Click here to switch to the map view.

The map label for this gene is gcvT [H]

Identifier: 160876905

GI number: 160876905

Start: 4481688

End: 4482782

Strand: Reverse

Name: gcvT [H]

Synonym: Sbal195_3801

Alternate gene names: 160876905

Gene position: 4482782-4481688 (Counterclockwise)

Preceding gene: 160876906

Following gene: 160876904

Centisome position: 83.83

GC content: 50.41

Gene sequence:

>1095_bases
ATGGCTAACAAAACTATTCTGTTTAACAAGCACTTAGAATCAAACGCTAAGATGGTCGACTTCCACGGTTGGGACATGCC
TCTCAACTATGGTTCACAAATCGAAGAACACAATGCCGTGCGTCAAGACGCGGGTATGTTCGACGTTTCCCACATGACTG
TGGTTGATGTGATTGGTAACGACGCTTGTGCATTTCTGCGTAAGTTGCTGGCAAACGATGTGGCTAAGCTTAAAGTTCCA
GGTAAAGCCTTATACGGCGGCATGTTAGACGAAAATGCTGGCGTCATCGACGACCTCATCACTTACTACCTCACTGACAC
TAATTACCGCGTGGTAGTGAACTCAGCGACCCGCGAAAAAGATCTCGCTTGGATCGCCAAGCAATCCCAAGGTTTTGATG
TCACTGTGACTGAGCGTCCTGAGCTGGCGATGATCGCCGTTCAAGGTCCAAACGCTAAAGCGAAAGCCGCTGCCGTGCTC
AGTGCCGAGCAAAACGCCGCCATCGAAGGCATGAAACCTTTCTTCGGTAAGCAAGCCGGTTCTCTGTTTATTGCGACAAC
GGGTTACACAGGCGAAGCGGGCTATGAAATTATCGTCCCAGAAGATGAAGCCCAAGCCATGTGGCAAGCATTGTTAGATC
AAGGTGTTAAACCTTGTGGTCTCGGTGCCCGTGACACACTGCGTCTCGAAGCCGGTATGAATCTCTACGGCTTAGACATG
GACGAAACCATCAACCCATTGGCCGCCAACATGGGCTGGACCATCGCATGGGAACCGAGCGACCGTGACTTCATCGGCCG
TAAAGCCCTCGAAACACTTCGCGATGCCGGAACCGACAAACTTGTTGGTCTAGTGATGGAAGAAAAGGGCGTGTTACGCC
ATGATATGCCAGTATTTTTCACCGACTCAGCCGGTGTTGAGCACCAAGGCGTGATTACCAGCGGTACTTTCTCGCCAACA
TTGGGCTATTCTATTGCGATGGCGCGTGTTCCTAACTCGATTGGGGATACGGCGGAAGTCGAAATGCGTAAAAAACGTGT
GGCTGTTAGAGTAGTAGCGCCAAACTTTGTGCGCAACGGTAAACAAGCATTTTAA

Upstream 100 bases:

>100_bases
AATTTGTGACGCAAGGTATAATTTCGCCGCATTTTAGACCCTAGTATCTACACCCTACACTAGGCAGAGACCTGAAAAAG
GCCGCAAAAAAGGGATAACA

Downstream 100 bases:

>100_bases
AAAAACGGAACAAGGAACAAGAACAATGAGCAATATTCCGACAGAACTGAAATACGCCTCTTCACACGAATGGATCCGCA
AGGAAGAAGACGGCAGCTAC

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVP
GKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVL
SAEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPEDEAQAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPT
LGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF

Sequences:

>Translated_364_residues
MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVP
GKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVL
SAEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPEDEAQAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPT
LGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF
>Mature_363_residues
ANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVPG
KALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLS
AEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPEDEAQAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDMD
ETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPTL
GYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=373, Percent_Identity=34.3163538873995, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI257796258, Length=344, Percent_Identity=34.8837209302326, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI257796254, Length=357, Percent_Identity=31.3725490196078, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI257796256, Length=307, Percent_Identity=33.5504885993485, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI24797151, Length=385, Percent_Identity=24.4155844155844, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI197927446, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI21361378, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789272, Length=361, Percent_Identity=67.8670360110803, Blast_Score=520, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17560118, Length=378, Percent_Identity=34.1269841269841, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71994045, Length=347, Percent_Identity=25.3602305475504, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994052, Length=347, Percent_Identity=25.3602305475504, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320222, Length=343, Percent_Identity=34.9854227405248, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI20129441, Length=377, Percent_Identity=33.1564986737401, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI28571104, Length=262, Percent_Identity=24.4274809160305, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 39657; Mature: 39526

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGN
CCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCC
DACAFLRKLLANDVAKLKVPGKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREK
HHHHHHHHHHHCCHHEEECCCHHHCCCCCCCCCCHHHHHHHHEEECCCEEEEEECCCCCC
DLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLSAEQNAAIEGMKPFFGKQAG
HHHEEEECCCCCEEEEECCCCEEEEEEECCCCCCHHEEEEECCCCCCCCCCCCCCCCCCC
SLFIATTGYTGEAGYEIIVPEDEAQAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
CEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCH
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFF
HHHCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCHHCCCCEEE
TDSAGVEHQGVITSGTFSPTLGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNG
ECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCEEEEEEECCHHHCCC
KQAF
CCCC
>Mature Secondary Structure 
ANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGN
CCCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCC
DACAFLRKLLANDVAKLKVPGKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREK
HHHHHHHHHHHCCHHEEECCCHHHCCCCCCCCCCHHHHHHHHEEECCCEEEEEECCCCCC
DLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLSAEQNAAIEGMKPFFGKQAG
HHHEEEECCCCCEEEEECCCCEEEEEEECCCCCCHHEEEEECCCCCCCCCCCCCCCCCCC
SLFIATTGYTGEAGYEIIVPEDEAQAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
CEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCH
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFF
HHHCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHEEEEECCCCCHHCCCCEEE
TDSAGVEHQGVITSGTFSPTLGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNG
ECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCEEEEEEECCHHHCCC
KQAF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA