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The map label for this gene is gmhA [H]

Identifier: 160877292

GI number: 160877292

Start: 4955853

End: 4956446

Strand: Direct

Name: gmhA [H]

Synonym: Sbal195_4189

Alternate gene names: 160877292

Gene position: 4955853-4956446 (Clockwise)

Preceding gene: 160877291

Following gene: 160877293

Centisome position: 92.68

GC content: 50.84

Gene sequence:

>594_bases
ATGTTAGAACGCATTAAAGACAGCTTTACTGAATCTATCCAGACAAAAATCGATGCAGCCGAAGCACTGCCAGAATCAAT
CGCCAAAGCGGCCGAGATGATGGTGCACTGTCTTTTGGGTGGCAATAAAATCCTTGCTTGCGGTAACGGCGGCAGTGCTG
GCGATGCACAACATTTCTCAGCCGAACTGCTAAACCGCTACGAGATTGAACGTCCACCCTTACCGGCCATCGCCCTGTCT
ACTGACACTTCAACCATCACAGCTATCGCCAACGACTATAGCTATGATGAGATTTTCTCAAAACAGATTTTTGCCTTAGG
TCAACCGGGCGACATTCTGCTGGCAATCTCCACCAGCGGTAACTCAGGTAACGTGATTAAAGCCATGGAAGCCGCATTAA
GCCGCGACATGACGATCGTTGCACTAACAGGTAAAGATGGGGGCGCTATGGCAGGCCTGCTGAGCGTGGGCGATGTGGAA
ATCCGCGTTCCTTCAAACGTCACCGCACGTATTCAAGAAGTGCACTTACTGGTGATCCACTGCCTGTGTGACAACATTGA
CCGCACACTCTTCCCGCAGGACGAGCAGCAATGA

Upstream 100 bases:

>100_bases
GTGCGAGAGTAGCAACACAAATTATTTTTAACGTCTGTGCCTCAACACGCTTGTGGAAATATGGCATGATAGCAACACTT
TATCCTGAAAGGATTTATCC

Downstream 100 bases:

>100_bases
GACATGCTGCCCCGCTGTTAATGGTTTGCTTGCTGCTACAAGGCTGCGCCGGTGCCGTTATGGTGGGCGCAGTGAGTGGC
GCTATGATGGCCAACGATGA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MLERIKDSFTESIQTKIDAAEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALS
TDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVALTGKDGGAMAGLLSVGDVE
IRVPSNVTARIQEVHLLVIHCLCDNIDRTLFPQDEQQ

Sequences:

>Translated_197_residues
MLERIKDSFTESIQTKIDAAEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALS
TDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVALTGKDGGAMAGLLSVGDVE
IRVPSNVTARIQEVHLLVIHCLCDNIDRTLFPQDEQQ
>Mature_197_residues
MLERIKDSFTESIQTKIDAAEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALS
TDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVALTGKDGGAMAGLLSVGDVE
IRVPSNVTARIQEVHLLVIHCLCDNIDRTLFPQDEQQ

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=195, Percent_Identity=64.1025641025641, Blast_Score=264, Evalue=4e-72,
Organism=Escherichia coli, GI1786416, Length=167, Percent_Identity=49.7005988023952, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20989; Mature: 20989

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERIKDSFTESIQTKIDAAEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
AELLNRYEIERPPLPAIALSTDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSG
HHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCC
NSGNVIKAMEAALSRDMTIVALTGKDGGAMAGLLSVGDVEIRVPSNVTARIQEVHLLVIH
CCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHH
CLCDNIDRTLFPQDEQQ
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLERIKDSFTESIQTKIDAAEALPESIAKAAEMMVHCLLGGNKILACGNGGSAGDAQHFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
AELLNRYEIERPPLPAIALSTDTSTITAIANDYSYDEIFSKQIFALGQPGDILLAISTSG
HHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCC
NSGNVIKAMEAALSRDMTIVALTGKDGGAMAGLLSVGDVEIRVPSNVTARIQEVHLLVIH
CCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHH
CLCDNIDRTLFPQDEQQ
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA