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The map label for this gene is ywrD [H]

Identifier: 160876918

GI number: 160876918

Start: 4494140

End: 4495852

Strand: Reverse

Name: ywrD [H]

Synonym: Sbal195_3814

Alternate gene names: 160876918

Gene position: 4495852-4494140 (Counterclockwise)

Preceding gene: 160876919

Following gene: 160876917

Centisome position: 84.08

GC content: 48.74

Gene sequence:

>1713_bases
ATGATAAAAACAATAAAATCAATTTGTACCTTAGTGACAGTGGCGACGGCAATATCGTCTTCAGGAGTGATGGCCATGGA
TAGGATCACGGGTAAAGCCTTTGCGACGCGCTCAGAAGTGTATGCCACCCATGGAATGGCGGCGACCAGTCAACCACTCG
CCACACAAGTCGCTATTGATATACTCAAGCAGGGCGGTAGTGCGGTCGATGCGGCGATTGCCGCGAATGCCATGCTAGGG
TTAGTCGAACCAACGGGTTCGGGTGTTGGTGGTGACTTATTTGCCATCGTCTGGAGCGCGAAAGATAAACGCCTCTATGG
TCTTAACGCTTCGGGCCGCAGTCCAAAATCCTTAAGTTTAGAAAAGCTTAAATCTCTCGGCTTAGACTATTTACCGCCGC
TTGGACCCTTGCCTGTTTCTGTGCCCGGCGCTGTGGATGGCTGGTATGAACTGCATAATAAGTTCGGCAAATTAGCGATG
GCCGATAATCTTGCGCCCGCAATCCATTACGCCCGTGATGGTTTCCCTGTGTCCGAACTCATCGCCTATTACCTTGAGGG
GAGTGGTAAAAAACTCGCTAAATTCCCCGGTTTTAAAGAAACCTATATGCCTAATGGCAAGATGCCAGCGGTGGGCGAAA
TCTTTAAAAACCCAGCGCTTGCTAATACCTATGAGAAAATTGCCAAGGGTGGCCGCGATGCTTTCTATAAAGGCGATATC
GCCAAAAGTATCGATAAGTACATGAAATCCCAAGGTGGTTATTTAAGTTATGATGACTTAGCGAGCCATACTAGCGAATG
GATAGATCCGGTTTCGGTGAACTACCGTGGTTACGATGTATGGGAACTGCCGCCCAATGGTCAAGGCATTGCGGCGCTAC
AAATCTTAAAAACCATGGAACCCTTTAATGTGGCTGCTATGGGCTTTAATAGCCCCGAATATGTGCATTTATTTGTTGAA
GCCAAAAAACTCGCCTTTGCCGACAGAGCTAAGTTTTATGCCGACATGGCCTTTAATAAAGTGCCGGTTAACGATTTGAT
TTCGCAGCAATACAATTATGATCGCGCTAAGTTAATCGATCCCAATAAAGCGGCCAAGAGTGTTGATGCGGGTAATCCTG
CGTTACAACATGGCGATACTGTATACCTGACCACCGCCGACAAAGACGGCAACATGGTGTCACTCATTCAAAGTAACTAC
CGTGGTATGGGTTCAGGAATGACGCCGCCGGATCTCGGTTTTGTGCTGCAAGACCGTGGGCAAATGTTTGATTTAACTGA
GGGGCGTTTTAATACCTACGCACCGGGCAAGCGTCCATTTCATACCATCATTCCCGCTTTTGTGACCAAAGACGGTAAAC
CTTGGCTCAGCTTTGGGGTGATGGGCGGCGCGACTCAACCACAGATGCACGCGCAGATTCTAATGAACCTGATTGATTTT
AAAATGAACTTGCAAGAAGCGGGCGATGCCCCCAGAATTTTGCATATGGGTTCAACTGAGCCCACCGGCGAAGTGATGAA
TGACGGCGGCTACGTCAGTCTGGAATCGGGCTTCCCTGTGGAAACGCGCCGTGAGCTTATCAAGAAAGGTCATGTGCTGC
GTGATGGACTTGGGGATTTTGGCGGCTATCAAGCTATTGGATTTAATGCTGAAACGGGCGTGTATCGTGGCGCTTCTGAG
AGCCGTAAAGATGGTCATGCCGCCGGTTATTAA

Upstream 100 bases:

>100_bases
ACGACATTTTTGCTTACGTTTAACTTAGGCCTATGCGGTATTGGTTGGTGATATTTTCGACCATCCTTGTTACCTTAATT
TCTCCAGAGTGGGAGGAATT

Downstream 100 bases:

>100_bases
CTTCAGCGTCACGCTAAGGTAAGCTTGAGGTAGAGTAAGCTTTGCTGCTCTAATTCGATTAAACTGAATGACGAGACTTT
CCAGTCTCGTCATTTTTACA

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAIDILKQGGSAVDAAIAANAMLG
LVEPTGSGVGGDLFAIVWSAKDKRLYGLNASGRSPKSLSLEKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAM
ADNLAPAIHYARDGFPVSELIAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
AKSIDKYMKSQGGYLSYDDLASHTSEWIDPVSVNYRGYDVWELPPNGQGIAALQILKTMEPFNVAAMGFNSPEYVHLFVE
AKKLAFADRAKFYADMAFNKVPVNDLISQQYNYDRAKLIDPNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNY
RGMGSGMTPPDLGFVLQDRGQMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQILMNLIDF
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDFGGYQAIGFNAETGVYRGASE
SRKDGHAAGY

Sequences:

>Translated_570_residues
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAIDILKQGGSAVDAAIAANAMLG
LVEPTGSGVGGDLFAIVWSAKDKRLYGLNASGRSPKSLSLEKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAM
ADNLAPAIHYARDGFPVSELIAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
AKSIDKYMKSQGGYLSYDDLASHTSEWIDPVSVNYRGYDVWELPPNGQGIAALQILKTMEPFNVAAMGFNSPEYVHLFVE
AKKLAFADRAKFYADMAFNKVPVNDLISQQYNYDRAKLIDPNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNY
RGMGSGMTPPDLGFVLQDRGQMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQILMNLIDF
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDFGGYQAIGFNAETGVYRGASE
SRKDGHAAGY
>Mature_570_residues
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAIDILKQGGSAVDAAIAANAMLG
LVEPTGSGVGGDLFAIVWSAKDKRLYGLNASGRSPKSLSLEKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAM
ADNLAPAIHYARDGFPVSELIAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
AKSIDKYMKSQGGYLSYDDLASHTSEWIDPVSVNYRGYDVWELPPNGQGIAALQILKTMEPFNVAAMGFNSPEYVHLFVE
AKKLAFADRAKFYADMAFNKVPVNDLISQQYNYDRAKLIDPNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNY
RGMGSGMTPPDLGFVLQDRGQMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQILMNLIDF
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDFGGYQAIGFNAETGVYRGASE
SRKDGHAAGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=558, Percent_Identity=27.5985663082437, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI73915090, Length=558, Percent_Identity=27.5985663082437, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI73915096, Length=558, Percent_Identity=27.5985663082437, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI73915094, Length=558, Percent_Identity=27.5985663082437, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI113429324, Length=554, Percent_Identity=25.9927797833935, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI113429326, Length=559, Percent_Identity=25.9391771019678, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI109148539, Length=469, Percent_Identity=26.6524520255864, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI153266885, Length=550, Percent_Identity=24.9090909090909, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI153266901, Length=551, Percent_Identity=24.8638838475499, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI153266907, Length=550, Percent_Identity=23.8181818181818, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1789856, Length=566, Percent_Identity=31.8021201413428, Blast_Score=231, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI193208247, Length=520, Percent_Identity=26.7307692307692, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193208245, Length=520, Percent_Identity=26.7307692307692, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17542894, Length=498, Percent_Identity=26.3052208835341, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI212646519, Length=535, Percent_Identity=25.981308411215, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI72000294, Length=535, Percent_Identity=25.981308411215, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17506189, Length=530, Percent_Identity=24.9056603773585, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45551474, Length=551, Percent_Identity=27.5862068965517, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161077880, Length=551, Percent_Identity=27.5862068965517, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24642670, Length=551, Percent_Identity=27.5862068965517, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24642666, Length=551, Percent_Identity=27.5862068965517, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161077878, Length=551, Percent_Identity=27.5862068965517, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI18859893, Length=461, Percent_Identity=25.8134490238612, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161077496, Length=555, Percent_Identity=24.8648648648649, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859741, Length=469, Percent_Identity=24.0938166311301, Blast_Score=124, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 61506; Mature: 61506

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAID
CCHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ILKQGGSAVDAAIAANAMLGLVEPTGSGVGGDLFAIVWSAKDKRLYGLNASGRSPKSLSL
HHHCCCCHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCH
EKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAMADNLAPAIHYARDGFPVSEL
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCCHHHH
IAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
HHHHHCCCCCHHHHCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEECCHH
AKSIDKYMKSQGGYLSYDDLASHTSEWIDPVSVNYRGYDVWELPPNGQGIAALQILKTME
HHHHHHHHHCCCCEECHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHCC
PFNVAAMGFNSPEYVHLFVEAKKLAFADRAKFYADMAFNKVPVNDLISQQYNYDRAKLID
CCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEC
PNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNYRGMGSGMTPPDLGFVLQDRG
CCHHHHCCCCCCCCHHCCCEEEEEECCCCCCEEHEEHHCCCCCCCCCCCCCCCHHCCCCC
QMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQILMNLIDF
CEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDF
HHCHHHCCCCCEEEECCCCCCCCHHCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCCCC
GGYQAIGFNAETGVYRGASESRKDGHAAGY
CCCEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAID
CCHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ILKQGGSAVDAAIAANAMLGLVEPTGSGVGGDLFAIVWSAKDKRLYGLNASGRSPKSLSL
HHHCCCCHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCH
EKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAMADNLAPAIHYARDGFPVSEL
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCCHHHH
IAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
HHHHHCCCCCHHHHCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEECCHH
AKSIDKYMKSQGGYLSYDDLASHTSEWIDPVSVNYRGYDVWELPPNGQGIAALQILKTME
HHHHHHHHHCCCCEECHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHCC
PFNVAAMGFNSPEYVHLFVEAKKLAFADRAKFYADMAFNKVPVNDLISQQYNYDRAKLID
CCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEC
PNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNYRGMGSGMTPPDLGFVLQDRG
CCHHHHCCCCCCCCHHCCCEEEEEECCCCCCEEHEEHHCCCCCCCCCCCCCCCHHCCCCC
QMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQILMNLIDF
CEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDF
HHCHHHCCCCCEEEECCCCCCCCHHCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCCCC
GGYQAIGFNAETGVYRGASESRKDGHAAGY
CCCEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]