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The map label for this gene is ykoW [H]

Identifier: 160875961

GI number: 160875961

Start: 3396055

End: 3400314

Strand: Direct

Name: ykoW [H]

Synonym: Sbal195_2851

Alternate gene names: 160875961

Gene position: 3396055-3400314 (Clockwise)

Preceding gene: 160875960

Following gene: 160875962

Centisome position: 63.51

GC content: 36.67

Gene sequence:

>4260_bases
ATGCCTAAAGCACTCTTTAAAATCGTCTTGCTCGCTTTCTTTGGCTTGCATGCATTCGAAGACGTAAACGCATCTCCCTT
TTCTGATAAATCTCCAATTATTCTCCAATCACAATCTTTTGGTGTCCCGCAAGGACTTTCCCAAAGCACAGTTACGTCTA
TAGTCCAGGACCATGATGGCTATCTATGGATTGGAACATTTAATGGACTTAATCGATTTGATGGGAAAAACTTTAAGCAT
TTTTATGCAAATGATGCCAGAACAGGCCTTCCCAGTTCTTTTATCAGAAGTTTACTCATTGATGAACAAGGCGTGTTATA
TGTTGGAACCGATAGTGGTCTAGTCGTATATGATAAACTGCAAGAATCATTTTCTCATTATGGCCTATCGGTAAATGACT
CCCCAGTCTGGAGCCTCAACTCAAGTGATAAGAGTTTAATTGTTGGAACCAACAAAGCAATTATTGATATAAGTAACAAA
GAGCAAACTTATGAACTGTCAAAGAAAGGCCTAAGTGAAATTAAAAAAACGATAAAAGTAGGCGACGATTATTATATAAG
AGACTATGCAGGTACATTATTTGAACTAAGCGGGAGTGAGTTAAAAGAGATAGCTCGAAAAACAATGGATTTCGAGCAAA
AGAATGACACGACAATGCTAATATCATTCAGTGATGGATTATATGAATACGAAGGCAATGAAATAGTAAAAGTCGATAAT
CGAGCGTTTTCATTACTTACAAAATACAAAAAAAACATATATGGCTTCACAAATGAAAATATTGTTGATATTTCCAACAA
CACTACTATTGGACTTTTATCTCCAGATAGACCTGACAAAACGTCTTCATTTTTTGCAACCGAAGATATGTTTATATTAG
GAAGTATTGATCAAGGCATCACTATTGTTAAAAAAGTAAATAATTTAGTGCAAAAAACCAACTTGACGACAGATAGCACA
TGGCATCTTACAAAAAATACTAAAGGTTTTCTGGTTTCATCTGACGCTGAAAAAATAAAACTTTTTGATGAAAATCTAAA
CCTAATAAAAAGTTTCAACACTCATACTCAAGGATACAAATACGCAGTTCTAAGTGACGATGGGCTTTATTTTGGTACTA
ATACAGGGTTGTTTTTACAGAAAGATGATTCATCCAAGTTGATTAGCAAAAATATAATATCATCACTCTCTATTAATGAA
AATAGCTTGACAATTGCTGCTGGCACACCTGACGGTAAAGTTTTAATCATCAAAAATGGTGAAATTACTAACAGCATTGA
TACAAAAAAGAATGAGCCAATTTTTGACGTAGAGTTAACATCTGACAACCTAATATATATAGCTGGACAAGATGGACTAA
AAAAATATGAAAATGGGTTATTAGAAAGCTTAAGCAATGAAATAACTTACAGCATCGAAAAAAGTGATAATGGCATTTAC
TTTGGAACATCAACATCACTGATGCTTTATAATGATACCAATAAAAAAATTTCGAGAATACTCTCTAACAATAAAGAGAT
CTACGCCATTGTAGATAATGATGGTTTTATAACAGCCTCATCACTAAGTGAAGTCATTATTTTTGAAAAAAACAGTAAAG
TATCTTATATCTTAAAAACATCAAATGGGAGTCAATATGAGTACAACGCTCCCAATGGTATCAATATAAATGGTAACACT
CTACTTGCGGGGATTAGTGGGATTAGTCTAGTATCACCTAAAGATGTTGTAAGTTATGTAAAGAAAAGCAAGGTAAATAA
AACAGAAATATCAGATTTCTTAGTATTTAATATAGTTCAAAATCAAGAAAGCAACTATCTAGCACAATCAATCGCAGCAT
CTAATGAAATATCATTGAAATACTCTGACTATCCATTTTCGTTCAACTTTATATCTCCCATGTCAGACGACTCATCAACT
