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The map label for this gene is sigM [H]

Identifier: 160875973

GI number: 160875973

Start: 3412866

End: 3413429

Strand: Direct

Name: sigM [H]

Synonym: Sbal195_2863

Alternate gene names: 160875973

Gene position: 3412866-3413429 (Clockwise)

Preceding gene: 160875972

Following gene: 160875974

Centisome position: 63.82

GC content: 48.94

Gene sequence:

>564_bases
ATGTTTGCTAACTGGCGTAAGAAATCCGTCGAGCCCGCGGTCTCTTCTGACATGCTAAGTAAACAACGACGATACAACAG
CCTAGTCAAGGCGCTACATGCAGATATCTTCCGCTACGCCTACTGGTTATGCGGCGATAAACACGTGGCTGAAGACATTA
CCCAAGAAACCTTCTTGCGGGCGTGGCGCTCTTTGGATTCCCTCAAGGATGATAAAGCGGCGAAGGCATGGCTGATCACG
ATTCTTCGGCGTGAAAATGCGCGGCGTTTCGAGCGTAAACAGTTCGATTATTCCGACGTTGAGCAAGATACCTTAGAGGA
CAATATCTCCAATAGCAGTGAAGAGCAGACCGAGCAATACCTGATCCGTCGGCAAATTGGCAAGCTAGATATCGAATACC
GCGAGCCACTCTTACTCCAACTGATTGGTGGCTTTAGCGGCGATGAAATTGCCGAGCTGATGGAGCTCAATCGCAACACC
GTAATGACGCGTTTATTTCGGGCGAGGAGCCAATTGAAAGAATTACTTGAGAAGAATGATGTGAGAGGTCAATCCAATGG
ATGA

Upstream 100 bases:

>100_bases
GCCATTAAGCCCACTGAATCCTAGATAAATTAAGGGTTTAATGACAGAGAAGCGAGCTCAACTATGCTAAAAATTCAGCC
AACAAGCCGAAAAAATAAAA

Downstream 100 bases:

>100_bases
GCTTAAATTTAGACGTCAAGCTTATGAAGATCCTCATAATCAAGATGCTGATTTTCTGGCGCAAATTAATGCTAAGCCAG
AAAACCAAGCCTTAATCAAT

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MFANWRKKSVEPAVSSDMLSKQRRYNSLVKALHADIFRYAYWLCGDKHVAEDITQETFLRAWRSLDSLKDDKAAKAWLIT
ILRRENARRFERKQFDYSDVEQDTLEDNISNSSEEQTEQYLIRRQIGKLDIEYREPLLLQLIGGFSGDEIAELMELNRNT
VMTRLFRARSQLKELLEKNDVRGQSNG

Sequences:

>Translated_187_residues
MFANWRKKSVEPAVSSDMLSKQRRYNSLVKALHADIFRYAYWLCGDKHVAEDITQETFLRAWRSLDSLKDDKAAKAWLIT
ILRRENARRFERKQFDYSDVEQDTLEDNISNSSEEQTEQYLIRRQIGKLDIEYREPLLLQLIGGFSGDEIAELMELNRNT
VMTRLFRARSQLKELLEKNDVRGQSNG
>Mature_187_residues
MFANWRKKSVEPAVSSDMLSKQRRYNSLVKALHADIFRYAYWLCGDKHVAEDITQETFLRAWRSLDSLKDDKAAKAWLIT
ILRRENARRFERKQFDYSDVEQDTLEDNISNSSEEQTEQYLIRRQIGKLDIEYREPLLLQLIGGFSGDEIAELMELNRNT
VMTRLFRARSQLKELLEKNDVRGQSNG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22054; Mature: 22054

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFANWRKKSVEPAVSSDMLSKQRRYNSLVKALHADIFRYAYWLCGDKHVAEDITQETFLR
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AWRSLDSLKDDKAAKAWLITILRRENARRFERKQFDYSDVEQDTLEDNISNSSEEQTEQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHH
LIRRQIGKLDIEYREPLLLQLIGGFSGDEIAELMELNRNTVMTRLFRARSQLKELLEKND
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VRGQSNG
CCCCCCC
>Mature Secondary Structure
MFANWRKKSVEPAVSSDMLSKQRRYNSLVKALHADIFRYAYWLCGDKHVAEDITQETFLR
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AWRSLDSLKDDKAAKAWLITILRRENARRFERKQFDYSDVEQDTLEDNISNSSEEQTEQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHH
LIRRQIGKLDIEYREPLLLQLIGGFSGDEIAELMELNRNTVMTRLFRARSQLKELLEKND
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VRGQSNG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]