLLAGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILMLKLTGQAIGWGVQFQNPWFIGFMALVTTVFAFNMLGVFEINLPSNVQTKLATTGGNN
HHHHHHCCCHHEECEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEECCCCC
NSGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFAIFTALAVGMAFPWLIVAAFP
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVAGYFPKPGRWMNTVKVFFSGMLLITSLWLISLLASFIDVLYLWPLAGVITLIFMVFMA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYGAIAIVSCLGIGILLSAIIAFMTASQWAKPLPADLAWTPLDQALINQQVVQGKTVFV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEE
DVTADWCITCKANKVGVILQDPVYSLLQQPHILPMKGDWTTPSEPITHYLQSHNRFGVPF
EECCCEEEEEECCCEEEEECCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCEE
NVVYGPGAPQGIELPEILSTDLVLAAIEQASASPEKSSIAAGK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STLKSMLTRFWILALIVTSPSLLAASTGWLVNDNHPPAKVRFMLTGEVDPTTNTLPAVL
CHHHHHHHHHHHHHHHHCCCHHHEECCCCEEECCCCCCEEEEEEECCCCCCCCCCCEEE
EVQLEGDWKTYWRSPGEGGIAPTIKWDGSHNLQQVDWRWPAPEEFSLLGLQTFGYKGNTT
EEEECCCHHHHCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCEEEEEEEECCCCCCE
FPLTLKVDDIAAPTQLRGKVTLSTCTTICVLTDYQISLDFTPNALQADTDAMLAYNKAVS
EEEEEEECCCCCCCHHCCEEEHHHHEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
LVPQKVLSQEGQNPAMTMGWDAAKGQLEVRLNDANWQQPTVIIDGEPDTTFKLVSLKPSE
HHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCCC
SDANGKQLVGIFSGKSWLGESEVLGKSLNMTVADSERALEYSAEVKPVVITQASTSIFGM
CCCCCCEEEEEECCCCCCCCHHHCCCCCCEEEECCHHHHHHCCCCCEEEEECCCHHHHHH
ILLALIGGLILNVMPCVLPVLGMKLSSVVAAPDLKRNQIRQQFIASALGILASFWLLAGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILMLKLTGQAIGWGVQFQNPWFIGFMALVTTVFAFNMLGVFEINLPSNVQTKLATTGGNN
HHHHHHCCCHHEECEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEECCCCC
NSGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFAIFTALAVGMAFPWLIVAAFP
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVAGYFPKPGRWMNTVKVFFSGMLLITSLWLISLLASFIDVLYLWPLAGVITLIFMVFMA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKYGAIAIVSCLGIGILLSAIIAFMTASQWAKPLPADLAWTPLDQALINQQVVQGKTVFV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEE
DVTADWCITCKANKVGVILQDPVYSLLQQPHILPMKGDWTTPSEPITHYLQSHNRFGVPF
EECCCEEEEEECCCEEEEECCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCEE
NVVYGPGAPQGIELPEILSTDLVLAAIEQASASPEKSSIAAGK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA