Click here to switch to the map view.

The map label for this gene is cyoB [H]

Identifier: 160877453

GI number: 160877453

Start: 5144383

End: 5146362

Strand: Direct

Name: cyoB [H]

Synonym: Sbal195_4351

Alternate gene names: 160877453

Gene position: 5144383-5146362 (Clockwise)

Preceding gene: 160877452

Following gene: 160877454

Centisome position: 96.21

GC content: 48.89

Gene sequence:

>1980_bases
ATGTCATTTCTCGGTAAATTAAGCTTAGATGCGATTCCGTATCACGAGCCTATCATCATGGTGACCTTAGCGGTCGTCGC
AGTGGTAGGTTTGTATATCGCAGCCTTGATCACTAAACACAAAAAATGGAGCGTACTTTGGAACGACTGGTTAACCTCAG
TTGACCATAAACGCCTCGGTATCATGTACATAGTGTTAGCTTTGGTGATGCTCATTCGTGGCTTCTCCGATGCCATTATG
ATGCGTACCCAGCAAGCACTTGCCACCAACGGCGCCGCAGGTTATCTGCCGCCTGAACATTACGACCAAATCTTCACCGC
CCATGGCGTGATCATGATTATCTTTATGGCGATGCCATTTATGATAGGTCTAATGAACTTAGTGTTGCCGCTGCAAATTG
GTGCCCGCGACGTTGCCTTCCCATTCTTGAACAACCTCAGCTTCTGGCTTACCGCCTCGGGCGCTGTGCTGATCAATATT
TCTTTGGGTTTAGGTGAATTTGCTAAGACAGGTTGGGTGGCGTATCCACCCCTCTCAGAGCTGGCTTACAGTCCGGGGGT
TGGGGTCGATTACTATATCTGGGCACTGCAGATTTCGGGCATAGGGACGACCTTAACCGGGGTGAACTTTATCGCCACCG
TACTGAAGATGCGTGCCCCAGGCATGAAGCTGATGCAAATGCCAATCTTCACTTGGACTTGTACGTGGGCGAACATATTG
ATCGTCGCGTCATTCCCAATCTTAACCGCTGTGTTAGCCCTGCTGACACTCGACCGTTACATGGACTTCCACTTCTTCAC
CAATGACGGTGGCGGTAACGCCATGATGTATATCAACCTGTTTTGGGCGTGGGGACATCCTGAAGTTTACATCCTGATTT
TGCCTGCTTTTGGTATTTTCTCCGATGTGATCTCAACCTTTACCTCTAAACGTCTGTTCGGTTACACCTCTATGGTGTGG
GCGAGTGGTGCGATTTCAATTCTAGGTTTCATCGTTTGGTTACACCACTTCTTCACCATGGGCTCAAGTGCCAACGTCAA
CGCCTTCTTCGGGGTGATGACTATGGTGATTGCGGTTCCAACCGGGGTAAAACTGTTTAACTGGTTGTTCACTATCTACC
GTGGCCGCCTACGTTTAACGGTACCTGTGTTGTGGACGTTAGGCTTTATGGTGACTTTCACCATAGGCGGCATGACAGGT
GTGTTATTAGCCTTACCAGGTGCCGACTACGTTCTACATAACAGTTTGTTTTTAATCGCGCATTTCCATAACACTATTAT
TGGTGGTGCGGTATTTGGTTACTTAGCAGGCTTTGCTTACTGGTTCCCGAAAGCGACAGGTTTCCACTTGAATGAGCGTT
TAGGTAAAGCGTCATTCTGGTGCTGGCAAATCGGTTTCTATGTGGCCTTTATGCCGCTGTACGTACTGGGCTTTATGGGT
ATGACACGCCGTATCAACCACATTGATAACCCAGCGTGGAACGTGTGGATCTACTTAGCCGCCGTGGGTGCTTGCATCAT
CATGGTCGGTATCATTCTGCAGTTTATCCAACTGTACGTGAGTATCCGTGACCGCGACCAAAACCGCGACACCACGGGCG
ATCCATGGAATGGCCATACTTTAGAGTGGTCAACCGCTTCTCCACCGCAGTTCTATAACTTCGCTAAGCTGCCACAGGTT
GCTGATATTGATGCCTTTACCGATGCGAAAGAAAAAGGCGTGGCTTATCAACGTCAAAAACACTACCAAGCTATCCATAT
GCCGAAAAATACCCCAAGCGGTATCTTAATGGCGCTGGGGATCACTGCCGCGGGTTTTGCCGCTATTTGGCACATCCTGT
GGTTAGCCATTGTGGGCTTAGTGGGCGCTTTCGTGGTGTTCCTGTTCCGTGCTTATAACAATGACGTCGACTATTACGTG
CAACCCGATGAAGTGGCTCGCATTGAAAATGCCCACTTAAACAATGTAGTAAGGGGCTGA

