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The map label for this gene is tlpA [H]

Identifier: 160877109

GI number: 160877109

Start: 4715796

End: 4716380

Strand: Direct

Name: tlpA [H]

Synonym: Sbal195_4005

Alternate gene names: 160877109

Gene position: 4715796-4716380 (Clockwise)

Preceding gene: 160877108

Following gene: 160877110

Centisome position: 88.19

GC content: 43.76

Gene sequence:

>585_bases
ATGAAACGATATTCTCTGCGACTAATTCTGCTGTGCAGTTTTGTCCTGTTAAACAACGCAGTCCAAGCCCATTCATTGCA
GAATAAGCTTTACGACACTGGCGAAGCGATTCCTAAACCTAGGGTAATGACTGGCTTCGTTGAAATGCAGCATGCACGCG
GCGTACCGGAAGTGCCTTTTATTGATGAAGCGGGGAAAACTCAAACCCTAAAACAACATCAAGGTAAACTGGTTCTCGTT
AATCTTTGGGCGACTTGGTGTGCCCCTTGCCTACGTGAAATCCCAGAACTTCAGCATCTTAAAAAGGATTATCAAGGGAA
AAATATCGCCATTGTCCCAATATCCATCGATGAAGATCCTAAGGATGTGCGACCTTTCCTCACTCAACATAATTTTAGTG
ACTATCAAACTTGGTTCGATCCAACACAAAACATAGAACAGATCATTCCGGCAAACGTCGTTCCTGCGACGTATTTTTTT
GATGCTAAAGGTAATCTTGTTGGTTTCGTACGCGGGTATCTCGATTGGGGCGATAAAGACGTCGCCCCTTATCTTGACCA
ATTGATCGCTAAATACGGCCAATAA

Upstream 100 bases:

>100_bases
GTTTGGCCCATTATTCTTGCTATTACTCGGTGTAGGTCTTTGCCTTGGACTCATTAAACGCGGAGCACTGAGCTCCCCTT
CCTAAAAATAAGGATTCACC

Downstream 100 bases:

>100_bases
TCATTCTGCACTAAGAAAGCCAGTTTAAATCTCCGTTCGGTAGCCCACCCTACATTTGCCGAAACCCGCTGCACCCTAAT
TTGCAGCGGGTATTTTTACA

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKRYSLRLILLCSFVLLNNAVQAHSLQNKLYDTGEAIPKPRVMTGFVEMQHARGVPEVPFIDEAGKTQTLKQHQGKLVLV
NLWATWCAPCLREIPELQHLKKDYQGKNIAIVPISIDEDPKDVRPFLTQHNFSDYQTWFDPTQNIEQIIPANVVPATYFF
DAKGNLVGFVRGYLDWGDKDVAPYLDQLIAKYGQ

Sequences:

>Translated_194_residues
MKRYSLRLILLCSFVLLNNAVQAHSLQNKLYDTGEAIPKPRVMTGFVEMQHARGVPEVPFIDEAGKTQTLKQHQGKLVLV
NLWATWCAPCLREIPELQHLKKDYQGKNIAIVPISIDEDPKDVRPFLTQHNFSDYQTWFDPTQNIEQIIPANVVPATYFF
DAKGNLVGFVRGYLDWGDKDVAPYLDQLIAKYGQ
>Mature_194_residues
MKRYSLRLILLCSFVLLNNAVQAHSLQNKLYDTGEAIPKPRVMTGFVEMQHARGVPEVPFIDEAGKTQTLKQHQGKLVLV
NLWATWCAPCLREIPELQHLKKDYQGKNIAIVPISIDEDPKDVRPFLTQHNFSDYQTWFDPTQNIEQIIPANVVPATYFF
DAKGNLVGFVRGYLDWGDKDVAPYLDQLIAKYGQ

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 22159; Mature: 22159

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYSLRLILLCSFVLLNNAVQAHSLQNKLYDTGEAIPKPRVMTGFVEMQHARGVPEVPF
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCC
IDEAGKTQTLKQHQGKLVLVNLWATWCAPCLREIPELQHLKKDYQGKNIAIVPISIDEDP
CCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCH
KDVRPFLTQHNFSDYQTWFDPTQNIEQIIPANVVPATYFFDAKGNLVGFVRGYLDWGDKD
HHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHCCCCCC
VAPYLDQLIAKYGQ
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKRYSLRLILLCSFVLLNNAVQAHSLQNKLYDTGEAIPKPRVMTGFVEMQHARGVPEVPF
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCC
IDEAGKTQTLKQHQGKLVLVNLWATWCAPCLREIPELQHLKKDYQGKNIAIVPISIDEDP
CCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCH
KDVRPFLTQHNFSDYQTWFDPTQNIEQIIPANVVPATYFFDAKGNLVGFVRGYLDWGDKD
HHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHCCCCCC
VAPYLDQLIAKYGQ
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]