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The map label for this gene is ctaC [H]

Identifier: 160877413

GI number: 160877413

Start: 5094021

End: 5095577

Strand: Direct

Name: ctaC [H]

Synonym: Sbal195_4311

Alternate gene names: 160877413

Gene position: 5094021-5095577 (Clockwise)

Preceding gene: 160877412

Following gene: 160877414

Centisome position: 95.26

GC content: 52.02

Gene sequence:

>1557_bases
GTGAAGCAATTGTTGTATTGTTTACTCGTGGTGTTATTCGCACCACCGTTGGCCGCCGCGGACATGCGGTTCAACATGAC
CCCTGGCGTAACCGAGATCAGTGGCAAGGTTTATCACTTGCACATGACCATCTTGTATATCTGCTGCGCCATTGGCCTTG
TGGTCTTTGGCGTGATGATTTACGCCATGATCAACCACAGAAAATCCAAAGGCGCTGTCGCGTCCCACTTTCACGAAAGC
ACTAAAGTTGAAATAGCTTGGACTATTCTGCCATTTATCATTTTGATCTTAATGGCGATTCCAGCGACAAAAACCTTAAT
TGCGATGGAAGATCCCAGCGACGCCGATCTGACCGTTAAAGTCACGGGTTCCCAATGGAAATGGCATTACAGCTATTTCG
ATCAAGACATTGATTTTTACAGCATACTCGCAACCCCTAGAGCCCAAATCGACGGTACCGAAACCAAGGGTGAACACTAC
CTATTGGAAGTCGATAAGCCGCTCGTACTGCCGATAAATCGCAAAATCCGCTTTTTGATGACCTCTGAAGATGTCATCCA
TTCATGGTGGGTACCTGCTTTTGCCGTGAAGAAAGATGCCAACCCAGGATTTATCAATGAGGCTTGGACTCGCATCGACA
AACCCGGTATTTACCGTGGTCAATGCGCCGAACTTTGCGGTAAAGATCATGGTTTTATGCCGATTGTAGTGAAAGCCTTA
CCCGAAGCCGAGTTTGAAGCTTGGGTAGCGGAGCAGAAACAAGCCGCGGGCGCGGCGGCAGAAGCGGCTCAAGCCGCTTT
ATCACAGACTCTTAGCAAAGATGATCTGATGACCCAAGGTGAGCAAGTTTACCTCGGGCACTGCGCAGCCTGTCACCAGC
CCAATGGCGAGGGTTTACAAGGCGTATTCCCACACCTCAAAGGCAGCCCGATAGCAACGGGACCGCTCAGCGGCCACCTT
GAAATCGTACTCAACGGTAAAACGGGTACGGCTATGCAAGCCTTTGGCAAGCAATTGAGCGCACAAGAAATTGCCGCTGT
GATTACCTATGAGCGTAATGCTTGGGGCAATAATACTGGCGATGCTGTGCAGGCCAAAGATGTCAATGAGCACATGAACG
GTAGTGCAGGCACACAGGCACCTGCTACCGCACCAGCCAATACGACCCCAACTCCCGCACCTACAACTGAGCCCGCAGCA
GTTGTCGACTCCGCAACCATAGTCGATCCGGCGAGTCTCCCCACGCTCACCCATGAGGCACTGATGGCCGAAGGTGAAAC
TGTCTACACCACCACTTGTGCGGCCTGCCATCAGTTAACGGGAGCTGGCATACCACCCGCCTTCCCCGCCCTCGCTGGCA
GTGCTATCGCCACTGGGCCCGTCGCCAATCATCTCGATATTGTGATGCTCGGCAAAACAGGCACGGCTATGCAAGCATTT
GGCAAACAACTCAGCCCACAGCAACTCGCAGCAGTCATTACCTATGAGCGCAATGCTTGGGGCAACAATACCGGCGATAC
AGTGCAACCTGCTGATATCGCAAGCCATGGACAGTAA

Upstream 100 bases:

>100_bases
AAAAAGCTTTTTTGGGAACTGAAGAGTTTGCATAGAGTTGAGACTTACTGTGTTGCTCTTCTTTGTAGTTGCTATTCGCA
ATTGGCAGAGGAGAAGTCTT

Downstream 100 bases:

>100_bases
GGGATTATGATGAGCACAACGACTCAAGATCAAACCGCAGCCCATGATGACCATCATCATGGTGCGCCAAAGGGCATCAT
GCGCTGGGTGCTAACCACCA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MKQLLYCLLVVLFAPPLAAADMRFNMTPGVTEISGKVYHLHMTILYICCAIGLVVFGVMIYAMINHRKSKGAVASHFHES
TKVEIAWTILPFIILILMAIPATKTLIAMEDPSDADLTVKVTGSQWKWHYSYFDQDIDFYSILATPRAQIDGTETKGEHY
LLEVDKPLVLPINRKIRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYRGQCAELCGKDHGFMPIVVKAL
PEAEFEAWVAEQKQAAGAAAEAAQAALSQTLSKDDLMTQGEQVYLGHCAACHQPNGEGLQGVFPHLKGSPIATGPLSGHL
EIVLNGKTGTAMQAFGKQLSAQEIAAVITYERNAWGNNTGDAVQAKDVNEHMNGSAGTQAPATAPANTTPTPAPTTEPAA
VVDSATIVDPASLPTLTHEALMAEGETVYTTTCAACHQLTGAGIPPAFPALAGSAIATGPVANHLDIVMLGKTGTAMQAF
GKQLSPQQLAAVITYERNAWGNNTGDTVQPADIASHGQ

