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The map label for this gene is ppiD [H]

Identifier: 160874748

GI number: 160874748

Start: 1971740

End: 1973605

Strand: Direct

Name: ppiD [H]

Synonym: Sbal195_1631

Alternate gene names: 160874748

Gene position: 1971740-1973605 (Clockwise)

Preceding gene: 160874747

Following gene: 160874757

Centisome position: 36.87

GC content: 46.68

Gene sequence:

>1866_bases
ATGTTAGAAAAGATCCGCGATGGTTCGCAAGGCGTGATTGCTAAAGGCATTCTCGTACTTGTGATTTTATCTTTTGCATT
TGCAGGAGTCAGCAGTTACTTAGGTTCTACAACTGATGTGCCTGCAGCAGAAGTGAACGGTGACATAATCACTAAAGCCG
AGCTTGAGCAGGCTTACCAAAGCGAGCGCTCTCGTATGGAGCAACAGCTAGGTGAGATGTTTGCTGCGTTATCTGCTGAC
GAAAAATATCTACAAAGCATTAAGCAGAGCGTATTAGAGCGCTTAGTGGCTGACAAACTGATAGATCAAGCGGCTAAGGC
TATGGGGTTGCGTGTATCTGACGAACAGATCATTGCAGCCGTGAAAACTGAACCCGCATTCCAAACCGATGGCAAGTTTG
ATAACGATCGTTATCAGGCGATTCTACGTCAGTTAGGTTATCAACCACAGGCGTTCAGAGACATGATGCGCGTCGATATG
ACCCGTCGTCAGTTAACGGCTGCGCTAGTTGGTACTGAATTTGTGTTAGCTGGCGAAGCTAAGCAGTTAGCTGAGTTACA
AGGCCAAACTCGCGATGTGCGCTATTTAGTCGTTGATTCTGCGCCATTCTTAGCGACAGCGGTTGTGACTGACGAGCAAG
TGAAAAACTATTATGACGCAAACCAAGGGCAGTTTATGAGCCCTGAAATGGTGAGCTTAGAATATGTTGAGCTGAATGCG
GCTGATTTTGCTAAAAATAACCCAGTTTCTGACGAAGAAGCGCAAGCTTATTACGAAGAACATAAAGCGCAATACGTGTC
TAATGAGAAGCGTCTTGCCGCACATATTCTGGTTATGCCAGGTAGCGATGAAGCGGCTGCAAAAGCCAAGGCTGAAGATT
TAGCGAAGCAATTAGACAGCGGTGCCGATTTTGCTGATCTGGCTAAAGCTAACTCTGACGATACCTTGAGTGCAGAGCAG
GGCGGTAAACTGGATTGGTTTGAACCAGGTGTGATGGACCCCGCTTTCGATGCTGCATTATTTGCATTGAACAAAGGCCA
ACATTCAGCGGTAGTTAAAACTGACTTTGGTTTCCACATTATCAAGCTATTAGATGTGCAACCTGGTGTGACTGTACCCT
TTGCCGATGTAAAAGCTAAGATAGTGGCGCAATTGCAAGATAAGAAAGCGGTTGATCAATTCTATAGCTTACAAAGCAAA
TTGGCTGATACTAGCTATGAAGTGCCAGATACATTATCTGAAACCGCTAAAGCTGTGGGCGTCGATATTAAGACGACTCC
ACTGTTCTCTCGCGATAACGTTCCTGCTGCGCTGAACAAGCCAGACTTAGTTAAAGCTGCGTTCTCTGAAACTGTTATGC
TGAAAGGGTTAAACAGTGAAGTGATTGAGCTTGAACCTAACCACGTGGTGGTGGTTCGTGTGAAGGAACATCACGATGCG
GGCACTTTGGCCTTAGCGGAAGTGAAAGCCAATATCGCCGAACGTTTGAAGCAAGATCAAGCAAACGAAGCCGCCCGTGC
GAAAGCACAAGAGCTGATGGCACAAGTTAAAGCCGGTGCAATGGATCTTGGTTTAGTGGCTAAAGCAAAACTAGGCCGCG
GCGCGCAAGATGTTGATGCTGCTATTGTAGGCAAAGCGTTCCAAATGCCAACGCCAAGTACTTCTCCAGTTGTCGATACC
GTGGGTTTAGCAAATGGTTATGCCGTGGTTGCGCTAGATAAAGTCAACGCTGCTGAAGGTGTGAGTGATGAGCTGGTGAA
TGCGCTTAAACAACGCCTGAACGCACAATACAGCGAAGCAGACTACCGTGGCTTGATAGACTCACTTAAAGCCAATGCCA
AGGTGCTTTACCCTGTAGAAGAATGA

