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The map label for this gene is ctaD [H]

Identifier: 160877414

GI number: 160877414

Start: 5095587

End: 5097179

Strand: Direct

Name: ctaD [H]

Synonym: Sbal195_4312

Alternate gene names: 160877414

Gene position: 5095587-5097179 (Clockwise)

Preceding gene: 160877413

Following gene: 160877415

Centisome position: 95.29

GC content: 50.22

Gene sequence:

>1593_bases
ATGAGCACAACGACTCAAGATCAAACCGCAGCCCATGATGACCATCATCATGGTGCGCCAAAGGGCATCATGCGCTGGGT
GCTAACCACCAACCATAAAGACATTGGTACTTTGTATTTATGGTTCAGCTTCATTATGTTTTTAACCGGTGGCGCTATGG
CCATGGTGATCCGCGCTGAACTCTTTCAGCCCGGATTACAATTGGTCGAGCCCAACTTCTTTAACCAAATGACCACAGTG
CATGGGCTGATCATGGTATTCGGCGCGGTAATGCCCGCCTTTACTGGGCTCGCAAACTGGCTGATCCCTATGATGATTGG
TGCGCCCGATATGGCGCTACCACGGATGAATAACTGGAGTTTTTGGATCTTACCCTTCGCCTTTACCATCCTACTCAGCT
CGCTGTTTATGGAAGGCGGCGGACCTAACTTTGGTTGGACCTTCTACGCGCCACTGTCTACCACTTATAGTCCTGACAGC
ACGGCACTCTTCGTGTTCTCTATTCATATCATGGGGATAAGTTCGATCATGGGTGCAATCAACGTGATTGTAACCATAGT
GAATTTACGTGCGCCCGGTATGACATGGATGAAGTTGCCTCTGTTTGTATGGACTTGGCTTATCACAGCATTCCTGCTGA
TCGCTGTGATGCCCGTACTTGCGGGCGCTGTGACTATGGTACTGACCGATAAGTTTTTCGGCACTAGCTTCTTCGAAGCG
GCAGGCGGCGGCGATCCTGTGATGTTCCAGCATATTTTCTGGTTCTTCGGCCACCCTGAAGTCTACATCATGATTTTGCC
GTCCTTTGGCATCATCTCCGCCATAGTACCCGCTTTCAGCCGTAAACCATTATTCGGCTATGCATCAATGGTTTATGCCA
CTGCCAGTATTGCAATTCTGTCGTTCCTCGTGTGGGCGCACCACATGTTCACTACAGGCATGCCAGTGTTTGCCGAGCTG
TTCTTCATGTATTGCACTATGTTGATTGCGGTACCAACGGGGGTGAAAGTGTTTAACTGGGTCGCAACTATGTGGCGTGG
TTCACTCAGCTTCGAAACCCCTATGTTGTTCGCCGTGGCCTTTATCATACTCTTCACCATTGGCGGGTTTTCGGGGTTAA
TGCTCGCCATTACGCCAGCCGACTTCCAATACCACGACACCTACTTTGTGGTGGCGCATTTCCATTATGTGCTCGTGACT
GGGGCGATTTTCTCCATCATGGCGGCAGCCTATTACTGGCTCCCTAAATGGACGGGGCACATGTACAACGAGCGACTGGG
GCAATGGCATTTCTGGTGTTCGGTGATTTCGGTCAACGTACTGTTTTTCCCGATGCATTTCCTTGGGCTCGCAGGTATGC
CAAGGCGTATCCCCGATTACTCGATTCAATTTGCCGATGTTAATCAAATCGTTTCGATTGGTGGCTTCGCCTTCGGCTTA
TCGCAATTGATTTTTTTAGTGTTAGTGATCAAGTGCATCCGTGGCGGCGAAAAAGCCCCCGCTAAACCTTGGGAAGGTTC
CGAGGGTTTAGAGTGGACATTGCCAAGCCCAGCGCCTTATCACTCCTTCACGACACCACCTGAGGTGAAATGA

Upstream 100 bases:

>100_bases
CGCAGCAGTCATTACCTATGAGCGCAATGCTTGGGGCAACAATACCGGCGATACAGTGCAACCTGCTGATATCGCAAGCC
ATGGACAGTAAGGGATTATG

Downstream 100 bases:

>100_bases
AATGACGAACCATCACCAGCCAGAAAAACCTAAGTCAAATCGAAAGCTTATCAGCATGCTCGTCATGGGCTGTATTGGTA
TGTTTGGTTTTGGGTTCGCG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MSTTTQDQTAAHDDHHHGAPKGIMRWVLTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAELFQPGLQLVEPNFFNQMTTV
HGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDS
TALFVFSIHIMGISSIMGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGAVTMVLTDKFFGTSFFEA
AGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKPLFGYASMVYATASIAILSFLVWAHHMFTTGMPVFAEL
FFMYCTMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVT
GAIFSIMAAAYYWLPKWTGHMYNERLGQWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYSIQFADVNQIVSIGGFAFGL
SQLIFLVLVIKCIRGGEKAPAKPWEGSEGLEWTLPSPAPYHSFTTPPEVK

Sequences:

>Translated_530_residues
MSTTTQDQTAAHDDHHHGAPKGIMRWVLTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAELFQPGLQLVEPNFFNQMTTV
HGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDS
TALFVFSIHIMGISSIMGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGAVTMVLTDKFFGTSFFEA
AGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKPLFGYASMVYATASIAILSFLVWAHHMFTTGMPVFAEL
FFMYCTMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVT
GAIFSIMAAAYYWLPKWTGHMYNERLGQWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYSIQFADVNQIVSIGGFAFGL
SQLIFLVLVIKCIRGGEKAPAKPWEGSEGLEWTLPSPAPYHSFTTPPEVK
>Mature_529_residues
STTTQDQTAAHDDHHHGAPKGIMRWVLTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAELFQPGLQLVEPNFFNQMTTVH
GLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWSFWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDST
ALFVFSIHIMGISSIMGAINVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGAVTMVLTDKFFGTSFFEAA
GGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKPLFGYASMVYATASIAILSFLVWAHHMFTTGMPVFAELF
FMYCTMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVAFIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTG
AIFSIMAAAYYWLPKWTGHMYNERLGQWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYSIQFADVNQIVSIGGFAFGLS
QLIFLVLVIKCIRGGEKAPAKPWEGSEGLEWTLPSPAPYHSFTTPPEVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=49.0196078431373, Blast_Score=447, Evalue=1e-125,
Organism=Escherichia coli, GI1786634, Length=514, Percent_Identity=39.2996108949416, Blast_Score=357, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=48.3018867924528, Blast_Score=481, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=50, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6226523, Length=248, Percent_Identity=45.9677419354839, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59225; Mature: 59093

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTTQDQTAAHDDHHHGAPKGIMRWVLTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
LFQPGLQLVEPNFFNQMTTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWS
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDSTALFVFSIHIMGISSIMGAI
EEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
NVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGAVTMVLTDKFFGTSFFEA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKPLFGYASMVYATASIAIL
CCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
FIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTGAIFSIMAAAYYWLPKWTGH
HHHHHHHCCCCCEEEEEECCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
MYNERLGQWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYSIQFADVNQIVSIGGFAFGL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
SQLIFLVLVIKCIRGGEKAPAKPWEGSEGLEWTLPSPAPYHSFTTPPEVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STTTQDQTAAHDDHHHGAPKGIMRWVLTTNHKDIGTLYLWFSFIMFLTGGAMAMVIRAE
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
LFQPGLQLVEPNFFNQMTTVHGLIMVFGAVMPAFTGLANWLIPMMIGAPDMALPRMNNWS
HHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FWILPFAFTILLSSLFMEGGGPNFGWTFYAPLSTTYSPDSTALFVFSIHIMGISSIMGAI
EEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
NVIVTIVNLRAPGMTWMKLPLFVWTWLITAFLLIAVMPVLAGAVTMVLTDKFFGTSFFEA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKPLFGYASMVYATASIAIL
CCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SFLVWAHHMFTTGMPVFAELFFMYCTMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
FIILFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTGAIFSIMAAAYYWLPKWTGH
HHHHHHHCCCCCEEEEEECCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
MYNERLGQWHFWCSVISVNVLFFPMHFLGLAGMPRRIPDYSIQFADVNQIVSIGGFAFGL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
SQLIFLVLVIKCIRGGEKAPAKPWEGSEGLEWTLPSPAPYHSFTTPPEVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]