Sequences:

>Translated_518_residues
MKQLLYCLLVVLFAPPLAAADMRFNMTPGVTEISGKVYHLHMTILYICCAIGLVVFGVMIYAMINHRKSKGAVASHFHES
TKVEIAWTILPFIILILMAIPATKTLIAMEDPSDADLTVKVTGSQWKWHYSYFDQDIDFYSILATPRAQIDGTETKGEHY
LLEVDKPLVLPINRKIRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYRGQCAELCGKDHGFMPIVVKAL
PEAEFEAWVAEQKQAAGAAAEAAQAALSQTLSKDDLMTQGEQVYLGHCAACHQPNGEGLQGVFPHLKGSPIATGPLSGHL
EIVLNGKTGTAMQAFGKQLSAQEIAAVITYERNAWGNNTGDAVQAKDVNEHMNGSAGTQAPATAPANTTPTPAPTTEPAA
VVDSATIVDPASLPTLTHEALMAEGETVYTTTCAACHQLTGAGIPPAFPALAGSAIATGPVANHLDIVMLGKTGTAMQAF
GKQLSPQQLAAVITYERNAWGNNTGDTVQPADIASHGQ
>Mature_518_residues
MKQLLYCLLVVLFAPPLAAADMRFNMTPGVTEISGKVYHLHMTILYICCAIGLVVFGVMIYAMINHRKSKGAVASHFHES
TKVEIAWTILPFIILILMAIPATKTLIAMEDPSDADLTVKVTGSQWKWHYSYFDQDIDFYSILATPRAQIDGTETKGEHY
LLEVDKPLVLPINRKIRFLMTSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYRGQCAELCGKDHGFMPIVVKAL
PEAEFEAWVAEQKQAAGAAAEAAQAALSQTLSKDDLMTQGEQVYLGHCAACHQPNGEGLQGVFPHLKGSPIATGPLSGHL
EIVLNGKTGTAMQAFGKQLSAQEIAAVITYERNAWGNNTGDAVQAKDVNEHMNGSAGTQAPATAPANTTPTPAPTTEPAA
VVDSATIVDPASLPTLTHEALMAEGETVYTTTCAACHQLTGAGIPPAFPALAGSAIATGPVANHLDIVMLGKTGTAMQAF
GKQLSPQQLAAVITYERNAWGNNTGDTVQPADIASHGQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=168, Percent_Identity=41.0714285714286, Blast_Score=144, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6226540, Length=223, Percent_Identity=30.9417040358744, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 55408; Mature: 55408

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLLYCLLVVLFAPPLAAADMRFNMTPGVTEISGKVYHLHMTILYICCAIGLVVFGVMI
CHHHHHHHHHHHHCCCCHHCCEEECCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVASHFHESTKVEIAWTILPFIILILMAIPATKTLIAMEDPSDADLTVK
HHHHHCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
VTGSQWKWHYSYFDQDIDFYSILATPRAQIDGTETKGEHYLLEVDKPLVLPINRKIRFLM
EECCCEEEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCEEEECCCEEEEEE
TSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYRGQCAELCGKDHGFMPIVVKAL
ECHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHEECC
PEAEFEAWVAEQKQAAGAAAEAAQAALSQTLSKDDLMTQGEQVYLGHCAACHQPNGEGLQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEHCCCCCCCCCCH
GVFPHLKGSPIATGPLSGHLEIVLNGKTGTAMQAFGKQLSAQEIAAVITYERNAWGNNTG
HHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCHHHEEEEEEEECCCCCCCCC
DAVQAKDVNEHMNGSAGTQAPATAPANTTPTPAPTTEPAAVVDSATIVDPASLPTLTHEA
CCEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHH
LMAEGETVYTTTCAACHQLTGAGIPPAFPALAGSAIATGPVANHLDIVMLGKTGTAMQAF
HHHCCCEEEEEHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
GKQLSPQQLAAVITYERNAWGNNTGDTVQPADIASHGQ
HCCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQLLYCLLVVLFAPPLAAADMRFNMTPGVTEISGKVYHLHMTILYICCAIGLVVFGVMI
CHHHHHHHHHHHHCCCCHHCCEEECCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVASHFHESTKVEIAWTILPFIILILMAIPATKTLIAMEDPSDADLTVK
HHHHHCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
VTGSQWKWHYSYFDQDIDFYSILATPRAQIDGTETKGEHYLLEVDKPLVLPINRKIRFLM
EECCCEEEEEEHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCEEEECCCEEEEEE
TSEDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYRGQCAELCGKDHGFMPIVVKAL
ECHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHEECC
PEAEFEAWVAEQKQAAGAAAEAAQAALSQTLSKDDLMTQGEQVYLGHCAACHQPNGEGLQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEHCCCCCCCCCCH
GVFPHLKGSPIATGPLSGHLEIVLNGKTGTAMQAFGKQLSAQEIAAVITYERNAWGNNTG
HHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCHHHEEEEEEEECCCCCCCCC
DAVQAKDVNEHMNGSAGTQAPATAPANTTPTPAPTTEPAAVVDSATIVDPASLPTLTHEA
CCEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHH
LMAEGETVYTTTCAACHQLTGAGIPPAFPALAGSAIATGPVANHLDIVMLGKTGTAMQAF
HHHCCCEEEEEHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
GKQLSPQQLAAVITYERNAWGNNTGDTVQPADIASHGQ
HCCCCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA