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The map label for this gene is pepV [H]

Identifier: 160875849

GI number: 160875849

Start: 3246482

End: 3248125

Strand: Reverse

Name: pepV [H]

Synonym: Sbal195_2738

Alternate gene names: 160875849

Gene position: 3248125-3246482 (Counterclockwise)

Preceding gene: 160875854

Following gene: 160875848

Centisome position: 60.74

GC content: 49.21

Gene sequence:

>1644_bases
ATGTCTCAATCTGGTATTCAACATGCTCGCGTGCGTCGAGCGTTATCCTTGGCATTACTGACTGCGTCCAGCTGGGTTAT
GCCGCAATGTATTGCAGCGCCAGCAACAACAGCGGCTCACACAAACGTCCCCCAGTTAAGCCAAAATGCACTAAAGGTCG
CCGATTACGCGGTCGCAAAATACGATGCGGCTATGGTGCAGAGTTTGACTCAGTTGGTGAGTTTTAATACCCAAGCGGTT
GAAGGGCAAACGCCAGATACCAATCCCGCCTTTGTGGGCTTCAAGTCGAGTTTAAAGCAACTCAGTCAGGATCTCGGGTT
AGATTATGCCGATCATGGTTATGTTGTGTTGATTGGCTTAGATGCCAATTCGGCTGTAAACAATGAATCTAAAAAGTTAG
GCATAGTCACCCACGGCGATGTGCAACCAGCTAATCCTGCATTGTGGGCGCAGAGCCCTTATCTGCTTGATACTCAATCG
GAACCGGGCAAACTGATTGGTCGCGGCACAGAGGACGACAAGGGCGCCATCGTTACCGCCATGTATGCGATGAAGGCGAT
TAAAGATAAACACATTAAGCGAGATAGACGCATTGAACTCTTGGTTTATCTTGCTGAAGAGTCCGACTGGGAACCACTGA
AAACCTTTTTAGCCAGCTACACGCCAGCGGACATGAACATTACTATCGATGCCGAATACCCCGTGGTTACCGCCGAGAAA
GGTTGGAGTAAGATTACCTTTACTGTGCCCAATATTACGATCTCCAATATAGAAGCTAAAGCAGAGGCTTCAACTCAAGC
GCCCACGTTAACGGCTTTCTCTGGTGGCTATTTTGCCAGCCAAGTACCGCAGCAGGCTGAAGCAGAAATTGAGGCGGTTT
CACCCGCATTACTGACAAAGTTACAGACCAGAGCCGCCGCGCAGCAGGGGATGAAATATCGTTTTGAAAACCATTGCGTC
GATAAACAGTGCAACTTGCATATCTTTGCCGACGGTAAAGCCGCCCATTCATCCACTCCTGAAGATGGAGTGAATGCTGT
GACCCATTTGGCGGCATTGTTAAGTCCCGAATTGAATGATAAACCTTGGCCGAAAACTAGCGCATCCTTAACTGTCGCCG
CCATGAACGAGCTGGTGGGGTTAGGCATTTATGCCGAGCAATTTGGTGACTTAGCCTATAAAGATGATTTTATGGGACCG
CTGACCTTAGCCCCAACTGTGGTGGTGCAAACTCAGAAGGGCACTGAGGTGACCATTAACTTGCGTCGTCCCGTCGGCAA
AACACCAGAGTTACTCACTAAGCAAGCCCGTGAAGCCCTAGCACTGTGGCAGGAGAAACATCAAGTGCAACTTGCTGATA
TCGAAAGTTATTGGGGCGAGCCTATGGTGATGAAAGGTGCGCCGCAGCAACAAACCCTGCTCGACGTGTTTGCCCACTTC
ACTGGCATAGTCGACCCTAAACCCGTTGCAATCGGCGGCTCAACCAACAGTAAATTATTCCCCAATGCCTTAAGTTTTGG
CCCTGCCATGCCGGGCGTGGAATACACTGGCCATACTGAAAAAGAGTTCATCACCCATAAGCAATTTATGCTGAATCTAA
AAATGTACACCGCAGCGTTTATCGAGCTATCGGCGGTTAAATAG

Upstream 100 bases:

>100_bases
ACTGGCGTAAGCCACACCTTGCACTAAACCAGCTTAATCCATTTTCAACCGTCTCTTGCAGTACGGTCCTAAAACACGAA
TAACAATAATAGGATCTTCT

Downstream 100 bases:

>100_bases
CGCTCTTTGTGAAAGTGATTTTGGGATGGCACAAAAGTGTTGGGTAGAAATAAAGTCTGTATCAAGTATTAAGCTAAGCA
TTAAGGGTTAATAGAACTAT

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAHTNVPQLSQNALKVADYAVAKYDAAMVQSLTQLVSFNTQAV
EGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGLDANSAVNNESKKLGIVTHGDVQPANPALWAQSPYLLDTQS
EPGKLIGRGTEDDKGAIVTAMYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
GWSKITFTVPNITISNIEAKAEASTQAPTLTAFSGGYFASQVPQQAEAEIEAVSPALLTKLQTRAAAQQGMKYRFENHCV
DKQCNLHIFADGKAAHSSTPEDGVNAVTHLAALLSPELNDKPWPKTSASLTVAAMNELVGLGIYAEQFGDLAYKDDFMGP
LTLAPTVVVQTQKGTEVTINLRRPVGKTPELLTKQAREALALWQEKHQVQLADIESYWGEPMVMKGAPQQQTLLDVFAHF
TGIVDPKPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELSAVK

Sequences:

>Translated_547_residues
MSQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAHTNVPQLSQNALKVADYAVAKYDAAMVQSLTQLVSFNTQAV
EGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGLDANSAVNNESKKLGIVTHGDVQPANPALWAQSPYLLDTQS
EPGKLIGRGTEDDKGAIVTAMYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
GWSKITFTVPNITISNIEAKAEASTQAPTLTAFSGGYFASQVPQQAEAEIEAVSPALLTKLQTRAAAQQGMKYRFENHCV
DKQCNLHIFADGKAAHSSTPEDGVNAVTHLAALLSPELNDKPWPKTSASLTVAAMNELVGLGIYAEQFGDLAYKDDFMGP
LTLAPTVVVQTQKGTEVTINLRRPVGKTPELLTKQAREALALWQEKHQVQLADIESYWGEPMVMKGAPQQQTLLDVFAHF
TGIVDPKPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELSAVK
>Mature_546_residues
SQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAHTNVPQLSQNALKVADYAVAKYDAAMVQSLTQLVSFNTQAVE
GQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGLDANSAVNNESKKLGIVTHGDVQPANPALWAQSPYLLDTQSE
PGKLIGRGTEDDKGAIVTAMYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEKG
WSKITFTVPNITISNIEAKAEASTQAPTLTAFSGGYFASQVPQQAEAEIEAVSPALLTKLQTRAAAQQGMKYRFENHCVD
KQCNLHIFADGKAAHSSTPEDGVNAVTHLAALLSPELNDKPWPKTSASLTVAAMNELVGLGIYAEQFGDLAYKDDFMGPL
TLAPTVVVQTQKGTEVTINLRRPVGKTPELLTKQAREALALWQEKHQVQLADIESYWGEPMVMKGAPQQQTLLDVFAHFT
GIVDPKPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELSAVK

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 59347; Mature: 59216

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAHTNVPQLSQNALKVADYAVAK
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
YDAAMVQSLTQLVSFNTQAVEGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCEEEEEEE
DANSAVNNESKKLGIVTHGDVQPANPALWAQSPYLLDTQSEPGKLIGRGTEDDKGAIVTA
CCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCEEEECCCCCCCEEECCCCCCCCHHHHH
MYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCEEECCC
GWSKITFTVPNITISNIEAKAEASTQAPTLTAFSGGYFASQVPQQAEAEIEAVSPALLTK
CCCEEEEEECCEEEECCEECCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHCCHHHHHH
LQTRAAAQQGMKYRFENHCVDKQCNLHIFADGKAAHSSTPEDGVNAVTHLAALLSPELND
HHHHHHHHHCCCEEHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
KPWPKTSASLTVAAMNELVGLGIYAEQFGDLAYKDDFMGPLTLAPTVVVQTQKGTEVTIN
CCCCCCCCCEEHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCEEEEE
LRRPVGKTPELLTKQAREALALWQEKHQVQLADIESYWGEPMVMKGAPQQQTLLDVFAHF
ECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHH
TGIVDPKPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAF
HCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEE
IELSAVK
EEEEECC
>Mature Secondary Structure 
SQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAHTNVPQLSQNALKVADYAVAK
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
YDAAMVQSLTQLVSFNTQAVEGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCEEEEEEE
DANSAVNNESKKLGIVTHGDVQPANPALWAQSPYLLDTQSEPGKLIGRGTEDDKGAIVTA
CCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCEEEECCCCCCCEEECCCCCCCCHHHHH
MYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCEEECCC
GWSKITFTVPNITISNIEAKAEASTQAPTLTAFSGGYFASQVPQQAEAEIEAVSPALLTK
CCCEEEEEECCEEEECCEECCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHCCHHHHHH
LQTRAAAQQGMKYRFENHCVDKQCNLHIFADGKAAHSSTPEDGVNAVTHLAALLSPELND
HHHHHHHHHCCCEEHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
KPWPKTSASLTVAAMNELVGLGIYAEQFGDLAYKDDFMGPLTLAPTVVVQTQKGTEVTIN
CCCCCCCCCEEHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCEEEEE
LRRPVGKTPELLTKQAREALALWQEKHQVQLADIESYWGEPMVMKGAPQQQTLLDVFAHF
ECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEECCCCCHHHHHHHHHHH
TGIVDPKPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAF
HCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEE
IELSAVK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]