AACTACTACTATAGAATGTTCGGTCTTTCTGATATATGGATACCTGCAAATGGAACAAACTCAGCAACATATACAAACCT
ATCTCCAGGAAATTATACTTTTCAAGTTTATGCTGTTAATTCACTTTCCGGTGAAAAAGCAGCAACAAAAGAGCTTACTG
TCATTATAACACCTCCTTGGTGGTCATCATTTCAAGCAAAATCTATTTATGCTGCTATTGTATTATTTATTTCCTACCTT
GTGACAAAAGCCATATTACGTCGTAGAGAAACACAAAGACAGATTGTACTCAGTGAAGAACGATTAAAATTATCATTATG
GGGAAGTGGTGATGAAATGTGGGACTGGGATATAGAAACTGGCAACATTTTCCGCTCAAATATCTGGGGAGCACTTGAAT
TTCCCCGTGATGGACACCGTTCTGGTAAATCAGATGAAGAGAGCAATATACATCCAATGGATCAAGAGCGTGTTCGAGAA
GCGCTCAATAAGCATTTTTATGGTGAAACAGATCATTTTGAAGCCGCATACCGAGTAAAAGGTAAAGACGACAATTGGGT
ATGGATCCTAGACCGCGCCAAAATTGTAGAACGTGATGAAAAAGATAATGCCCTGCGAATGACTGGAACGATTAAGAATA
TTAGTCAATTTAAACAAAAAGAAGAGCAACTAAAACTCTTTGAAAAGGCTATTGAAAATATTTCGGAAGGCATGTTTATC
CTCGACAGCGAATACCGTTTTGTCGAAGTTAATGAAGCTTGCTGTAAGATTTCATTACGTAACCGAACTGATTTTATTGG
TAACTTACTCACATTTGATTTATATCCTGAAACCTTCTCCACCCAAATCAGGACCATGTTGAAACAACAAGGTCGCTGGG
CAAATGAAGTAGAAGCCGCAAGAGGAGATAAAAGTCACTTCCACATGGAGCTCACTATCGATGCTATCTATGATGAGTTA
GGCGAATTGTCACACTATGTCGGGGTTTTTTCGGATATTTCGAGACGGAAACAGCAAGAAGAAGAACTTAGAAAACTAAC
CAATAATGATCTTTTAACCGGACTACCTAATCGCTCCAACTTACAAGTGACCTTAAGTAACTTAGTGAATCGTGAAATAG
CCCATGCGCTAATGGTGCTTGACCTTGATAATTTTAAGCGTATTAATGATTCATTAGGTCACCAGATTGGAGATACATTA
TTAAAGCTCGTTGCTGCCCGCATTAAGTCCTTACTTCCTAAAAATACCAGTATTTACCGTCTAGGCGGAGATGAATTCGC
CATTGTATTAGATAAAAACTCAGATATAAGCGCCAGTGCTGCCATCGCTAACCGTATTATCGAAGGGTTAAAACCCGCTT
TTGAAGTGAGTAATGAGCAACTAGTCCTAGGATTAAGTATTGGTATAGTGCTATTCCCAGAAGATGAGCAAAGCGAGCAA
GCATTACTGAGGAAAGCAGATATTGCCATGTACCATGCTAAGTCAGCGGGAGGTAATTGCTATCAGTTTTATTCAGAGTC
ATTAAATCAGCATGCGATTAGGCAGTTAGAAATAGAGAATCTTATCCGTGAAGGCTTAAAAGATGATCTATTTGAAGTTT
ATTATCAGCCTAAGGTTGATCTTAAGCGTGGTAAAATTGCAGGCATGGAGGCTTTGGTCAGATTAAATCATCCAGTACAT
GGCTTGATACCCCCAAATGATTTTATTCCACTTGCTGAGGAAAACGGCTTAATTGTTGAAATTGGTGAAATCGTCTTACG
CAAAGCCTGTTTCGCAGCACAGAAATGGCGTGAACAAGGAATATTCAGCGGCAGAGTCGCCGTCAATTTATCGTCACGTC
AATTTGCTCTCCCCGATATCCAGCAACGAATAGAGTCAATTTTAAGACTCACCAAACTCCCCGCTTGTCACCTTGAATTA
GAAATAACAGAAGGTACTGTCATTAAGCAGCCGGAAACGGCGATTATTGTCATGCAGCAACTGGCTAAAATGGGCGTTAG
TTTGGCACTCGATGATTTCGGCACTGGGTACTCGTCCCTTTCATACTTAAAACGTTTCCCGATTCATACTTTAAAAATTG
ATAAAGCTTTTGTTGACGATATTGATAAGTCTGATCGCGATCTCAAAATGGTCGATTCTATTATCACTATCGCCCATAAC
ATGGGGCTTTCTGTTGTGGGTGAAGGAGTAGAACAGACTGCGCAATTAAACATTTTACGAGCACTTAACTGTGAAGAGAT
CCAAGGCTATATCTTTAGTAAGGCTATAAAAGAGACCGAGTTTACCCTGCTACTCCAAGGAGACATGATAAAGCCAAACA
CCCAAAGTAACATTAGTTAA

