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The map label for this gene is aprE [H]

Identifier: 160877204

GI number: 160877204

Start: 4854201

End: 4855583

Strand: Direct

Name: aprE [H]

Synonym: Sbal195_4100

Alternate gene names: 160877204

Gene position: 4854201-4855583 (Clockwise)

Preceding gene: 160877203

Following gene: 160877205

Centisome position: 90.78

GC content: 45.41

Gene sequence:

>1383_bases
ATGAGTAAAAATTTAACCGCAAATGACTTAGACATGGTTGATGATGTCTACGGCGCCATGATGACGGACGCTCCCAGCGG
ACACAGGTTAATCATATGGGCACTTGCAGCTATGGTTGTGTGTTTTTTACTGTGGGCAGGTTTTGCTAAATTAGACAAGG
TCACCACTGGGACAGGTAAAGTCATCCCCTCATCACAAGTCCAAGTCATCCAGAGTTTAGATGGCGGCATAATGCAAGAG
CTCTACGTTCAGGAAGGTGAAATGGTGACTAAAGGGCAACCTTTAGTGCGTATTGATGATACCCGCTTCCGCTCCGACTA
TGCTCAACAAGAGCAAGAAGTTTTTGGCTTAAAAACCAATGCTATTCGTATGCGCGCCGAACTCGACAGCATTCTCATAT
CAGACATGACTTCTGACTGGCGCGAGCAAGTACTCATTACTAAAAAAGCATTGGTATTCCCGGAGAATATTATTGCAGCG
GAACCGGCATTAGTTAAAAGACAACAAGAGGAATACAACGGACGCTTAGATAACTTAAGTAACCAGCTTGAAATCCTGGT
CCGTCAAATTCAACAAAGACAACAAGAAATTGATGATCTCGCGTCTAAAACAACGACATTAACCACCAGTATGCAGCTGA
TCTCCCGTGAGCTTGAACTCACTCGGCCTTTAGCTAAAAAAGGTATCGTGCCTGAAGTTGAACTGCTCAAGCTCGAACGC
ACAGTGAACGATTTGCAAGGCGAATTGAATTCAATGCGCCTACTGCGCCCGAAAGTCAAAGCGGCGATGGATGAAGCCAT
CTTAAAACGCCGTGAAGCCGTATTCGTTTATGCCGCCGATCTACGCGCACAGCTTAATGAAACCCAAACCCGCCTGTCTC
GCATGAATGAAGCACAAGTGGGCGCACAGGATAAAGTCAGCAAAGCCATTATCACCTCACCAGTCAATGGCACCATTAAA
ACCACTCACATCAATACACTAGGCGGCGTTGTGCAACCTGGAGTCGATATTATCGAGATAGTGCCATCGGAAGATCAGTT
ACTGATTGAAACCAAAATCTTGCCTAAAGATATCGCCTTCTTACACCCAGGATTACCCGCAGTGGTAAAGATTACCGCCT
ATGACTTTACTCGCTATGGCGGCCTTAAAGGGACAGTTGAACATATCAGTGCCGACACATCCCAAGATGAAGAAGGCAAT
AGCTATTATCTCATTCGAGTCAGAACCGCAGAATCCAGTTTAACCAAAAACGATGGCACACAGATGCCAATTATCCCGGG
AATGTTAACTTCGGTTGACGTTATCACGGGGCAAAGATCCATACTTGAGTACATTTTAAATCCAATTTTAAGGGCTAAGG
ACACAGCGCTAAGAGAGCACTAA

Upstream 100 bases:

>100_bases
GTATTATCGTACTCGAGCGCGGCCATGTGGTCGCCGATGGTCCCAAGGCAGAAGTGTTAGAAAAACTCAATTTTGGCCTC
GTGAATGGAGAAGCTAAAAG

Downstream 100 bases:

>100_bases
GCCTTTTTTTATAAACCGGGAGGTTGGTCATGAAGACTTCAGCAAGACGACAATTTCAATGTTCAAAGATAGCCATAGTG
CTGTCATTGATCCTGTTACC

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSKNLTANDLDMVDDVYGAMMTDAPSGHRLIIWALAAMVVCFLLWAGFAKLDKVTTGTGKVIPSSQVQVIQSLDGGIMQE
LYVQEGEMVTKGQPLVRIDDTRFRSDYAQQEQEVFGLKTNAIRMRAELDSILISDMTSDWREQVLITKKALVFPENIIAA
EPALVKRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
TVNDLQGELNSMRLLRPKVKAAMDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAIITSPVNGTIK
TTHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHPGLPAVVKITAYDFTRYGGLKGTVEHISADTSQDEEGN
SYYLIRVRTAESSLTKNDGTQMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALREH

Sequences:

>Translated_460_residues
MSKNLTANDLDMVDDVYGAMMTDAPSGHRLIIWALAAMVVCFLLWAGFAKLDKVTTGTGKVIPSSQVQVIQSLDGGIMQE
LYVQEGEMVTKGQPLVRIDDTRFRSDYAQQEQEVFGLKTNAIRMRAELDSILISDMTSDWREQVLITKKALVFPENIIAA
EPALVKRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
TVNDLQGELNSMRLLRPKVKAAMDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAIITSPVNGTIK
TTHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHPGLPAVVKITAYDFTRYGGLKGTVEHISADTSQDEEGN
SYYLIRVRTAESSLTKNDGTQMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALREH
>Mature_459_residues
SKNLTANDLDMVDDVYGAMMTDAPSGHRLIIWALAAMVVCFLLWAGFAKLDKVTTGTGKVIPSSQVQVIQSLDGGIMQEL
YVQEGEMVTKGQPLVRIDDTRFRSDYAQQEQEVFGLKTNAIRMRAELDSILISDMTSDWREQVLITKKALVFPENIIAAE
PALVKRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLERT
VNDLQGELNSMRLLRPKVKAAMDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAIITSPVNGTIKT
THINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHPGLPAVVKITAYDFTRYGGLKGTVEHISADTSQDEEGNS
YYLIRVRTAESSLTKNDGTQMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALREH

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51270; Mature: 51139

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNLTANDLDMVDDVYGAMMTDAPSGHRLIIWALAAMVVCFLLWAGFAKLDKVTTGTGK
CCCCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
VIPSSQVQVIQSLDGGIMQELYVQEGEMVTKGQPLVRIDDTRFRSDYAQQEQEVFGLKTN
CCCCHHHHHHHHHCCHHHHHHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHHHHCCCHH
AIRMRAELDSILISDMTSDWREQVLITKKALVFPENIIAAEPALVKRQQEEYNGRLDNLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCHHHHH
NQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TVNDLQGELNSMRLLRPKVKAAMDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHHHC
GAQDKVSKAIITSPVNGTIKTTHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAF
CCHHHHHHHHEECCCCCCEEEEEEHHHCCHHCCCCCEEEEECCCCCEEEEEECCCHHHHH
LHPGLPAVVKITAYDFTRYGGLKGTVEHISADTSQDEEGNSYYLIRVRTAESSLTKNDGT
HCCCCCCEEEEEEEHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
QMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALREH
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNLTANDLDMVDDVYGAMMTDAPSGHRLIIWALAAMVVCFLLWAGFAKLDKVTTGTGK
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
VIPSSQVQVIQSLDGGIMQELYVQEGEMVTKGQPLVRIDDTRFRSDYAQQEQEVFGLKTN
CCCCHHHHHHHHHCCHHHHHHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHHHHCCCHH
AIRMRAELDSILISDMTSDWREQVLITKKALVFPENIIAAEPALVKRQQEEYNGRLDNLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCHHHHH
NQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TVNDLQGELNSMRLLRPKVKAAMDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHHHC
GAQDKVSKAIITSPVNGTIKTTHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAF
CCHHHHHHHHEECCCCCCEEEEEEHHHCCHHCCCCCEEEEECCCCCEEEEEECCCHHHHH
LHPGLPAVVKITAYDFTRYGGLKGTVEHISADTSQDEEGNSYYLIRVRTAESSLTKNDGT
HCCCCCCEEEEEEEHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
QMPIIPGMLTSVDVITGQRSILEYILNPILRAKDTALREH
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]