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The map label for this gene is lolC [H]

Identifier: 160875621

GI number: 160875621

Start: 2959880

End: 2961112

Strand: Reverse

Name: lolC [H]

Synonym: Sbal195_2509

Alternate gene names: 160875621

Gene position: 2961112-2959880 (Counterclockwise)

Preceding gene: 160875625

Following gene: 160875620

Centisome position: 55.38

GC content: 51.26

Gene sequence:

>1233_bases
ATGAATCCAGGATTTCCTTTCTATATTGGTTACCGTTATTGGCGGGCCAGAAAAGCGAACGCGTTCGCGTCGTTCATTAC
TCTATTTGCCGTTTCAGGCATTTTTTTAGGCGTTGCCGCGCTCATTGTCGTGAGCTCTGTGATGAATGGTCTCGAAGGCC
AACTCAAGCAACGTATCTTAGGCGCAGTACCGCAATTAACTCTTTATAGTGAAGCGCCTTTAGTCGATTGGACTGAGCAG
GCGAGTGCGCTTAAAGCCTTACCTGGCGTATTAGGCGTGACGCCGAGCGTGTCGACGCAGGCCATGGTGCAATCGGCGGC
GAGTATTCGTGCTGTACAGGTTTATGGCGTGTTCCCCGAGTTAGCGGAAAAGTTATCTTCGGTTGCCCAGCACACTTACT
CAGGTGCATTTGAGCAGCTGACGAGCGGCGACTACAAGGTGATTTTAGGCTCTGAGCTGGCAAGGCAACTTAAAGTCGCC
CCTGGTGATACGGTGCGATTATTGAGTGGCGATGGCGTGGTGTATTCGCCCTTAGGTCCAGTGCCGAGTCAACGTAAGTT
TTTGGTCTCGGGCATTTTTGAAATGGGCTCTCAGGTCGATGCGGGCGTGGCATATATCCATTATCAAGATGCGAAACGGC
TGATGCGCCAACCAAGTAAAGAGATCAGTCAACTTAGGCTTTATTTAGCGGATCCTTTCAGCGCACCGGCTTTAGCGCCT
AAAGTGCAGGATATATTAGCTAAACAAGGTTTGAAGGCGACAACCAGCGATTGGCGTGATACCTATGGCCACTTGTTTGG
CGCGGTCAAGATGGAAAAGAACATGATGTCACTGATGTTGAGTCTGATTGTGGCCGTGGCCGCATTCAATATCGTCTCGG
CACTGGTCATGATGGTGGTCGATAAAACCACAGATGTGGCGGTGCTCAAAACTCAAGGCGTGACCACACCCGCCGTGATG
GGCATTTTTGTGGTGCAAGGGTCGCTCAATGCAGTGCTCGGTTTAGTGCTGGGGCTGGCGGTTGGGATACTCATCACCTT
GAATCTGAATGGCATTATGACCACCTTAGGGATTTCTATTCTAGGCGTAGGGCAAAGTTTGCCGGTGAAACTGGAATTGA
TGCAGTTGTCTGTGATCGTGATTGGTACGCTGCTGGTGACCCTGCTGGCGACCTTATATCCCGCACTGCGCGCCGCCAAT
GTGCAACCCGCGACTGCGCTCAGATATGAGTAA

Upstream 100 bases:

>100_bases
GAACAAGGCTTGCCTCTTTATTTATAGGACCAATACCCCTATTATCGTGCCCATCTTCATGATTTAGCAAGTTCAGCACA
CAGGACGCAACCCTCTTTCA

Downstream 100 bases:

>100_bases
CGGTATGCGAATAAACCTGTCGTTGCGACTGAGCGACGATGGAATAACGATTTCAATATACGAATAATTAAATGCATTGA
TTTGATGACATAAATCGATG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNPGFPFYIGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTLYSEAPLVDWTEQ
ASALKALPGVLGVTPSVSTQAMVQSAASIRAVQVYGVFPELAEKLSSVAQHTYSGAFEQLTSGDYKVILGSELARQLKVA
PGDTVRLLSGDGVVYSPLGPVPSQRKFLVSGIFEMGSQVDAGVAYIHYQDAKRLMRQPSKEISQLRLYLADPFSAPALAP
KVQDILAKQGLKATTSDWRDTYGHLFGAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVVDKTTDVAVLKTQGVTTPAVM
GIFVVQGSLNAVLGLVLGLAVGILITLNLNGIMTTLGISILGVGQSLPVKLELMQLSVIVIGTLLVTLLATLYPALRAAN
VQPATALRYE

