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The map label for this gene is luxQ [H]

Identifier: 160875458

GI number: 160875458

Start: 2766523

End: 2768442

Strand: Reverse

Name: luxQ [H]

Synonym: Sbal195_2346

Alternate gene names: 160875458

Gene position: 2768442-2766523 (Counterclockwise)

Preceding gene: 160875459

Following gene: 160875457

Centisome position: 51.77

GC content: 43.39

Gene sequence:

>1920_bases
ATGAGCGTTAAATACAGTGCTTGCATCAATATGTTCAGTGGCTTATGGGTCACAATATTAGTGCTGTGGCTAACCTTGTC
CCACTCGCTGTATGAGTTTGACGCTATTTACGATAAAAAGGCGCAGGCGGTTTTTACTTCCTCGCGGGATATGTTCATAC
AACATAAGATCATGTTGGATGCGCTGAAATCTTTTTTCCACGCGTCGAGTAAGGTGACGTCAGAGGAGTTTGAGATTTTT
GCCAAGGATTTACTTAAGATCAAATCTGCCGTCGCTTTTACGCTGACCCCCAGTCTTGAACTGGCCTATATCTCAGATCA
GACTATGGCTACTGAGCTTAAACAGTTTGAGCTAGTCAAGGAGCCTAAAGGGGAGCTTAAGGCGAGCCTTGCCAATTACA
CTTTGGCTGTGGTGGCCATTGATAAGCCTAATATGCCTTATCTCGTTTATGCCGTTTCTCATCAGCGGATACTCGCGCGA
ATCGAACAAGAGCAGGGCGTTTGCATTACCTATCAATTTGAACAGTCATTTGAGCAGTCGTTACTGCAAAACTCATTCTG
TAATCTTAAGTTAGCCAGCGGCCTATTTTCATTATTTAATTACTCTGATAGCCAAACCTTAGCTATCCCTGAATATCAAA
CCCGAGTGAGTTTACAGGTACAATATCAAGTGCCGCAAAAAGAAATTATCGAGCTTATCGTGATCATCCTACTGATTGCA
GCCCTTGGCATAGTTTTGTCCTTCCTTTTGTACTTTAAGTCTAAAAATCAGCAGGTTGTTGAGCAAATTAAGCTCGACAA
TCGCGCTAAATTAGCCGTGCTTTCGAGCATTAATCATGAGATCCGCACCCCAATCAATGCCATTCTTGGCTATAGTCGCA
TGCTAAAAAAAGCCCTCTCACAACCACAGGAACTGGATAAAATCGTCGATAAAATGGCCTGGTCTGCCAACTTACTCTAT
TCGGTTGCCGAAAATACCTTAAATTACAGTAAGGCAGAAGCTGGGCAGTTAAAACTGAATTTACATTCGGTGAACTTACA
CGAGTATGTGGGCAATATTCAGGACTATTATCGTGCATTTAGTGCAACCTCCGGCAAACGTTTACACATTGTAGTAAGTG
AGTCTTTGCCGCAGTTTATCGAACTCGATGGGACTAAGTTATTCCAACTCATGACCAACATTATCAATAATGCGTTCAAA
TACAGTACGGGTAGCGAAGTGCATTGCTATATGGATTTACACCTTAAAGCGAATGCTAAAAATCAGCGCCCTGTGCTTAG
GGTGCTGATCCGCGATTTTGGCGATGGTATGTCAAAGGAAGCGCAGCGCGCTTTAGTCGATCCCTTTATGCACGCCGCTA
ACTCACCTATTGCCGCGACATCGGGTATGGGACTCGGGCTCTATACGTGTAATCGATTGCTTGAGCAGATTGGCGGTCGG
TTTAGGCTGCGCAGTCAAAAGGGCAAAGGTACCACAGTGTTACTGCATTTCCCCTGTCAGCTCAGCGTAGTGAAAGAACG
ATTAACACTTCAATATGATCAACAAAAAGTGCTGATCATAGATGACAATCTGTTTAATCTTGAAATTTGTCGCGCCATGC
TGGAGCACTATCATTTTCAAACCTTCAGTACTGATAATACAGAGCAAGCACTGAAGATGTTGGTTAACCATTTGCCACAG
ATTGTCATTGTGGATTACCGTTTACAAGGAATGAACGGTTTACAACTAGTCAGGCAGATGCAGCAAGTATTACAAAGCCT
GGAGAGTAATAGCCCTATTGAACATCAGTGTCGTTTCTTTTTGCTCTCCGCGAATGACTGCGATGATATTCCCGAGTTAG
CGTCGTTTCCTGAGGTGCATTTCATGCAGAAACCATTTAGTGCCGAAGTCTTTCTCAGCAAATTAGCGGTAAAAGAGTAA

Upstream 100 bases:

>100_bases
TTGCAGCTTAAGAATACCGTGCCTATGGCTAATTCTTGCGAGCGAGAACAGTTTAATCATCAGCTAAACGATTTACTTAA
TACCGTAATGGATTACGCCA

Downstream 100 bases:

>100_bases
ATCATCAATGCATTGAATGTAATCTTGAAATCACATTAGCTGACTTCATCGAATTGAACAGCAATGGTACAAATACCTTT
GCGGTTAGTGTGTGATCTAA

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MSVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFIQHKIMLDALKSFFHASSKVTSEEFEIF
AKDLLKIKSAVAFTLTPSLELAYISDQTMATELKQFELVKEPKGELKASLANYTLAVVAIDKPNMPYLVYAVSHQRILAR
IEQEQGVCITYQFEQSFEQSLLQNSFCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQKEIIELIVIILLIA
ALGIVLSFLLYFKSKNQQVVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALSQPQELDKIVDKMAWSANLLY
SVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAFSATSGKRLHIVVSESLPQFIELDGTKLFQLMTNIINNAFK
YSTGSEVHCYMDLHLKANAKNQRPVLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGLYTCNRLLEQIGGR
FRLRSQKGKGTTVLLHFPCQLSVVKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNTEQALKMLVNHLPQ
IVIVDYRLQGMNGLQLVRQMQQVLQSLESNSPIEHQCRFFLLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE

Sequences:

>Translated_639_residues
MSVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFIQHKIMLDALKSFFHASSKVTSEEFEIF
AKDLLKIKSAVAFTLTPSLELAYISDQTMATELKQFELVKEPKGELKASLANYTLAVVAIDKPNMPYLVYAVSHQRILAR
IEQEQGVCITYQFEQSFEQSLLQNSFCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQKEIIELIVIILLIA
ALGIVLSFLLYFKSKNQQVVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALSQPQELDKIVDKMAWSANLLY
SVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAFSATSGKRLHIVVSESLPQFIELDGTKLFQLMTNIINNAFK
YSTGSEVHCYMDLHLKANAKNQRPVLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGLYTCNRLLEQIGGR
FRLRSQKGKGTTVLLHFPCQLSVVKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNTEQALKMLVNHLPQ
IVIVDYRLQGMNGLQLVRQMQQVLQSLESNSPIEHQCRFFLLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE
>Mature_638_residues
SVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFIQHKIMLDALKSFFHASSKVTSEEFEIFA
KDLLKIKSAVAFTLTPSLELAYISDQTMATELKQFELVKEPKGELKASLANYTLAVVAIDKPNMPYLVYAVSHQRILARI
EQEQGVCITYQFEQSFEQSLLQNSFCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQKEIIELIVIILLIAA
LGIVLSFLLYFKSKNQQVVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALSQPQELDKIVDKMAWSANLLYS
VAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAFSATSGKRLHIVVSESLPQFIELDGTKLFQLMTNIINNAFKY
STGSEVHCYMDLHLKANAKNQRPVLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGLYTCNRLLEQIGGRF
RLRSQKGKGTTVLLHFPCQLSVVKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNTEQALKMLVNHLPQI
VIVDYRLQGMNGLQLVRQMQQVLQSLESNSPIEHQCRFFLLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=331, Percent_Identity=27.190332326284, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI48994928, Length=372, Percent_Identity=25, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=28.5106382978723, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=332, Percent_Identity=26.8072289156627, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=25.6198347107438, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=287, Percent_Identity=23.6933797909408, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72648; Mature: 72517

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFIQHKIMLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHH
ALKSFFHASSKVTSEEFEIFAKDLLKIKSAVAFTLTPSLELAYISDQTMATELKQFELVK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHH
EPKGELKASLANYTLAVVAIDKPNMPYLVYAVSHQRILARIEQEQGVCITYQFEQSFEQS
CCHHHHHHHHCCEEEEEEEECCCCCCEEEEEECHHHHHHHHHHCCCEEEEEHHHHHHHHH
LLQNSFCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQKEIIELIVIILLIA
HHHCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEEECCHHHHHHHHHHHHHHH
ALGIVLSFLLYFKSKNQQVVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALS
HHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHC
QPQELDKIVDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHCCHHHHHHHH
SATSGKRLHIVVSESLPQFIELDGTKLFQLMTNIINNAFKYSTGSEVHCYMDLHLKANAK
HCCCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCC
NQRPVLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGLYTCNRLLEQIGGR
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCC
FRLRSQKGKGTTVLLHFPCQLSVVKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQ
EEEECCCCCCCEEEEECCCHHHHHHHHHHEEECCCEEEEEECCCCCHHHHHHHHHHHCCE
TFSTDNTEQALKMLVNHLPQIVIVDYRLQGMNGLQLVRQMQQVLQSLESNSPIEHQCRFF
ECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
LLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE
EEECCCCCCCHHHHCCCCHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFIQHKIMLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCHHHHHHHHHH
ALKSFFHASSKVTSEEFEIFAKDLLKIKSAVAFTLTPSLELAYISDQTMATELKQFELVK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHH
EPKGELKASLANYTLAVVAIDKPNMPYLVYAVSHQRILARIEQEQGVCITYQFEQSFEQS
CCHHHHHHHHCCEEEEEEEECCCCCCEEEEEECHHHHHHHHHHCCCEEEEEHHHHHHHHH
LLQNSFCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQKEIIELIVIILLIA
HHHCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEEECCHHHHHHHHHHHHHHH
ALGIVLSFLLYFKSKNQQVVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALS
HHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHC
QPQELDKIVDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHCCHHHHHHHH
SATSGKRLHIVVSESLPQFIELDGTKLFQLMTNIINNAFKYSTGSEVHCYMDLHLKANAK
HCCCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCC
NQRPVLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGLYTCNRLLEQIGGR
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCC
FRLRSQKGKGTTVLLHFPCQLSVVKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQ
EEEECCCCCCCEEEEECCCHHHHHHHHHHEEECCCEEEEEECCCCCHHHHHHHHHHHCCE
TFSTDNTEQALKMLVNHLPQIVIVDYRLQGMNGLQLVRQMQQVLQSLESNSPIEHQCRFF
ECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
LLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE
EEECCCCCCCHHHHCCCCHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA