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The map label for this gene is gltP [H]

Identifier: 160876957

GI number: 160876957

Start: 4536242

End: 4537486

Strand: Reverse

Name: gltP [H]

Synonym: Sbal195_3853

Alternate gene names: 160876957

Gene position: 4537486-4536242 (Counterclockwise)

Preceding gene: 160876958

Following gene: 160876954

Centisome position: 84.86

GC content: 49.96

Gene sequence:

>1245_bases
ATGATTAAATCACTTTCGACGCGGATCTTTATAGGTCTGTTTGCGGGTCTTATTTTCGGCACAATAGTGCAGTACTTCTT
AAACGATATCGGTTTCTTCTCGGACAATTTGGTCGAGCTTGCCGGCGGCGTTGGCACTATGTTCGTCAATATGATCATGA
TGCTAGTCGTGCCATTAGTGTTTGTGAGTATTGTTTGTGGTGTCTGTGAGCTGCAAGATCTCAAAAGTTTTGGCCGTTTA
GGCGGTAAGACCTTCGGTTTCTATATCATCAATACCTTTGTCGCGATCGCGACGGCATTATTAGTCGTGCTGTTACTCGA
CCCAGGTAAAGGTGTCGATATGAGCAGCACAGACGGCCTGGCCATTACTGCAACTGAGCTGCCAAGTCTGATGGCACTGG
TGATCGACATAGTCCCGCGTAACCCTGTGGCGGCGTTTATGTCGGGCAATATGTTGCAAGTGATCTTTATGGCCCTAATG
CTTGGCGGCGTGATTAAGTCACTCGGTGAGCATGTCGCTGGCGCTGTGCAAGGTTTTCAAACCGCGAATAAAATCATGAT
GAAGCTGATTTCTGTGGTGATGAGCCTAGCGCCCTACGGTGTGTTTGCCTTGATGTTCAAGCTCGGCGCGACCTTAGATG
CTGGCGTGTTTATGAGCGTAGTTGAGTACATGGTGCTGATCCTCGCGCTGCTACTACTGTGGATTTTTGTGGTTTACCCA
ATGGCGGTGGGCATATTTACCCCAATTTCGGCCAAAACCTTCCGCGAGAAGACCCAAGAGCAAGTGTTGTTTTCACTGTC
GACCGCAAGCTCGAATGCGACGATTCCTGTGACTATGCGTACCTTAACCGAAAAGTTAGGTGTGAATCGCGCGGTAGCTG
GCTTTGGTGTGCCGCTCGGCGCGACCATGAACATGGGCGGCGTGGCGATTTACATCACGATCGCGATTTTCTTTGTCGCT
AACGCCTTTGGCATGCCTATCACCTCTGATCAATTGCCTTCGCTGTTATTTAGCATCTTCCTGCTCTCTGTCGGCGCAGG
TGGCGTGCCCGGCGGCGGCATGGTGATGATAGGCGTGTTAATCCATCAAATGGGTTTACCGATAGAAGCCTTCGCCATAG
TTGCGGCGTTAGATCGCATTATCGATATGGTGCTGACCTCTTGTAACGTGGTAGGTGATGCTGCGGTATTGACCATAGTG
GACCAAACCGAGAAAGTGCATCAGGTTGAACTAGCGAAGAGCTAA

Upstream 100 bases:

>100_bases
TGTTTCACTATCCCCTGCCTAAGCCAAAAATGGATTGGCAATTGTGCTCATCATGGAAGATGAATAACAAAAAAACTACA
TTTCTGGGGAAACCACAAGC

Downstream 100 bases:

>100_bases
TCTGGACGTTAAGTCATATGCTATAAATGCAAAAAGCCACTGTCATCAGTGGCTTTTTTGTTCATATTGATCTATTTAAT
GCTGGCTGAGGAGCCTACTG

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIKSLSTRIFIGLFAGLIFGTIVQYFLNDIGFFSDNLVELAGGVGTMFVNMIMMLVVPLVFVSIVCGVCELQDLKSFGRL
GGKTFGFYIINTFVAIATALLVVLLLDPGKGVDMSSTDGLAITATELPSLMALVIDIVPRNPVAAFMSGNMLQVIFMALM
LGGVIKSLGEHVAGAVQGFQTANKIMMKLISVVMSLAPYGVFALMFKLGATLDAGVFMSVVEYMVLILALLLLWIFVVYP
MAVGIFTPISAKTFREKTQEQVLFSLSTASSNATIPVTMRTLTEKLGVNRAVAGFGVPLGATMNMGGVAIYITIAIFFVA
NAFGMPITSDQLPSLLFSIFLLSVGAGGVPGGGMVMIGVLIHQMGLPIEAFAIVAALDRIIDMVLTSCNVVGDAAVLTIV
DQTEKVHQVELAKS

Sequences:

>Translated_414_residues
MIKSLSTRIFIGLFAGLIFGTIVQYFLNDIGFFSDNLVELAGGVGTMFVNMIMMLVVPLVFVSIVCGVCELQDLKSFGRL
GGKTFGFYIINTFVAIATALLVVLLLDPGKGVDMSSTDGLAITATELPSLMALVIDIVPRNPVAAFMSGNMLQVIFMALM
LGGVIKSLGEHVAGAVQGFQTANKIMMKLISVVMSLAPYGVFALMFKLGATLDAGVFMSVVEYMVLILALLLLWIFVVYP
MAVGIFTPISAKTFREKTQEQVLFSLSTASSNATIPVTMRTLTEKLGVNRAVAGFGVPLGATMNMGGVAIYITIAIFFVA
NAFGMPITSDQLPSLLFSIFLLSVGAGGVPGGGMVMIGVLIHQMGLPIEAFAIVAALDRIIDMVLTSCNVVGDAAVLTIV
DQTEKVHQVELAKS
>Mature_414_residues
MIKSLSTRIFIGLFAGLIFGTIVQYFLNDIGFFSDNLVELAGGVGTMFVNMIMMLVVPLVFVSIVCGVCELQDLKSFGRL
GGKTFGFYIINTFVAIATALLVVLLLDPGKGVDMSSTDGLAITATELPSLMALVIDIVPRNPVAAFMSGNMLQVIFMALM
LGGVIKSLGEHVAGAVQGFQTANKIMMKLISVVMSLAPYGVFALMFKLGATLDAGVFMSVVEYMVLILALLLLWIFVVYP
MAVGIFTPISAKTFREKTQEQVLFSLSTASSNATIPVTMRTLTEKLGVNRAVAGFGVPLGATMNMGGVAIYITIAIFFVA
NAFGMPITSDQLPSLLFSIFLLSVGAGGVPGGGMVMIGVLIHQMGLPIEAFAIVAALDRIIDMVLTSCNVVGDAAVLTIV
DQTEKVHQVELAKS

Specific function: This carrier protein is part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI21314632, Length=421, Percent_Identity=28.2660332541568, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI40254478, Length=473, Percent_Identity=26.6384778012685, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI169790839, Length=421, Percent_Identity=25.41567695962, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI194239697, Length=417, Percent_Identity=24.9400479616307, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI66773030, Length=265, Percent_Identity=30.5660377358491, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI5032093, Length=387, Percent_Identity=26.8733850129199, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4827012, Length=239, Percent_Identity=30.5439330543933, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI223468566, Length=271, Percent_Identity=28.0442804428044, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI223468564, Length=262, Percent_Identity=27.8625954198473, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI262359914, Length=365, Percent_Identity=26.027397260274, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI301601644, Length=147, Percent_Identity=36.0544217687075, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790514, Length=427, Percent_Identity=28.8056206088993, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789947, Length=413, Percent_Identity=26.1501210653753, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788024, Length=439, Percent_Identity=28.4738041002278, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789473, Length=402, Percent_Identity=28.6069651741293, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71983106, Length=400, Percent_Identity=28.75, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71983099, Length=400, Percent_Identity=28.75, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17537407, Length=416, Percent_Identity=27.4038461538462, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193206654, Length=425, Percent_Identity=27.0588235294118, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI193206505, Length=442, Percent_Identity=24.8868778280543, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71996953, Length=420, Percent_Identity=26.1904761904762, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17541374, Length=403, Percent_Identity=24.8138957816377, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583025, Length=433, Percent_Identity=25.1732101616628, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17137668, Length=433, Percent_Identity=25.1732101616628, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583023, Length=433, Percent_Identity=25.1732101616628, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281360481, Length=449, Percent_Identity=23.3853006681514, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360483, Length=450, Percent_Identity=23.3333333333333, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17137666, Length=450, Percent_Identity=23.3333333333333, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43858; Mature: 43858

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKSLSTRIFIGLFAGLIFGTIVQYFLNDIGFFSDNLVELAGGVGTMFVNMIMMLVVPLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
FVSIVCGVCELQDLKSFGRLGGKTFGFYIINTFVAIATALLVVLLLDPGKGVDMSSTDGL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
AITATELPSLMALVIDIVPRNPVAAFMSGNMLQVIFMALMLGGVIKSLGEHVAGAVQGFQ
EEEHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TANKIMMKLISVVMSLAPYGVFALMFKLGATLDAGVFMSVVEYMVLILALLLLWIFVVYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAVGIFTPISAKTFREKTQEQVLFSLSTASSNATIPVTMRTLTEKLGVNRAVAGFGVPLG
HHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHCCCHHHHHCCCCCC
ATMNMGGVAIYITIAIFFVANAFGMPITSDQLPSLLFSIFLLSVGAGGVPGGGMVMIGVL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IHQMGLPIEAFAIVAALDRIIDMVLTSCNVVGDAAVLTIVDQTEKVHQVELAKS
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971622; 1551855; 8265357; 9278503 [H]