Upstream 100 bases:

>100_bases
ACCAGTGGTAGCGTCTGAATATTCCCCATAAATTACAGAAAGGCGCATCTCAAACTGATGCGCCTTTTTATTTTGTTAAT
CGCAACAAGCGAGAAATCTG

Downstream 100 bases:

>100_bases
GTTAAGCGAGGATAGCGCGTTGAACTGGTTATCCTACTTGTAAACTTCGATTAAAAAGGCCAAGTGATTTCACTTGGCCT
TTTTGTTTTTCAATGCGATG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQSERSRMEQQLGEMFAALSAD
EKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAAVKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDM
TRRQLTAALVGTEFVLAGEAKQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDSGADFADLAKANSDDTLSAEQ
GGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHIIKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSK
LADTSYEVPDTLSETAKAVGVDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGAMDLGLVAKAKLGRGAQDVDAAIVGKAFQMPTPSTSPVVDT
VGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEADYRGLIDSLKANAKVLYPVEE

Sequences:

>Translated_621_residues
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQSERSRMEQQLGEMFAALSAD
EKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAAVKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDM
TRRQLTAALVGTEFVLAGEAKQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDSGADFADLAKANSDDTLSAEQ
GGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHIIKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSK
LADTSYEVPDTLSETAKAVGVDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGAMDLGLVAKAKLGRGAQDVDAAIVGKAFQMPTPSTSPVVDT
VGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEADYRGLIDSLKANAKVLYPVEE
>Mature_621_residues
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQSERSRMEQQLGEMFAALSAD
EKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAAVKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDM
TRRQLTAALVGTEFVLAGEAKQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDSGADFADLAKANSDDTLSAEQ
GGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHIIKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSK
LADTSYEVPDTLSETAKAVGVDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGAMDLGLVAKAKLGRGAQDVDAAIVGKAFQMPTPSTSPVVDT
VGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEADYRGLIDSLKANAKVLYPVEE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=631, Percent_Identity=32.9635499207607, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1786238, Length=328, Percent_Identity=30.1829268292683, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67272; Mature: 67272

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEHHHHHHHHH
SERSRMEQQLGEMFAALSADEKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEE
VKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDMTRRQLTAALVGTEFVLAGEA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCH
KQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
HHHHHHCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECH
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHC
GADFADLAKANSDDTLSAEQGGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHI
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEE
IKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSKLADTSYEVPDTLSETAKAVG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
VDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
CCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEEECCCEEEEEEEECCCCC
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGAMDLGLVAKAKLGRGAQDVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
AIVGKAFQMPTPSTSPVVDTVGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEA
HHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCH
DYRGLIDSLKANAKVLYPVEE
HHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEHHHHHHHHH
SERSRMEQQLGEMFAALSADEKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEE
VKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDMTRRQLTAALVGTEFVLAGEA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCH
KQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
HHHHHHCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECH
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHC
GADFADLAKANSDDTLSAEQGGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHI
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEE
IKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSKLADTSYEVPDTLSETAKAVG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
VDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
CCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEEECCCEEEEEEEECCCCC
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGAMDLGLVAKAKLGRGAQDVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
AIVGKAFQMPTPSTSPVVDTVGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEA
HHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCH
DYRGLIDSLKANAKVLYPVEE
HHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]