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The map label for this gene is hflK [H]

Identifier: 160876995

GI number: 160876995

Start: 4585012

End: 4586151

Strand: Reverse

Name: hflK [H]

Synonym: Sbal195_3891

Alternate gene names: 160876995

Gene position: 4586151-4585012 (Counterclockwise)

Preceding gene: 160876996

Following gene: 160876994

Centisome position: 85.77

GC content: 47.02

Gene sequence:

>1140_bases
ATGGCTTGGAACGAGCCCGGTAACAAGGGTAATGATCCTTGGGGAAATAAAGGTGGTAACGACAAAGGACCACCGGACCT
TGACGAGGTTTTTCGTAATCTTTCAAAGCGCTTTGGCGGCAAAGGAAACGGCTCAGGCCAATCTTTTAGCTCGTTTAGCC
TAATCATCATTCTTGCTGTTGCTGTAGTTGTTTGGGGACTTTCGGGTTTTTATACAATTAAAGAAGCTGAGCGTGGTGTG
GCACTGCGATTTGGTAAACACGCTGGCGAAATTGGCCCTGGACTTCATTGGAAAGCCACATTTATCGACCAAATTTATCC
CGTCGACATTCAATCGGTTCGCTCTATTCCTGCGTCTGGTAGCATGCTGACATCCGATGAAAACGTCGTGAAAGTTGAGC
TTGATGTTCAGTATCGTATTTTAGATGCTTACTCATATCTATTTAGTGCCGTCGATGCGAACGCCAGCTTGCGTGAAGCG
ACTGACAGTGCACTGCGTTATGTCATTGGACATAACAAGATGGATGATATTCTGACTACCGGCCGTGATGCTATTCGTCG
CGATACGTGGAAAGAGTTAGAGCGCATTCTTGAACCGTACAAATTGGGTCTTGCTGTTGTTGACGTCAACTTCTTACCGG
CGCGTCCGCCTGAAGAAGTGAAAGACGCCTTCGATGACGCGATTTCTGCCCAAGAAGATGAACAACGTTTTATTCGTGAA
GCTGAAGCCTATGCCCGTGAAATTGAACCAAAAGCTCGTGGTGAAGTTGAACGTATGGCACAACAAGCGAATGCTTATAA
AGAGCGTGAAGTCTTAGAAGCTCGCGGTAAAGTGGCTCGTTTTGAGCTGTTATTACCTGAGTACCAAGCCGCGCCTGACG
TGACTCGCAAGCGTTTGTATCTCGATACAATGCAGCAAGTGATGACAGATACGAATAAAGTGCTGATTGATGCCAAGAAC
AACGGCAACTTAATGTACCTACCGCTAGATAAGTTAATTCAGCAGAAGCCTGCGACAACTGAGCTGGAAGCTAAGCCACA
GCAAAATGTCAATTCTTCATCTGTATCAACGACTCGCGCGAATGAGCCTTTGAGTGGACGTCCATCCCGCGATGATCGTA
CTCGCCAAGGGAGGGAGTAA

Upstream 100 bases:

>100_bases
ACAGAGTCAGGGTGAGTTAGAAACCTTCATCTACGAAGATTCGATAGATGAGGCTGTTTGTTAATAATCTAATTTATTTC
ATCCACTTATGGAGTGCTAA

Downstream 100 bases:

>100_bases
TCCATGGGTAGATTAAGCGTTATTCTTATCGCCGTACTCTTAGGTATTGGTTTGTCATCTTTAATGGTGGTGAATGAAGG
CGAACGCGCAATTGTGGCGC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGQSFSSFSLIIILAVAVVVWGLSGFYTIKEAERGV
ALRFGKHAGEIGPGLHWKATFIDQIYPVDIQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREA
TDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERILEPYKLGLAVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
AEAYAREIEPKARGEVERMAQQANAYKEREVLEARGKVARFELLLPEYQAAPDVTRKRLYLDTMQQVMTDTNKVLIDAKN
NGNLMYLPLDKLIQQKPATTELEAKPQQNVNSSSVSTTRANEPLSGRPSRDDRTRQGRE

Sequences:

>Translated_379_residues
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGQSFSSFSLIIILAVAVVVWGLSGFYTIKEAERGV
ALRFGKHAGEIGPGLHWKATFIDQIYPVDIQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREA
TDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERILEPYKLGLAVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
AEAYAREIEPKARGEVERMAQQANAYKEREVLEARGKVARFELLLPEYQAAPDVTRKRLYLDTMQQVMTDTNKVLIDAKN
NGNLMYLPLDKLIQQKPATTELEAKPQQNVNSSSVSTTRANEPLSGRPSRDDRTRQGRE
>Mature_378_residues
AWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGQSFSSFSLIIILAVAVVVWGLSGFYTIKEAERGVA
LRFGKHAGEIGPGLHWKATFIDQIYPVDIQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREAT
DSALRYVIGHNKMDDILTTGRDAIRRDTWKELERILEPYKLGLAVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIREA
EAYAREIEPKARGEVERMAQQANAYKEREVLEARGKVARFELLLPEYQAAPDVTRKRLYLDTMQQVMTDTNKVLIDAKNN
GNLMYLPLDKLIQQKPATTELEAKPQQNVNSSSVSTTRANEPLSGRPSRDDRTRQGRE

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=361, Percent_Identity=53.185595567867, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1786697, Length=284, Percent_Identity=22.5352112676056, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 42394; Mature: 42263

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGQSFSSFSLIIILAV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AVVVWGLSGFYTIKEAERGVALRFGKHAGEIGPGLHWKATFIDQIYPVDIQSVRSIPASG
HHHHHCCCCCEEEHHHCCCEEEEECCCCCCCCCCCCEEHHHHHCCCCCCHHHHHCCCCCC
SMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREATDSALRYVIGHNKMDDILTT
CEEECCCCEEEEEECCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHC
GRDAIRRDTWKELERILEPYKLGLAVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
CHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
AEAYAREIEPKARGEVERMAQQANAYKEREVLEARGKVARFELLLPEYQAAPDVTRKRLY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHCCCHHHHHHHH
LDTMQQVMTDTNKVLIDAKNNGNLMYLPLDKLIQQKPATTELEAKPQQNVNSSSVSTTRA
HHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
NEPLSGRPSRDDRTRQGRE
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGQSFSSFSLIIILAV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AVVVWGLSGFYTIKEAERGVALRFGKHAGEIGPGLHWKATFIDQIYPVDIQSVRSIPASG
HHHHHCCCCCEEEHHHCCCEEEEECCCCCCCCCCCCEEHHHHHCCCCCCHHHHHCCCCCC
SMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREATDSALRYVIGHNKMDDILTT
CEEECCCCEEEEEECCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHC
GRDAIRRDTWKELERILEPYKLGLAVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
CHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
AEAYAREIEPKARGEVERMAQQANAYKEREVLEARGKVARFELLLPEYQAAPDVTRKRLY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHCCCHHHHHHHH
LDTMQQVMTDTNKVLIDAKNNGNLMYLPLDKLIQQKPATTELEAKPQQNVNSSSVSTTRA
HHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
NEPLSGRPSRDDRTRQGRE
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]