Upstream 100 bases:

>100_bases
ATAGCTCAACACCTTCTGTACCGTCATCAACACAGGACTCATCCACAGAACCTTTATCCTTAGAGCACTCATCCACTCAA
AAAGTGGAGGCGGAGTAATC

Downstream 100 bases:

>100_bases
TATGAGTATTGCAATCCCAGCAGATTTAGAAGTAGCTCACGCAGAAGATCACCACGAACACCATGACACCAGTGGCAACA
CTCTGTTTGGTTTTTGGATT

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MSFLGKLSLDAIPYHEPIIMVTLAVVAVVGLYIAALITKHKKWSVLWNDWLTSVDHKRLGIMYIVLALVMLIRGFSDAIM
MRTQQALATNGAAGYLPPEHYDQIFTAHGVIMIIFMAMPFMIGLMNLVLPLQIGARDVAFPFLNNLSFWLTASGAVLINI
SLGLGEFAKTGWVAYPPLSELAYSPGVGVDYYIWALQISGIGTTLTGVNFIATVLKMRAPGMKLMQMPIFTWTCTWANIL
IVASFPILTAVLALLTLDRYMDFHFFTNDGGGNAMMYINLFWAWGHPEVYILILPAFGIFSDVISTFTSKRLFGYTSMVW
ASGAISILGFIVWLHHFFTMGSSANVNAFFGVMTMVIAVPTGVKLFNWLFTIYRGRLRLTVPVLWTLGFMVTFTIGGMTG
VLLALPGADYVLHNSLFLIAHFHNTIIGGAVFGYLAGFAYWFPKATGFHLNERLGKASFWCWQIGFYVAFMPLYVLGFMG
MTRRINHIDNPAWNVWIYLAAVGACIIMVGIILQFIQLYVSIRDRDQNRDTTGDPWNGHTLEWSTASPPQFYNFAKLPQV
ADIDAFTDAKEKGVAYQRQKHYQAIHMPKNTPSGILMALGITAAGFAAIWHILWLAIVGLVGAFVVFLFRAYNNDVDYYV
QPDEVARIENAHLNNVVRG

Sequences:

>Translated_659_residues
MSFLGKLSLDAIPYHEPIIMVTLAVVAVVGLYIAALITKHKKWSVLWNDWLTSVDHKRLGIMYIVLALVMLIRGFSDAIM
MRTQQALATNGAAGYLPPEHYDQIFTAHGVIMIIFMAMPFMIGLMNLVLPLQIGARDVAFPFLNNLSFWLTASGAVLINI
SLGLGEFAKTGWVAYPPLSELAYSPGVGVDYYIWALQISGIGTTLTGVNFIATVLKMRAPGMKLMQMPIFTWTCTWANIL
IVASFPILTAVLALLTLDRYMDFHFFTNDGGGNAMMYINLFWAWGHPEVYILILPAFGIFSDVISTFTSKRLFGYTSMVW
ASGAISILGFIVWLHHFFTMGSSANVNAFFGVMTMVIAVPTGVKLFNWLFTIYRGRLRLTVPVLWTLGFMVTFTIGGMTG
VLLALPGADYVLHNSLFLIAHFHNTIIGGAVFGYLAGFAYWFPKATGFHLNERLGKASFWCWQIGFYVAFMPLYVLGFMG
MTRRINHIDNPAWNVWIYLAAVGACIIMVGIILQFIQLYVSIRDRDQNRDTTGDPWNGHTLEWSTASPPQFYNFAKLPQV
ADIDAFTDAKEKGVAYQRQKHYQAIHMPKNTPSGILMALGITAAGFAAIWHILWLAIVGLVGAFVVFLFRAYNNDVDYYV
QPDEVARIENAHLNNVVRG
>Mature_658_residues
SFLGKLSLDAIPYHEPIIMVTLAVVAVVGLYIAALITKHKKWSVLWNDWLTSVDHKRLGIMYIVLALVMLIRGFSDAIMM
RTQQALATNGAAGYLPPEHYDQIFTAHGVIMIIFMAMPFMIGLMNLVLPLQIGARDVAFPFLNNLSFWLTASGAVLINIS
LGLGEFAKTGWVAYPPLSELAYSPGVGVDYYIWALQISGIGTTLTGVNFIATVLKMRAPGMKLMQMPIFTWTCTWANILI
VASFPILTAVLALLTLDRYMDFHFFTNDGGGNAMMYINLFWAWGHPEVYILILPAFGIFSDVISTFTSKRLFGYTSMVWA
SGAISILGFIVWLHHFFTMGSSANVNAFFGVMTMVIAVPTGVKLFNWLFTIYRGRLRLTVPVLWTLGFMVTFTIGGMTGV
LLALPGADYVLHNSLFLIAHFHNTIIGGAVFGYLAGFAYWFPKATGFHLNERLGKASFWCWQIGFYVAFMPLYVLGFMGM
TRRINHIDNPAWNVWIYLAAVGACIIMVGIILQFIQLYVSIRDRDQNRDTTGDPWNGHTLEWSTASPPQFYNFAKLPQVA
DIDAFTDAKEKGVAYQRQKHYQAIHMPKNTPSGILMALGITAAGFAAIWHILWLAIVGLVGAFVVFLFRAYNNDVDYYVQ
PDEVARIENAHLNNVVRG

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=38.5964912280702, Blast_Score=342, Evalue=8e-94,
Organism=Escherichia coli, GI1786634, Length=655, Percent_Identity=67.0229007633588, Blast_Score=938, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=484, Percent_Identity=40.2892561983471, Blast_Score=345, Evalue=9e-96,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=41.7956656346749, Blast_Score=242, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=34.9593495934959, Blast_Score=130, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 73558; Mature: 73426

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLGKLSLDAIPYHEPIIMVTLAVVAVVGLYIAALITKHKKWSVLWNDWLTSVDHKRLG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHH
IMYIVLALVMLIRGFSDAIMMRTQQALATNGAAGYLPPEHYDQIFTAHGVIMIIFMAMPF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MIGLMNLVLPLQIGARDVAFPFLNNLSFWLTASGAVLINISLGLGEFAKTGWVAYPPLSE
HHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCEEEEEEECCCCHHHHCCCEECCCHHH
LAYSPGVGVDYYIWALQISGIGTTLTGVNFIATVLKMRAPGMKLMQMPIFTWTCTWANIL
HCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEHHHHHHH
IVASFPILTAVLALLTLDRYMDFHFFTNDGGGNAMMYINLFWAWGHPEVYILILPAFGIF
HHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEEECCCCEEEEEECHHHHH
SDVISTFTSKRLFGYTSMVWASGAISILGFIVWLHHFFTMGSSANVNAFFGVMTMVIAVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
TGVKLFNWLFTIYRGRLRLTVPVLWTLGFMVTFTIGGMTGVLLALPGADYVLHNSLFLIA
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEHHCCEEEEE
HFHNTIIGGAVFGYLAGFAYWFPKATGFHLNERLGKASFWCWQIGFYVAFMPLYVLGFMG
EHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MTRRINHIDNPAWNVWIYLAAVGACIIMVGIILQFIQLYVSIRDRDQNRDTTGDPWNGHT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LEWSTASPPQFYNFAKLPQVADIDAFTDAKEKGVAYQRQKHYQAIHMPKNTPSGILMALG
EEECCCCCCCCCCHHCCCCCCCCCHHCCCHHCCCHHHHHHCCCEEECCCCCCCCHHHHHH
ITAAGFAAIWHILWLAIVGLVGAFVVFLFRAYNNDVDYYVQPDEVARIENAHLNNVVRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFLGKLSLDAIPYHEPIIMVTLAVVAVVGLYIAALITKHKKWSVLWNDWLTSVDHKRLG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHH
IMYIVLALVMLIRGFSDAIMMRTQQALATNGAAGYLPPEHYDQIFTAHGVIMIIFMAMPF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MIGLMNLVLPLQIGARDVAFPFLNNLSFWLTASGAVLINISLGLGEFAKTGWVAYPPLSE
HHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCEEEEEEECCCCHHHHCCCEECCCHHH
LAYSPGVGVDYYIWALQISGIGTTLTGVNFIATVLKMRAPGMKLMQMPIFTWTCTWANIL
HCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEHHHHHHH
IVASFPILTAVLALLTLDRYMDFHFFTNDGGGNAMMYINLFWAWGHPEVYILILPAFGIF
HHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEEECCCCEEEEEECHHHHH
SDVISTFTSKRLFGYTSMVWASGAISILGFIVWLHHFFTMGSSANVNAFFGVMTMVIAVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
TGVKLFNWLFTIYRGRLRLTVPVLWTLGFMVTFTIGGMTGVLLALPGADYVLHNSLFLIA
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEHHCCEEEEE
HFHNTIIGGAVFGYLAGFAYWFPKATGFHLNERLGKASFWCWQIGFYVAFMPLYVLGFMG
EHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MTRRINHIDNPAWNVWIYLAAVGACIIMVGIILQFIQLYVSIRDRDQNRDTTGDPWNGHT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LEWSTASPPQFYNFAKLPQVADIDAFTDAKEKGVAYQRQKHYQAIHMPKNTPSGILMALG
EEECCCCCCCCCCHHCCCCCCCCCHHCCCHHCCCHHHHHHCCCEEECCCCCCCCHHHHHH
ITAAGFAAIWHILWLAIVGLVGAFVVFLFRAYNNDVDYYVQPDEVARIENAHLNNVVRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]