Upstream 100 bases:

>100_bases
GGATTTTTAGCAGCCTCAGCTTTGACAAAGCCCTCACTTTCTGGAAAAGTGATGTAACACAATTGTTTCATGGCATCCTC
GGATAATAAGAATAAACACT

Downstream 100 bases:

>100_bases
TCATTTAAATCTCAATTTGATTGCGACTTACAACATTGGCACAACAAGTGCATTAGCACTATCAGTGTCAATAATAAATC
AATATCAACTACCCTGAGAG

Product: PAS/PAC and GAF sensor(s)-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1419; Mature: 1418

Protein sequence:

>1419_residues
MPKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDGYLWIGTFNGLNRFDGKNFKH
FYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKLQESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNK
EQTYELSKKGLSEIKKTIKVGDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
RAFSLLTKYKKNIYGFTNENIVDISNNTTIGLLSPDRPDKTSSFFATEDMFILGSIDQGITIVKKVNNLVQKTNLTTDST
WHLTKNTKGFLVSSDAEKIKLFDENLNLIKSFNTHTQGYKYAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINE
NSLTIAAGTPDGKVLIIKNGEITNSIDTKKNEPIFDVELTSDNLIYIAGQDGLKKYENGLLESLSNEITYSIEKSDNGIY
FGTSTSLMLYNDTNKKISRILSNNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKTSNGSQYEYNAPNGININGNT
LLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQNQESNYLAQSIAASNEISLKYSDYPFSFNFISPMSDDSST
NYYYRMFGLSDIWIPANGTNSATYTNLSPGNYTFQVYAVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
VTKAILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHRSGKSDEESNIHPMDQERVRE
ALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDEKDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFI
LDSEYRFVEVNEACCKISLRNRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVLDLDNFKRINDSLGHQIGDTL
LKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASAAIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQ
ALLRKADIAMYHAKSAGGNCYQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPVH
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDIQQRIESILRLTKLPACHLEL
EITEGTVIKQPETAIIVMQQLAKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHN
MGLSVVGEGVEQTAQLNILRALNCEEIQGYIFSKAIKETEFTLLLQGDMIKPNTQSNIS

Sequences:

>Translated_1419_residues
MPKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDGYLWIGTFNGLNRFDGKNFKH
FYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKLQESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNK
EQTYELSKKGLSEIKKTIKVGDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
RAFSLLTKYKKNIYGFTNENIVDISNNTTIGLLSPDRPDKTSSFFATEDMFILGSIDQGITIVKKVNNLVQKTNLTTDST
WHLTKNTKGFLVSSDAEKIKLFDENLNLIKSFNTHTQGYKYAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINE
NSLTIAAGTPDGKVLIIKNGEITNSIDTKKNEPIFDVELTSDNLIYIAGQDGLKKYENGLLESLSNEITYSIEKSDNGIY
FGTSTSLMLYNDTNKKISRILSNNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKTSNGSQYEYNAPNGININGNT
LLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQNQESNYLAQSIAASNEISLKYSDYPFSFNFISPMSDDSST
NYYYRMFGLSDIWIPANGTNSATYTNLSPGNYTFQVYAVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
VTKAILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHRSGKSDEESNIHPMDQERVRE
ALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDEKDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFI
LDSEYRFVEVNEACCKISLRNRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVLDLDNFKRINDSLGHQIGDTL
LKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASAAIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQ
ALLRKADIAMYHAKSAGGNCYQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPVH
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDIQQRIESILRLTKLPACHLEL
EITEGTVIKQPETAIIVMQQLAKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHN
MGLSVVGEGVEQTAQLNILRALNCEEIQGYIFSKAIKETEFTLLLQGDMIKPNTQSNIS
>Mature_1418_residues
PKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDGYLWIGTFNGLNRFDGKNFKHF
YANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKLQESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNKE
QTYELSKKGLSEIKKTIKVGDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDNR
AFSLLTKYKKNIYGFTNENIVDISNNTTIGLLSPDRPDKTSSFFATEDMFILGSIDQGITIVKKVNNLVQKTNLTTDSTW
HLTKNTKGFLVSSDAEKIKLFDENLNLIKSFNTHTQGYKYAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINEN
SLTIAAGTPDGKVLIIKNGEITNSIDTKKNEPIFDVELTSDNLIYIAGQDGLKKYENGLLESLSNEITYSIEKSDNGIYF
GTSTSLMLYNDTNKKISRILSNNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKTSNGSQYEYNAPNGININGNTL
LAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQNQESNYLAQSIAASNEISLKYSDYPFSFNFISPMSDDSSTN
YYYRMFGLSDIWIPANGTNSATYTNLSPGNYTFQVYAVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYLV
TKAILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHRSGKSDEESNIHPMDQERVREA
LNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDEKDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFIL
DSEYRFVEVNEACCKISLRNRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDELG
ELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVLDLDNFKRINDSLGHQIGDTLL
KLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASAAIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQA
LLRKADIAMYHAKSAGGNCYQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPVHG
LIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDIQQRIESILRLTKLPACHLELE
ITEGTVIKQPETAIIVMQQLAKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNM
GLSVVGEGVEQTAQLNILRALNCEEIQGYIFSKAIKETEFTLLLQGDMIKPNTQSNIS

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=437, Percent_Identity=39.5881006864989, Blast_Score=312, Evalue=8e-86,
Organism=Escherichia coli, GI87081921, Length=449, Percent_Identity=32.293986636971, Blast_Score=247, Evalue=3e-66,
Organism=Escherichia coli, GI226510982, Length=444, Percent_Identity=28.3783783783784, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1788502, Length=285, Percent_Identity=32.9824561403509, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=29.2134831460674, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI87081743, Length=229, Percent_Identity=33.1877729257642, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1790496, Length=256, Percent_Identity=31.25, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=30.2521008403361, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=31.25, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI1787055, Length=237, Percent_Identity=30.8016877637131, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI87082096, Length=421, Percent_Identity=26.603325415677, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1788849, Length=241, Percent_Identity=29.4605809128631, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1788381, Length=437, Percent_Identity=24.9427917620137, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=35.7142857142857, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI145693134, Length=185, Percent_Identity=34.5945945945946, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=35.9756097560976, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=34.7560975609756, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI87081881, Length=184, Percent_Identity=32.6086956521739, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787802, Length=159, Percent_Identity=31.4465408805031, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789650, Length=446, Percent_Identity=20.4035874439462, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788085, Length=187, Percent_Identity=28.3422459893048, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 159498; Mature: 159367

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCC
YLWIGTFNGLNRFDGKNFKHFYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKL
EEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEHHH
QESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNKEQTYELSKKGLSEIKKTIKV
HHHHHHCCCCCCCCCEEEECCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHC
GDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
CCCEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCEEEEECC
RAFSLLTKYKKNIYGFTNENIVDISNNTTIGLLSPDRPDKTSSFFATEDMFILGSIDQGI
HHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCH
TIVKKVNNLVQKTNLTTDSTWHLTKNTKGFLVSSDAEKIKLFDENLNLIKSFNTHTQGYK
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCEEEEECCCCHHHHHCCCCCCCEE
YAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINENSLTIAAGTPDGKVLIIKNG
EEEEECCCEEEECCCEEEEEECCCHHHHHHHHHHHCEECCCCEEEEECCCCCEEEEEECC
EITNSIDTKKNEPIFDVELTSDNLIYIAGQDGLKKYENGLLESLSNEITYSIEKSDNGIY
CCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
FGTSTSLMLYNDTNKKISRILSNNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKT
EECCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCEEECCCCCEEEEEECCCCEEEEEEC
SNGSQYEYNAPNGININGNTLLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQ
CCCCEEEECCCCCEEECCCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHHEEEEEEEC
NQESNYLAQSIAASNEISLKYSDYPFSFNFISPMSDDSSTNYYYRMFGLSDIWIPANGTN
CCCCHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCC
SATYTNLSPGNYTFQVYAVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
CCEEEECCCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
VTKAILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHR
HHHHHHHHHHHHHHEEEECCEEEEEEECCCCCEEEEECCCCCEEECCCCEEEECCCCCCC
SGKSDEESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCHHHCCCC
KDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFILDSEYRFVEVNEACCKISLR
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEEC
NRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
CCHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEHHHHHHHH
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEHHHHHHHHHHHHEEEE
DLDNFKRINDSLGHQIGDTLLKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCHHH
AIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQALLRKADIAMYHAKSAGGNC
HHHHHHHHHCCHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHEEEEECCCCCCH
YQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEE
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDI
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
QQRIESILRLTKLPACHLELEITEGTVIKQPETAIIVMQQLAKMGVSLALDDFGTGYSSL
HHHHHHHHHHHCCCCEEEEEEEECCEEEECCCHHHHHHHHHHHCCCEEEECCCCCCHHHH
SYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNMGLSVVGEGVEQTAQLNILR
HHHHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHH
ALNCEEIQGYIFSKAIKETEFTLLLQGDMIKPNTQSNIS
HCCHHHHHHHHHHHHHCCCEEEEEEECCEECCCCCCCCC
>Mature Secondary Structure 
PKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCC
YLWIGTFNGLNRFDGKNFKHFYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKL
EEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEHHH
QESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNKEQTYELSKKGLSEIKKTIKV
HHHHHHCCCCCCCCCEEEECCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHC
GDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
CCCEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCEEEEECC
RAFSLLTKYKKNIYGFTNENIVDISNNTTIGLLSPDRPDKTSSFFATEDMFILGSIDQGI
HHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCH
TIVKKVNNLVQKTNLTTDSTWHLTKNTKGFLVSSDAEKIKLFDENLNLIKSFNTHTQGYK
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCCEEEEECCCCHHHHHCCCCCCCEE
YAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINENSLTIAAGTPDGKVLIIKNG
EEEEECCCEEEECCCEEEEEECCCHHHHHHHHHHHCEECCCCEEEEECCCCCEEEEEECC
EITNSIDTKKNEPIFDVELTSDNLIYIAGQDGLKKYENGLLESLSNEITYSIEKSDNGIY
CCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
FGTSTSLMLYNDTNKKISRILSNNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKT
EECCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCEEECCCCCEEEEEECCCCEEEEEEC
SNGSQYEYNAPNGININGNTLLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQ
CCCCEEEECCCCCEEECCCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHHEEEEEEEC
NQESNYLAQSIAASNEISLKYSDYPFSFNFISPMSDDSSTNYYYRMFGLSDIWIPANGTN
CCCCHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCC
SATYTNLSPGNYTFQVYAVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
CCEEEECCCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
VTKAILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHR
HHHHHHHHHHHHHHEEEECCEEEEEEECCCCCEEEEECCCCCEEECCCCEEEECCCCCCC
SGKSDEESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCHHHCCCC
KDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFILDSEYRFVEVNEACCKISLR
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEEC
NRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
CCHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEHHHHHHHH
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEHHHHHHHHHHHHEEEE
DLDNFKRINDSLGHQIGDTLLKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCHHH
AIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQALLRKADIAMYHAKSAGGNC
HHHHHHHHHCCHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHEEEEECCCCCCH
YQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEE
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDI
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
QQRIESILRLTKLPACHLELEITEGTVIKQPETAIIVMQQLAKMGVSLALDDFGTGYSSL
HHHHHHHHHHHCCCCEEEEEEEECCEEEECCCHHHHHHHHHHHCCCEEEECCCCCCHHHH
SYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNMGLSVVGEGVEQTAQLNILR
HHHHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHH
ALNCEEIQGYIFSKAIKETEFTLLLQGDMIKPNTQSNIS
HCCHHHHHHHHHHHHHCCCEEEEEEECCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]