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The map label for this gene is rstB [H]

Identifier: 160876794

GI number: 160876794

Start: 4352355

End: 4353647

Strand: Reverse

Name: rstB [H]

Synonym: Sbal195_3689

Alternate gene names: 160876794

Gene position: 4353647-4352355 (Counterclockwise)

Preceding gene: 160876795

Following gene: 160876790

Centisome position: 81.42

GC content: 48.72

Gene sequence:

>1293_bases
ATGAAGAAGTTGATGACTTCACTGGTGCTGGTGGTGCTGGTGGCCATTGCGAGCCTAGGCTGGTCGATAAGTGAGTTTGC
CAGTCTGCTAGATCCTGATAATGACACGCAAACCCCAGCCACTCATCTTGCGGCATTAAAACTGTTGGGCGGCACACTGG
CGCAAACGCTCGATAACGATAGCGTTAACAATCACAGTTTTATCGCAAACTGGAACCAGCTAAATTCAGAGCAATTGTCT
TTAGCGAGTGAAGCCGATTTCGTCTTACCCTCAGCCCTAAAAACCGCGTTTTATGCGGGAGAATCGCTGCTGCTGGAGTC
CGATGACGGTATCTCCTTGCATTATTTACTGCCGAAAACGGGGCAGGTATTGAACATCAATACCGATATTGTCACGCCCA
CCGATGGCAACTTTGACTTGAATAAGCTGTATACCATGCTTTTTTATGGTGGTGTGGTGCTGATATTGTTGGTGTGGGTG
TCGCCCTTGATCCGTCAGCTGGTTAATCTCAGTAAGGCGACCCAAGCGTTTGGCATGGGGGAGTTGCAGCAGAGAATTCC
TGTTAGAAAAATGTCTTACATAGGCACTATTGAAAGCGAATTCAACCGCATGGCGGATCGTATTCAGCAATTGATCGATG
ACAATAAACTGCTCAGTCGGGCTGTTTCTCATGATTTAAAAACTCCGATCGCACGGTTAAGATTCGGCATTGAGGCGCTG
GAAGAAACCCAAAGCGAACAGCTCAGAGTGAAGTATTTCCAGCGCTTGAACCGCGATCTAGACACGATGGAAGACTTGGT
GATGACGCTGCTGAGTTATGCCCGCCTCGATGAAGCGAATATCCAGCCCGATTGGCAGTCGATTGAACTCAATGCTTGGC
TACTCGAAAAGTATCAAGGCCAAGTGTACCCCGATTTTTCAGTTGAACTGGTTTCCTATCCCACAGCACTCAAGATCAAG
ACAGACCCTAAGTACTTATCAATGCAGGTGAATAATTTGCTCAATAATGCGCTGCGTTTTGGTAAGGCAAAGATTCGGCT
GACGTTGGCAGTCGAGGAGGGCGCGACCTGGTTACACGTTGACGATGACGGTCCAGGCATAGACGAACTGGAGTCTGCGC
AGGTGATTAAGCCTTTTGTGCGTGGTCAGCACAGCCGTGGAAATTCCGGTCATGGCATGGGATTGGCGATTGTCGACAGA
ATTGGTTGTTGGATGAATGCCCCATTACGTATTGGACGCTCCCCTGAGCTCGGTGGCGCTCGCATGTCACTAAAATTCAA
GGCTGAAGTTTAA

Upstream 100 bases:

>100_bases
TACGCAAAAAATTGCAGGAAGCGTTAAGCCAGCCCTATAAAGTGAAAACCATCCGTGGCAAGGGATACCTGTTTTGCCGC
GACGAAGGTGAGCAAGCTTT

Downstream 100 bases:

>100_bases
CGCTGGAGTTTAAGGCTGAAGTTTAGGGTTGGAGATTTAGATCGGAATTTAAGGCTGAATTTTAAAGCGGAGTTTAAGGC
AAGAGTTTAAGGCAAGAGTT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKKLMTSLVLVVLVAIASLGWSISEFASLLDPDNDTQTPATHLAALKLLGGTLAQTLDNDSVNNHSFIANWNQLNSEQLS
LASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKTGQVLNINTDIVTPTDGNFDLNKLYTMLFYGGVVLILLVWV
SPLIRQLVNLSKATQAFGMGELQQRIPVRKMSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTALKIK
TDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHVDDDGPGIDELESAQVIKPFVRGQHSRGNSGHGMGLAIVDR
IGCWMNAPLRIGRSPELGGARMSLKFKAEV

Sequences:

>Translated_430_residues
MKKLMTSLVLVVLVAIASLGWSISEFASLLDPDNDTQTPATHLAALKLLGGTLAQTLDNDSVNNHSFIANWNQLNSEQLS
LASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKTGQVLNINTDIVTPTDGNFDLNKLYTMLFYGGVVLILLVWV
SPLIRQLVNLSKATQAFGMGELQQRIPVRKMSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTALKIK
TDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHVDDDGPGIDELESAQVIKPFVRGQHSRGNSGHGMGLAIVDR
IGCWMNAPLRIGRSPELGGARMSLKFKAEV
>Mature_430_residues
MKKLMTSLVLVVLVAIASLGWSISEFASLLDPDNDTQTPATHLAALKLLGGTLAQTLDNDSVNNHSFIANWNQLNSEQLS
LASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKTGQVLNINTDIVTPTDGNFDLNKLYTMLFYGGVVLILLVWV
SPLIRQLVNLSKATQAFGMGELQQRIPVRKMSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTALKIK
TDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHVDDDGPGIDELESAQVIKPFVRGQHSRGNSGHGMGLAIVDR
IGCWMNAPLRIGRSPELGGARMSLKFKAEV

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=276, Percent_Identity=35.1449275362319, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789808, Length=255, Percent_Identity=32.156862745098, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790551, Length=250, Percent_Identity=27.2, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=23.2727272727273, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=100, Percent_Identity=36, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788279, Length=277, Percent_Identity=24.9097472924188, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=24.0343347639485, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47935; Mature: 47935

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLMTSLVLVVLVAIASLGWSISEFASLLDPDNDTQTPATHLAALKLLGGTLAQTLDND
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SVNNHSFIANWNQLNSEQLSLASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKT
CCCCCCEEEEHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCC
GQVLNINTDIVTPTDGNFDLNKLYTMLFYGGVVLILLVWVSPLIRQLVNLSKATQAFGMG
CCEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ELQQRIPVRKMSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHCC
QVYPDFSVELVSYPTALKIKTDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHV
CCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEEEE
DDDGPGIDELESAQVIKPFVRGQHSRGNSGHGMGLAIVDRIGCWMNAPLRIGRSPELGGA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCC
RMSLKFKAEV
EEEEEEEECC
>Mature Secondary Structure
MKKLMTSLVLVVLVAIASLGWSISEFASLLDPDNDTQTPATHLAALKLLGGTLAQTLDND
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SVNNHSFIANWNQLNSEQLSLASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKT
CCCCCCEEEEHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCC
GQVLNINTDIVTPTDGNFDLNKLYTMLFYGGVVLILLVWVSPLIRQLVNLSKATQAFGMG
CCEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ELQQRIPVRKMSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHCC
QVYPDFSVELVSYPTALKIKTDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHV
CCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCEEEEE
DDDGPGIDELESAQVIKPFVRGQHSRGNSGHGMGLAIVDRIGCWMNAPLRIGRSPELGGA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCC
RMSLKFKAEV
EEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]