Sequences:

>Translated_410_residues
MNPGFPFYIGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTLYSEAPLVDWTEQ
ASALKALPGVLGVTPSVSTQAMVQSAASIRAVQVYGVFPELAEKLSSVAQHTYSGAFEQLTSGDYKVILGSELARQLKVA
PGDTVRLLSGDGVVYSPLGPVPSQRKFLVSGIFEMGSQVDAGVAYIHYQDAKRLMRQPSKEISQLRLYLADPFSAPALAP
KVQDILAKQGLKATTSDWRDTYGHLFGAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVVDKTTDVAVLKTQGVTTPAVM
GIFVVQGSLNAVLGLVLGLAVGILITLNLNGIMTTLGISILGVGQSLPVKLELMQLSVIVIGTLLVTLLATLYPALRAAN
VQPATALRYE
>Mature_410_residues
MNPGFPFYIGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTLYSEAPLVDWTEQ
ASALKALPGVLGVTPSVSTQAMVQSAASIRAVQVYGVFPELAEKLSSVAQHTYSGAFEQLTSGDYKVILGSELARQLKVA
PGDTVRLLSGDGVVYSPLGPVPSQRKFLVSGIFEMGSQVDAGVAYIHYQDAKRLMRQPSKEISQLRLYLADPFSAPALAP
KVQDILAKQGLKATTSDWRDTYGHLFGAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVVDKTTDVAVLKTQGVTTPAVM
GIFVVQGSLNAVLGLVLGLAVGILITLNLNGIMTTLGISILGVGQSLPVKLELMQLSVIVIGTLLVTLLATLYPALRAAN
VQPATALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=406, Percent_Identity=41.3793103448276, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI1787362, Length=408, Percent_Identity=32.5980392156863, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43693; Mature: 43693

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPGFPFYIGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRIL
CCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTLYSEAPLVDWTEQASALKALPGVLGVTPSVSTQAMVQSAASIRAVQVYGVFPE
HCCCCEEEECCCCCCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHEEEEEECCCHH
LAEKLSSVAQHTYSGAFEQLTSGDYKVILGSELARQLKVAPGDTVRLLSGDGVVYSPLGP
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCEEECCCCC
VPSQRKFLVSGIFEMGSQVDAGVAYIHYQDAKRLMRQPSKEISQLRLYLADPFSAPALAP
CCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCH
KVQDILAKQGLKATTSDWRDTYGHLFGAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKTTDVAVLKTQGVTTPAVMGIFVVQGSLNAVLGLVLGLAVGILITLNLNGIMTTLGISI
CCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHH
LGVGQSLPVKLELMQLSVIVIGTLLVTLLATLYPALRAANVQPATALRYE
EECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNPGFPFYIGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRIL
CCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTLYSEAPLVDWTEQASALKALPGVLGVTPSVSTQAMVQSAASIRAVQVYGVFPE
HCCCCEEEECCCCCCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHEEEEEECCCHH
LAEKLSSVAQHTYSGAFEQLTSGDYKVILGSELARQLKVAPGDTVRLLSGDGVVYSPLGP
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCEEECCCCC
VPSQRKFLVSGIFEMGSQVDAGVAYIHYQDAKRLMRQPSKEISQLRLYLADPFSAPALAP
CCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCH
KVQDILAKQGLKATTSDWRDTYGHLFGAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKTTDVAVLKTQGVTTPAVMGIFVVQGSLNAVLGLVLGLAVGILITLNLNGIMTTLGISI
CCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHH
LGVGQSLPVKLELMQLSVIVIGTLLVTLLATLYPALRAANVQPATALRYE
EECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]