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The map label for this gene is ubiA

Identifier: 160877118

GI number: 160877118

Start: 4722914

End: 4723774

Strand: Reverse

Name: ubiA

Synonym: Sbal195_4014

Alternate gene names: 160877118

Gene position: 4723774-4722914 (Counterclockwise)

Preceding gene: 160877119

Following gene: 160877115

Centisome position: 88.34

GC content: 45.18

Gene sequence:

>861_bases
ATGAATTTAAAGCAAAAGTGGGATGTGTATTCCCGTCTTACTCGAATCGACCGCCCCATAGGTACGCTATTATTGCTGTG
GCCATGTTTGATGGCGCTAATGTTAGCTGCGGGTGGTATGCCGGATCTTAAGGTATTGGTTATCTTCATTATTGGCGTAG
TGATCATGCGTGCCTGTGGCTGCATTATTAACGACTATGCCGATCGCGATCTCGATTCTTTTGTTGAACGCACTCGATCA
CGCCCGCTAGCCAGTGGCGAAATCAGCACCAAAGAAGCGCTGATACTGTTCGTCATTTTAGGTTTATCCGCTTTTGGTTT
AGTTTTATTACTCAATGGATTAGTCGTTAAATTATCCGTTGTCGGTATTATCCTCACGATTATTTACCCCTTCACTAAAC
GCATCACCAACATGCCACAGATGTTTTTAGGCATAGTGTGGAGTTGGTCTATCCCTATGGCTTACGCCGCGCAAACGGGT
GAAGTGCCGATGGAGGCTTGGTGGTTATTTGCCGCCAATTGGTGTTGGACTGTCGCCTACGACACTATGTATGCCATGGT
CGATAGGGACGATGATCTAAAAGTGGGTATTAAATCTACTGCGATTTTGTTTGGTAAATATGATCGCCAAATCATAGGCT
TATTTCAGCTTGCCGCGTTGGCTTGTTTTATCGCCGCCGGTTGGAGCGCTGACCGTGGTTTGCTGTATGGTTTAGGCATA
CTGACTTTTGTCGGTTTTAGTACTTACCAGCAAATGCTGATTTTTGATCGTGAACGAGCCCCTTGTTTTAAAGCCTTCCT
CAATAATAACTGGGCAGGTTTAGCCTTATTTGTTGGGCTGGGTGCGGACTATTTGATTTAA

Upstream 100 bases:

>100_bases
CACGCTTTTAGGGGATGAATTCGCATCGGGAGAAGCATGGGTATATGATGCTAAGCCTGAAAACGAGTGGAAACTTGAGG
GTATTGGGAGTACCTAGTTA

Downstream 100 bases:

>100_bases
CGAGTACCGTTTACGCTGGGCAGATCCTGATGGATCATCCACTGATTTTCCGGTGCTAATATTTGTTCTAAATCGATTTG
GTGGATGTTGTCTTGGGAGA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNLKQKWDVYSRLTRIDRPIGTLLLLWPCLMALMLAAGGMPDLKVLVIFIIGVVIMRACGCIINDYADRDLDSFVERTRS
RPLASGEISTKEALILFVILGLSAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRITNMPQMFLGIVWSWSIPMAYAAQTG
EVPMEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALACFIAAGWSADRGLLYGLGI
LTFVGFSTYQQMLIFDRERAPCFKAFLNNNWAGLALFVGLGADYLI

Sequences:

>Translated_286_residues
MNLKQKWDVYSRLTRIDRPIGTLLLLWPCLMALMLAAGGMPDLKVLVIFIIGVVIMRACGCIINDYADRDLDSFVERTRS
RPLASGEISTKEALILFVILGLSAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRITNMPQMFLGIVWSWSIPMAYAAQTG
EVPMEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALACFIAAGWSADRGLLYGLGI
LTFVGFSTYQQMLIFDRERAPCFKAFLNNNWAGLALFVGLGADYLI
>Mature_286_residues
MNLKQKWDVYSRLTRIDRPIGTLLLLWPCLMALMLAAGGMPDLKVLVIFIIGVVIMRACGCIINDYADRDLDSFVERTRS
RPLASGEISTKEALILFVILGLSAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRITNMPQMFLGIVWSWSIPMAYAAQTG
EVPMEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALACFIAAGWSADRGLLYGLGI
LTFVGFSTYQQMLIFDRERAPCFKAFLNNNWAGLALFVGLGADYLI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=278, Percent_Identity=37.0503597122302, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=52.6690391459075, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1786631, Length=162, Percent_Identity=29.0123456790123, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=35, Blast_Score=170, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=34.2657342657343, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=347, Percent_Identity=28.2420749279539, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32565245, Length=145, Percent_Identity=42.0689655172414, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=41.9117647058824, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=294, Percent_Identity=31.6326530612245, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=42.3913043478261, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_SHEB2 (B8E613)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359717.1
- GeneID:   7088852
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3817
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 31955; Mature: 31955

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2217ce68)-; HASH(0x221498ac)-; HASH(0x22458a94)-; HASH(0x224d984c)-; HASH(0x2211d520)-; HASH(0x225d5c38)-; HASH(0x2223370c)-; HASH(0x22233658)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQKWDVYSRLTRIDRPIGTLLLLWPCLMALMLAAGGMPDLKVLVIFIIGVVIMRACG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CIINDYADRDLDSFVERTRSRPLASGEISTKEALILFVILGLSAFGLVLLLNGLVVKLSV
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIILTIIYPFTKRITNMPQMFLGIVWSWSIPMAYAAQTGEVPMEAWWLFAANWCWTVAY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALACFIAAGWSADRGLLYGLGI
HHHHHHHCCCCCCEECHHHHEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LTFVGFSTYQQMLIFDRERAPCFKAFLNNNWAGLALFVGLGADYLI
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCCHHCH
>Mature Secondary Structure
MNLKQKWDVYSRLTRIDRPIGTLLLLWPCLMALMLAAGGMPDLKVLVIFIIGVVIMRACG
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CIINDYADRDLDSFVERTRSRPLASGEISTKEALILFVILGLSAFGLVLLLNGLVVKLSV
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIILTIIYPFTKRITNMPQMFLGIVWSWSIPMAYAAQTGEVPMEAWWLFAANWCWTVAY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
DTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALACFIAAGWSADRGLLYGLGI
HHHHHHHCCCCCCEECHHHHEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LTFVGFSTYQQMLIFDRERAPCFKAFLNNNWAGLALFVGLGADYLI
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCCHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA